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市場調查報告書
全球器官組織移植市場
Organ and Tissue Transplantation
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本報告已在2012年04月11日停止出版。
更改為出版
Organ and Tissue Transplantation
出版日期 : 2012年02月
商品編碼: 236773
本報告書為器官・組織移植的全球市場的相關分析，包含市場動向、產品概要、法規體制環境、業界之最近動態、相關企業、將來展望、各地區分析等，概述如下。
第1章 導論、調査方法、以及、產品定義
第2章 市場概要
- 概要
- 現狀以及將來分析
- 需求與供給的不均衡
- 器官不足對應政策
- 心臟停止患者 -潛在捐助者
- 移植費用
第3章 市場動向
- 生存捐助者的器官
- 持續受到注目的複合器官移植
- 增加的同意率 - 主要原因
- 移植旅行
- 達成重要任務的合作
- 提高移植必要性的高齡化與慢性疾病
- 仿生的胎生組織
第4章 移植對市場造成影響的主要課題
第5章 產品概要
- 組織與器官移植
- 器官移植
- 組織移植
- 移植免疫學
- 移植後的観察
- 捐助者類別
- 器官/組織捐贈的合格基準
- 對器官移植者的適合條件
- 檢査
- 免疫組織適合性 - 主要的障礙
- 移植安全性
- 等待順序清單
- 歷史
- 器官移植之主要里程碑
第6章 人工器官
第7章 保存溶液與免疫抑制劑
第8章 法規環境
第9章 產品開發與改良
第10章 近年的業界活動
第11章 近年企業活動
第12章 主要的市場企業
第13章 世界市場前景
第14章 美國市場
第15章 加拿大市場
第16章 歐洲市場
第17章 亞洲
第18章 拉丁美洲
第19章 其他地區市場
競爭檔案
Abstract
This report analyzes the worldwide markets for Organ and Tissue
Transplantation by Number of Procedures. The global and other markets (except
the US) are analyzed only by Organ Type - Heart, Kidneys, Liver, Pancreas, and
Lungs. The US market is analyzed both by Organ Type (Heart, Kidneys, Liver,
Pancreas, Lungs, & Intestine) and Tissue Type (Cornea, Heart Valve, Skin
Grafts, Vascular Grafts, Bone Marrow, and Bone Grafts). Also, the report
further analyzes the US market for Bone Graft Transplantation both by Graft
Type (Autologous Graft, Allograft, and Other Materials), and by Application
Type (General Orthopedics, Spinal Fusions, and Cranio/Maxillofacial). The
report provides separate comprehensive analytics for the US, Canada, Europe,
Asia, Latin America, and Rest of World. Annual estimates and forecasts are
provided for the period 2009 through 2015. Also, a six-year historic analysis
is provided for these markets. The report profiles 77 companies including many
key and niche players such as Abiomed Inc., Arbios Systems, Inc., Arrow
International, Inc., CryoLife, Inc., Exactech, Inc., Fresenius Medical Care AG
& Co. KGaA, Forticell Bioscience, Inc., Gambro AB, Genzyme Corporation, Jarvik
Heart, Inc., LifeCell Corporation, Medtronic, Inc., MicroMed Cardiovascular,
Inc., Organogenesis, Inc., SynCardia Systems, Terumo Corporation, Thoratec
Corporation, and WorldHeart Corporation. Market data and analytics are derived
from primary and secondary research. Company profiles are mostly extracted
from URL research and reported select online sources.
Table of Contents
1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS 1
- Study Reliability and Reporting Limitations 1
- Disclaimers 2
- Data Interpretation & Reporting Level 3
- Quantitative Techniques & Analytics 3
- Product Definitions and Scope of Study 3
- Tissue and Organ Transplantation 3
- Bone Graft Transplantation 4
- Product Definitions 4
- Organ Transplantation 4
- Heart Transplantation 4
- Kidney Transplantation 5
- Liver Transplantation 5
- Pancreas Transplantation 5
- Small Intestine Transplantation 5
- Lungs 5
- Tissue Transplantation 6
- Corneal Transplantation 6
- Blood Stem Cell Transplantation 6
- Bone Marrow Transplantation 6
- Heart Valves Transplantation 6
2. MARKET OVERVIEW 7
- A Quick Primer... 7
- Current and Future Analysis 7
- Demand and Supply Imbalance 8
- Measures to Address Organ Shortage 8
- Cardiac Arrest Death Patients: The Untapped Potential Donors 8
- Transplantation Expenses 9
3. MARKET TRENDS 10
- Living Donor Organs on the Rise 10
- Combined Organ Transplantation - Gaining Attention 10
- Increasing Consent Rates - A Key Factor 10
- Transplant Tourism - Creating Brighter Avenues 10
- Alliances to Play a Key Role 11
- Graying Population and Chronic Diseases Surge Need for Transplants 11
- Fetal Tissue for Bionic Devices - Assuming Importance 11
4. MAJOR ISSUES IMPACTING TRANSPLANTATION MARKET 12
- Organ Rejection - A Major Barrier to Transplantation 12
- Scarcity of Donor Organs - A Stumbling Block in Organ Transplantation 12
- Other Issues for Organ Transplantation 12
- Ethical Concerns in Transplants 12
- Bioethical Issues Hinder Organ Donation Process 13
- Lack of Requisite Expertise - Hindering Implantation Process 13
- Corneal Transplantation in 13
- Developing Countries: Key Challenges 13
5. PRODUCT OVERVIEW 14
- Organ and Tissue Transplantation 14
- Organ Transplantation 14
- Heart Transplantation 14
- Heart Diseases and Disorders 15
- Post Operative Complications and Consequences of Heart Transplants 15
- Bleeding 15
- Infection 15
- Arrythymia 15
- Heart Attack 16
- Coronary Artery Disease 16
- Respiratory Dysfunction 16
- Renal Dysfunction 16
- Graft Rejection and Dysfunction 16
- Death 16
- Kidney Transplantation 16
- Kidney Disorders and Diseases 17
- Donor Evaluation 17
- Waiting List 17
- Surgery/Post-Operation 17
- Post-Operative Supervision and Issues 17
- Liver Transplantation 18
- Liver Disorders and Diseases 19
- Pancreas Transplantation 19
- Post Operative Complications and Consequences of Pancreas Transplants 20
- Small Intestine Transplantation 20
- Intestine Disorders and Diseases 20
- Heart-and-Lung Transplantation 20
- Lung Transplantation 21
- Lung Diseases and Disorders 21
- Lung Patients Survival Statistics 21
- Tissue Transplantation 22
- Types of Grafts 22
- Autograft 22
- Allograft / Homograft 22
- Transplant Tolerance 23
- Isograft 23
- Xenograft 23
- Corneal Transplantation 23
- Penetrating Keratoplasty 24
- Lamellar (Non-Penetrating) Keratoplasty 24
- Aftercare 24
- Risks Associated with Corneal Transplants 25
- Transplantation Outcomes 25
- Morbidity and Mortality Rates 25
- Alternatives 25
- Blood Stem Cells 26
- Peripheral Blood Stem Cell Transplant 26
- Umbilical Cord Blood Stem Cell Transplant 26
- Bone Marrow and Hematopoietic Stem Cells 26
- Bone and Tissue Transplantation 26
- Bone Marrow Transplants 27
- Stem Cell Therapy 27
- Human Heart Valves 28
- Atrioventricular Valves 28
- Mitral Valve 28
- Tricuspid Valve 28
- Semilunar Valves 28
- Aortic Valve 28
- Pulmonic Valve 29
- Pathology of Valves 29
- Prosthetic Heart Valves 29
- Prosthetic Mechanical Valve 29
- Advantages 30
- Disadvantages 30
- Prosthetic Biologic Valve 30
- Advantages 31
- Disadvantages 31
- Fetal Cells 31
- Fetal Tissue for Transplantation 31
- Storage Duration Time 32
- Storage Time Period for Organs and Tissues 32
- Cold Ischemia Time 32
- Transplantation Immunology 32
- Acute Cellular Rejection 32
- Chronic Rejection 33
- Post Transplant Observations 33
- Types of Donors 33
- Alive Donors 33
- Related Donors 34
- Good Samaritans 34
- Rewarded/Forced Donors 34
- Deceased Donors 34
- Directed / Allocated 34
- Organs and Tissues Transplanted by Type of Donor 35
- Organ/Tissue Donation and Eligibility Criteria 35
- Factors Considered for Matching Recipients to Donor Organs 36
- Testing 36
- Blood Typing 36
- Tissue Typing 36
- Histocompatibility - A Major Barrier for Organ Transplantation 36
- Transplantation - Safety Requirements 37
- Waiting List 38
- Active Waiting List Patients 38
- Inactive Waiting List Patients 38
- History 38
- Major Milestones in Organ Transplantation 40
6. ARTIFICIAL ORGANS 41
- Artificial Organs Revolutionize Medical Technology Industry 41
- Artificial Organs 41
- Categorization of Artificial Organs 41
- External Artificial Organs 42
- Internal or Implantable Artificial Devices 42
- Artificial Heart 42
- Total Artificial Heart (TAH) 42
- Ventricle Assist Device (VAD) 42
- Right Ventricular Assist Systems (RVAS) 42
- Left Ventricular Assist Systems (LVAS) 42
- Various Ventricle Assist Devices Approved in the Recent Past 43
- Artificial Kidney (Dialyzer) 44
- Limitations of Artificial Kidney 44
- Artificial Liver 44
- Various Liver Assist Devices 44
- Categorization of Liver Devices 45
- Mechanical Systems 45
- Bio-Artificial Systems 45
- Artificial Pancreas 45
- Artificial Lungs (Oxygenator) 45
- Types of Artificial Lung 46
- Artificial Cornea 46
- Keratoprostheses 46
- Tissue Engineered Corneas 46
- Artificial Skin/Skin Replacement Products 46
- AlloDerm Regenerative Tissue Matrix 46
- Apligraf 46
- Cymetra Micronized AlloDerm Tissue 47
- Dermagraft 47
- Epicel 47
- Integra Products 47
- OrCel 47
- TransCyte 47
- Core Competitive Factors 48
- Market Outlook for Artificial Organs 48
7. PRESERVATION SOLUTIONS & IMMUNOSUPPRESSANT DRUGS 50
- Organ Preservation Solutions 50
- Celsior Solution 50
- Collins Solution 50
- Euro Collins Solution 50
- Custodiol(r) HTK Solution 50
- Hypothermosol 50
- ViaSpan 51
- Immunosuppressant Drugs 51
- Antibody Products for Treatment of Organ Transplant Rejection 51
- Antithymocyte Globulin 51
- ATGAM 51
- Campath/MabCampath 52
- Thymoglobulin 52
- Therapeutic Antibody Products 52
- Antiproliferative Agents 52
- Azathioprine 52
- CellCept 52
- Certican 52
- Myfortic 53
- Calcineurin Inhibitors 53
- Cyclosporine 53
- Gengraf 53
- Neoral 53
- Pulminiq 53
- Tacrolimus 53
- Prograf 54
- TOR Inhibitors 54
- Side Effects of Immunosuppression Therapy 54
- Select Immunosuppressant Drug Players 54
- Astellas Pharma US, Inc. (USA) 54
- F.Hoffmann-La Roche Ltd. (Switzerland) 54
- Novartis AG (Switzerland) 55
- Wyeth (USA) 55
8. REGULATORY ENVIRONMENT 56
- Transplant Center 56
- Organ Procurement Organization (OPO) 56
- Health Resources and Services Administration (HRSA) 56
- Division of Transplantation (DoT) 56
- United Network for Organ Sharing (UNOS) 56
- Organ Procurement and Transplantation Network (OPTN) 56
- University Renal Research and Education Association (URREA) 57
- Scientific Registry of Transplant Recipients (SRTR) 57
- Funding Sources 57
- Patient Education and Advocacy Organizations 57
- Legal Framework for Transplantation 58
- Legislation Covering Organ Transplant 58
- Organ Transplantation and Ethics 59
- Regulations Governing Artificial Organs 60
9. PRODUCT DEVELOPMENT/INNOVATIONS 61
- Dr. Reddy' s to Launch Tacrolimus Capsules in US 61
- ApaTech(r) Unveils Actifuse(r) MIS Bone Graft Delivery System 61
- DePuy Spine Introduces HEALOS(r) Fx Injectable Bone Graft Replacement 61
- Watson Laboratories Receives FDA Approval for Tacrolimus 5 mg 62
- RTI Biologics Introduces Osteochondral Allograft in San Francisco 62
- Pluristem Develops New Cell Graft for Cancer Patients 62
- CryoLife Develops Cryopreserved Orthopaedic Tissues Implants 63
- Japanese Innovators Develop New Prognostic Scoring Model for Liver
Transplants 63
- EUREKA project E! 2674 MIDAS Develops New Test to Improve Graft Survival 63
10. RECENT INDUSTRY ACTIVITY 64
- International Stem Cell Inks Partnership Deal with Sankara Nethralaya 64
- BGS Global Hospitals Inaugurates New Multi-Organ Transplants Center in
India 64
- Vietnamese Ministry of Health to Establish Organ Transplant Coordination
Center 64
- Novartis Secures US FDA Approval for Zortress Oral Tablets 64
- Humacyte Enters into Strategic Alliance with Xcellerex 65
- Osteotech Signs Agreement with Community Tissue Services 65
- Tissue Banks International Enters into a Partnership with Northwest Tissue
Services 65
- Roche Secures FDA Approval for Valcyte 66
- Astellas Pharma Secures FDA Clearance for Prograf and MMF Drug Combination
66
- Astellas Pharma Receives Additional Approval for Prograf 66
- Novadaq(r) Obtains US FDA Approval for SPY(r) System 66
- St. Jude Medical' s Heart Valve Obtains US FDA Approval 67
- Zimmer and Tutogen Expand Distribution Partnership 67
11. CORPORATE ACTIVITY IN THE RECENT PAST- A PERSPECTIVE BUILDER 68
- Leman Cardiovascular Acquires Hancock Jaffe Laboratories 68
- Nabi Acquires Commercialization Rights of ATG-Fresenius S for North
America 68
- Cytopia and Novartis Ink Research Collaboration and Global License
Agreement 68
- ZLB Behring Inks Agreement with MedImmune 69
- Japanese Team To Perform Liver Transplants in Hyderabad 69
- Nabi Bags Approval for HB Intravenous in Liver Transplant Patients 69
- Schering-Plough Announces PROTECT study Initiation 69
- Allegheny General Hospital To Establish Adult Liver Transplantation Center
in Oakland 69
- Global Hospitals to Setup an Organ Transplant Center in Kolkata 70
- GCC to Establish Organ Transplant Center 70
- Delhi-Based Hospital Offers Help in Setting Up of Liver Transplant Center
in Lahore 70
- Kaiser To Shut Down Kidney Transplant Center 70
- Abiomed Obtains FDA Approval for Selling Artificial Hearts 70
- Astellas Bags FDA Approval to Use Prograf in Heart Transplant Patients 70
- New York State Department of Health Approves Program for Kidney Transplant
for Queen' s Community 71
- National Heart Institute Conducts First Double Lung Transplant in Malaysia
71
- The Netherlands Obtains Orphan Drug Designations for Treatment of DGF 71
- Papworth Transplants First Beating Human Heart in the UK 71
- Enzon to Return ATG-Fresenius S Rights to Fresenius Biotech 72
- Schering-Plough to Conduct ' PROTECT' Study 72
- Community Tissue Services Selects NOVA 2200 Supercritical Carbon Dioxide
Sterilization Technology 72
- CryoLife Inks Agreement with The Magdi Yacoub Institute to Enhance
Xenografts in Human Transplantation 73
- ReGen Inks Exclusive Marketing Deals with Polymedic and Xmedica 73
- University of California-Irvine Announces Closure of Liver-Transplantation
Program 73
- Swedish Health Services Bags Approval for Liver Transplant Program 74
- New Organ Transplant Research Center in South Korea 74
- Child Lung Transplant Unit to be opened in Melbourne Hospital 74
- Narayana Hrudayalaya Health City Establishes Exclusive Organ Transplant
Hospital 74
- Liver Transplant Facility in Delhi Region 74
- First Liver Transplant Research Institute in China 74
- PIMS to establish Liver Transplant Unit 75
- Liver Transplant Programme in Pakistan 75
- Isotechnika Gains FDA Approval 75
- FDA Offers Approval for Brain Stem Cell Transplant Trial 75
- Methodist Specialty and Transplant Hospital Gains Approval to Execute
Liver Transplants 75
- Cubist Pharma Enters into Licensing Agreement with XTL Biopharmaceuticals
75
- Jackson Memorial Receives Approval from the U.S. Centers for Medicare and
Medicaid Services 76
- Royal Perth Hospital to Open Lung Transplant Unit in Perth 76
- Mater Hospital Opens Lung Transplant Unit in Dublin 76
- Genzyme Makes a Synergistic Purchase of Ilex Oncology 77
- NIAID Sets Up Clinical Consortium to Enhance Organ Transplants Success 77
- Chiron files NDA for Pulminiq Inhalation Solution 77
- Roche Acquires IL-15 Antagonist 77
- Genzyme Completes Acquisition of SangStat 78
12. FOCUS O SELECT GLOBAL PLAYERS 79
- Abiomed, Inc. (USA) 79
- Arbios Systems, Inc. (USA) 79
- Arrow International, Inc. (USA) 80
- CryoLife, Inc.(USA) 80
- Exactech, Inc. (USA) 80
- Fresenius Medical Care AG & Co. KGaA (Germany) 81
- Forticell Bioscience, Inc. (USA) 81
- Gambro AB (Sweden) 81
- Genzyme Corporation (USA) 82
- Jarvik Heart, Inc. (USA) 82
- LifeCell Corporation (USA) 83
- Medtronic, Inc. (USA) 83
- MicroMed Cardiovascular, Inc. (USA) 84
- Organogenesis, Inc. (USA) 84
- SynCardia Systems (USA) 84
- Terumo Corporation (Japan) 85
- Thoratec Corporation (USA) 85
- WorldHeart Corporation (USA) 85
13. GLOBAL MARKET PERSPECTIVE 87
- Table 1: World Recent Past, Current & Future MarketAnalysis for Organ
Transplantation by Geographic Region -US, Canada, Europe, Asia (including
Japan), Latin Americaand Rest of World Independently Analyzed by Numberof
Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart) 87
- Table 2: World Historic Review for Organ Transplantation by Geographic
Region - US, Canada, Europe, Asia (including Japan), Latin America and Rest of
World IndependentlyAnalyzed by Number of Procedures for Years 2003 through2008
(includes corresponding Graph/Chart) 88
- Table 3: World 11-Year Perspective for Organ Transplantationby Geographic
Region - Percentage Breakdown of Number of Procedures for US, Canada, Europe,
Asia (including Japan), Latin America and Rest of World Markets for Years
2003,2007 & 2012 (includes corresponding Graph/Chart) 89
- Table 4: World Recent Past, Current & Future Market Analysis for Heart
Transplantation by Geographic Region - US,Canada, Europe, Asia (including
Japan), Latin Americaand Rest of World Independently Analyzed by Numberof
Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart) 90
- Table 5: World Historic Review for Heart Transplantation by Geographic
Region - US, Canada, Europe, Asia (including Japan), Latin America and Rest of
World IndependentlyAnalyzed by Number of Procedures for Years 2003 through2008
(includes corresponding Graph/Chart) 91
- Table 6: World 11-Year Perspective for Heart Transplantationby Geographic
Region - Percentage Breakdown of Number of Procedures for US, Canada, Europe,
Asia (including Japan), Latin America and Rest of World Markets for Years
2003,2007 & 2012 (includes corresponding Graph/Chart) 92
- Table 7: World Recent Past, Current & Future MarketAnalysis for Kidney
Transplantation by Geographic Region -US, Canada, Europe, Asia (including
Japan), Latin Americaand Rest of World Independently Analyzed by Numberof
Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart) 93
- Table 8: World Historic Review for Kidney Transplantationby Geographic
Region - US, Canada, Europe, Asia (including Japan), Latin America and Rest of
World IndependentlyAnalyzed by Number of Procedures for Years 2003through 2008
(includes corresponding Graph/Chart) 94
- Table 9: World 11-Year Perspective for Kidney Transplantationby Geographic
Region - Percentage Breakdown of Numberof Procedures for US, Canada, Europe,
Asia (includingJapan), Latin America and Rest of World Marketsfor Years 2005,
2010 & 2015 (includes corresponding Graph/Chart) 95
- Table 10: World Recent Past, Current & Future MarketAnalysis for Liver
Transplantation by Geographic Region -US, Canada, Europe, Asia (including
Japan), Latin Americaand Rest of World Independently Analyzed by Numberof
Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart) 96
- Table 11: World Historic Review for Liver Transplantationby Geographic
Region - US, Canada, Europe, Asia(including Japan), Latin America and Rest of
WorldIndependently Analyzed by Number of Procedures for Years2003 through 2008
(includes corresponding Graph/Chart) 97
- Table 12: World 11-Year Perspective for LiverTransplantation by Geographic
Region - PercentageBreakdown of Number of Procedures for US, Canada,Europe,
Asia (including Japan), Latin America andRest of World Markets for Years 2003,
2007 &2012 (includes corresponding Graph/Chart) 98
- Table 13: World Recent Past, Current & Future MarketAnalysis for
Pancreas Transplantation by GeographicRegion - US, Canada, Europe, Asia
(including Japan),Latin America and Rest of World Independently Analyzedby
Number of Procedures for Years 2009 through 2015(includes corresponding
Graph/Chart) 99
- Table 14: World Historic Review for PancreasTransplantation by Geographic
Region - US, Canada,Europe, Asia (including Japan), Latin America andRest of
World Independently Analyzed by Number ofProcedures for Years 2003 through
2008 (includescorresponding Graph/Chart) 100
- Table 15: World 11-Year Perspective for Pancreas Transplantation by
Geographic Region - PercentageBreakdown of Number of Procedures for US,
Canada,Europe, Asia (including Japan), Latin America andRest of World Markets
for Years 2005, 2010 & 2015(includes corresponding Graph/Chart) 101
- Table 16: World Recent Past, Current & Future MarketAnalysis for Lung
Transplantation by Geographic Region -US, Canada, Europe, Asia (including
Japan), Latin Americaand Rest of World Independently Analyzed by Number of
Procedures for Years 2009 through 2015 (includescorresponding Graph/Chart) 102
- Table 17: World Historic Review for Lung Transplantationby Geographic
Region - US, Canada, Europe, Asia (including Japan), Latin America and Rest of
World IndependentlyAnalyzed by Number of Procedures for Years 2003 through2008
(includes corresponding Graph/Chart) 103
- Table 18: World 11-Year Perspective for LungTransplantation by Geographic
Region - PercentageBreakdown of Number of Procedures for US, Canada,Europe,
Asia (including Japan), Latin America andRest of World Markets for Years 2003,
2007 &2012 (includes corresponding Graph/Chart) 104
- Table 19: World Recent Past, Current & Future MarketAnalysis for
Corneal Transplantation by Geographic Region - US, Canada, Europe, Asia
(including Japan), Latin Americaand Rest of World Independently Analyzed by
Number of Procedures for Years 2009 through 2015 (includescorresponding
Graph/Chart) 105
- Table 20: World Historic Review for Corneal Transplantationby Geographic
Region - US, Canada, Europe, Asia (including Japan), Latin America and Rest of
World IndependentlyAnalyzed by Number of Procedures for Years 2003through 2008
(includes corresponding Graph/Chart) 106
- Table 21: World 11-Year Perspective for CornealTransplantation by
Geographic Region - PercentageBreakdown of Number of Procedures for US,
Canada,Europe, Asia (including Japan), Latin America andRest of World Markets
for Years 2005, 2010 & 2015(includes corresponding Graph/Chart) 107
14. THE UNITED STATES 108
- A. Market Analysis 108
- Current and Future Analysis 108
- Analysis by Value Sales 108
- Liver Transplantation Sustains Dominance in Value Sales 108
- Skin Grafts Takes the Largest Chunk in Tissue Transplantations 108
- Analysis by Number of Procedures 108
- Kidney Transplants Represent the Largest, While Intestine Transplants
to Register Fastest Growth 108
- Skin Grafts - Largest and Fastest Growing Tissue Segment 109
- Bone Graft Procedure Volume by Graft Type and Application 109
- A Few Organ Transplant Facts and Figures in the US 109
- Sources of Donor Organs 109
- Table 22: US Kidney Donations by Donor Type - Cadaveric and Living for
Years 2003 through 2008 (includes corresponding Graph/Chart) 110
- Table 23: US Liver Donations by Donor Type -Cadaveric and Living for
Years 2003 through 2008 (includes corresponding Graph/Chart) 110
- Table 24: US Heart Donations by Cadaveric DonorType for Years 2003
through 2008 (includescorresponding Graph/Chart) 111
- Table 25: US Lung Donations by Donor Type -Cadaveric and Living for
Years 2003 through 2008 (includes corresponding Graph/Chart) 111
- Table 26: US Pancreas Donations by Donor Type - Cadaveric and Living
for Years 2003 through 2008 (includes corresponding Graph/Chart) 112
- Table 27: US Intestine Donations by Donor Type - Cadaveric and Living
for Years 2003 through 2008 (includes corresponding Graph/Chart) 112
- Key Market Trends 112
- Innovative Means of Organ Procurement to Increase Organ Donations 112
- A New Technique to Enhance and Extend Kidney Transplants 113
- California Stands Up Against Insurance on HIV Patients'
Transplantation 113
- Awareness Programs to Address Shortage of Minority Donors 113
- Organs and Tissues on A Recovery Spree 113
- Unexamined Human Tissue Transplants - A Major Threat 114
- Defective Medical Implants - A Health Hazard 114
- Eye Infections from Usage of MoistureLoc Leads to Corneal Transplants
114
- Incidence of Organ Transplants 115
- Table 28: Incidence of Organ Transplant per 1 MillionPopulation in the
US by Type - Kidney, Liver,Heart, Lung, Pancreas, Intestine, and Heart-Lung
Transplants, for the Year 2003 through 2008(includes corresponding
Graph/Chart) 115
- Table 29: Incidence of Organ Transplants (Kidney,Liver, Heart, Lung,
Pancreas, Intestine, and Heart-Lung) per 1 Million Population in the US by
RecipientRace (White, African American, Asian, Hispanic, andOther) for 2008
(includes correspondingGraph/Chart) 115
- Table 30: Incidence of Organ Transplants (Kidney,Liver, Heart, Lung,
Pancreas, Intestine, andHeart-Lung) per 1 Million Population in the USby
Recipient Gender (Male, and Female) for2008 (includes corresponding
Graph/Chart) 116
- Table 31: Incidence of Organ Transplants (Kidney,Liver, Heart, Lung,
Pancreas, Intestine, and Heart-Lung) per 1 Million Population in the US by
Recipient Age(65+ Years, 50-64 Years, 35-49 Years, 18-34 Years,11-17 Years,
6-10 Years, 1-5 Years, <1 Year) for2008 (includes corresponding
Graph/Chart) 116
- Heart Transplantation 117
- Table 32: Heart Transplant Life Expectancyin the US (2009): As of 2009
(includescorresponding Graph/Chart) 117
- Lung Transplantation 117
- Heart-Lung Transplantation 118
- Waiting List 118
- Table 33: Waiting List of Patients As of July 2010(includes
corresponding Graph/Chart) 118
- Table 34: Waiting List of Active and InactivePatients for the Year
2008 (includescorresponding Graph/Chart) 119
- Waiting List for Heart Transplants 119
- Table 35: Waiting List of Active Patients for Heartfor Years 2000 to
2008 (includes corresponding Graph/Chart) 120
- Categorized by Diseases 120
- Categorized by Age 120
- Categorized by Race 120
- Death Rates on the Waiting Lists 120
- Kidney Transplantation Waiting List 121
- Categorized by Age 121
- Categorized by Race 121
- Waiting List for Liver Transplants 121
- Categorized by Age 121
- Categorized by Race 122
- Categorized by Gender 122
- Categorized by Diseases 122
- Categorized by Re-Transplant Necessity 122
- Pancreas Transplant Waiting List 122
- Simultaneous Pancreas Kidney Transplantation Waiting List 122
- Waiting List for Lung Transplants 122
- Categorized by Age 123
- Categorized by Primary Diagnoses 123
- Categorized by Gender and Ethnic Makeup 123
- Waiting List for Intestine Transplants 123
- Death Rates on Waiting List 123
- Patient Survival Rate 124
- Table 36: Unadjusted Patient Survival Rate (*) byOrgan Type for 1-Year
and 5-Years (includes corresponding Graph/Chart) 124
- Multi-Organ Transplant Gaining Momentum 125
- Table 37: Multi-Organ Transplants in the US:2005-2008 (includes
correspondingGraph/Chart) 125
- Immunosuppression Therapy 125
- Immunosuppression Therapy for Heart Transplant Recipients 125
- Table 38: Usage Rates of Major Immunosuppressantsat Discharge by Organ
Type for the Year 2008(includes corresponding Graph/Chart) 126
- Immunosuppression Therapy for Kidney Transplant Recipients 126
- Immunosuppression Therapy for Pancreas Transplants 126
- Immunosuppression Therapy for Lung Transplant Recipients 126
- Table 39: Usage Rates of Induction Drugs ForLung Transplant Recipients
in 2008 (includes corresponding Graph/Chart) 127
- Immunosuppression Therapy, Following Bone Marrow Transplantation 127
- Table 40: US Recent Past, Current & FutureMarket Analysis for
Immunosuppressive DrugTherapy Following Bone Marrow Transplantationby
Category - For GVHD and Maintenance Independently Analyzed with Annual Sales
Figuresin US$ Million for Years 2009 through 2015(includes corresponding
Graph/Chart) 127
- Table 41: US Historic Review for ImmunosuppressiveDrug Therapy
Following Bone Marrow Transplantationby Category - For GVHD and Maintenance
Independently Analyzed with Annual Sales Figuresin US$ Million for Years
2003 through 2008(includes corresponding Graph/Chart) 128
- Table 42: US 11-Year Perspective for Immunosuppressive Drug Therapy
Following Bone Marrow Transplantation by Category - Percentage Breakdown of
Dollar Sales For GVHD and Maintenance Independently Analyzed with Annual
Sales Figuresin US$ Million for Years 2005, 2010, and 2015 128
- Immunosuppression Therapy, Following Blood Stem Cell Transplantation
129
- Table 43: US Recent Past, Current & Future Market Analysis for
Immunosuppressive Drug Therapy Following Blood Stem Cell Transplantation by
Category - For GVHD and Maintenance Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2015 (includes corresponding
Graph/Chart) 129
- Table 44: US Historic Review for ImmunosuppressiveDrug Therapy
Following Blood Stem Cell Transplantationby Category - For GVHD and
Maintenance Independently Analyzed with Annual Sales Figuresin US$ Million
for Years 2003 through 2008(includes corresponding Graph/Chart) 130
- Table 45: US 11-Year Perspective for Immunosuppressive Drug Therapy
Following BloodStem Cell Transplantation by Category - Percentage Breakdown
of Dollar Sales For GVHD and Maintenance Independently Analyzed with Annual
Sales Figuresin US$ Million for Years 2005, 2010, and 2015 130
- The United Network for Organ Sharing 130
- The American Association of Tissue Banks (AATB) 131
- Accredited Banks from Select US States 131
- Eye Banks from Select US States 133
- Number of Transplant Center Programs 134
- Table 46: Number of Transplant Center Programsfor the Years 1990, 1997
and 2000 (includescorresponding Graph/Chart) 134
- Table 47: Average Number of Transplants PerProgram for the Years 1990,
1997 and 2000(includes corresponding Graph/Chart) 135
- B. Market Analytics 136
- Table 48: US Recent Past, Current & Future MarketAnalysis for Organ
Transplantation by Organ Type -Heart, Kidney, Liver, Pancreas, Lung and
Intestine Independently Analyzed with Annual Sales Figuresin US$ Million for
Years 2009 through 2015(includes corresponding Graph/Chart) 136
- Table 49: US Historic Review for Organ Transplantationby Organ Type -
Heart, Kidney, Liver, Pancreas, Lungand Intestine Independently Analyzed
with AnnualSales Figures in US$ Million Years 2003 through2008 (includes
corresponding Graph/Chart) 137
- Table 50: US 11-Year Perspective for OrganTransplantation by Organ Type
- PercentageBreakdown of Dollar Sales for Heart, Kidney,Liver, Pancreas,
Lung and Intestine Markets forYears 2005, 2010 & 2015
(includescorresponding Graph/Chart) 138
- Table 51: US Recent Past, Current & Future MarketAnalysis for
Tissue Transplantation by Tissue Type -Cornea, Heart Valves and Skin Grafts
Independently Analyzed with Annual Sales Figures in US$ Millionfor Years
2009 through 2015 (includescorresponding Graph/Chart) 139
- Table 52: US Historic Review for Tissue Transplantationby Tissue Type -
Cornea, Heart Valves and Skin Grafts Independently Analyzed with Annual
Sales Figuresin US$ Million for Years 2003 through 2008(includes
corresponding Graph/Chart) 140
- Table 53: US 11-Year Perspective for TissueTransplantation by Tissue
Type - Percentage Breakdownof Dollar Sales for Cornea, Heart Valves and
SkinGrafts Markets for Years 2005, 2010 & 2015(includes corresponding
Graph/Chart) 140
- By Number of Procedures 141
- Table 54: US Recent Past, Current & Future MarketAnalysis for Organ
Transplantation by Organ Type -Heart, Kidney, Liver, Pancreas, Lung and
Intestine Independently Analyzed by Number of Proceduresfor Years 2009
through 2015 (includescorresponding Graph/Chart) 141
- Table 55: US Historic Review for Organ Transplantationby Organ Type -
Heart, Kidney, Liver, Pancreas, Lungand Intestine Independently Analyzed by
Number of Procedures for Years 2003 through 2008 (includes corresponding
Graph/Chart) 142
- Table 56: US 11-Year Perspective for OrganTransplantation by Organ Type
- PercentageBreakdown of Number of Procedures for Heart,Kidney, Liver,
Pancreas, Lung and Intestine Marketsfor Years 2005, 2010 & 2015
(includescorresponding Graph/Chart) 143
- Table 57: US Recent Past, Current & Future MarketAnalysis for
Tissue Transplantation by Tissue Type -Cornea, Heart Valves, Skin Grafts,
Vascular Grafts,Bone Marrow and Bone Grafts IndependentlyAnalyzed by Number
of Procedures forYears 2009 through 2015 (includescorresponding Graph/Chart)
144
- Table 58: US Historic Review for Tissue Transplantationby Tissue Type -
Cornea, Heart Valves, Skin Grafts,Vascular Grafts, Bone Marrow and Bone
Grafts Independently Analyzed by Number of Proceduresfor Years 2003 through
2008 (includescorresponding Graph/Chart) 145
- Table 59: US 11-Year Perspective for TissueTransplantation by Tissue
Type - Percentage Breakdownof Number of Procedures for Cornea, Heart
Valves,Skin Grafts, Vascular Grafts, Bone Marrow andBone Grafts Markets for
Years 2005, 2010 & 2015(includes corresponding Graph/Chart) 146
- Table 60: US Recent Past, Current & Future MarketAnalysis for Bone
Graft Transplantation by Graft Type - Autologous Graft, Allograft and Other
Materials Independently Analyzed by Number of Proceduresfor Years 2009
through 2015 (includescorresponding Graph/Chart) 147
- Table 61: US Historic Review for Bone GraftTransplantation by Graft
Type - Autologous Graft,Allograft and Other Materials Independently
Analyzedby Number of Procedures for Years 2003 through2008 (includes
corresponding Graph/Chart) 148
- Table 62: US 11-Year Perspective for Bone Graft Transplantation by
Graft Type - PercentageBreakdown of Number of Procedures forAutologous
Graft, Allograft and Other MaterialsMarkets for Years 2005, 2010 & 2015
(includes corresponding Graph/Chart) (includescorresponding Graph/Chart) 148
- Table 63: US Recent Past, Current & Future MarketAnalysis for Bone
Graft Transplantation byApplication - General Orthopedics, Spinal Fusionsand
Cranio/Maxillofacial Independently Analyzed byNumber of Procedures for Years
2009 through 2015(includes corresponding Graph/Chart) 149
- Table 64: Historic Review for Bone GraftTransplantation by Application
- General Orthopedics,Spinal Fusions and Cranio/Maxillofacial
IndependentlyAnalyzed by Number of Procedures for Years 2003through 2008
(includes corresponding Graph/Chart) 150
- Table 65: US 11-Year Perspective for Bone Graft Transplantation by
Application - PercentageBreakdown of Number of Procedures forGeneral
Orthopedics, Spinal Fusions and Cranio/Maxillofacial Markets forYears 2005,
2010 & 2015 (includescorresponding Graph/Chart) 150
15. CANADA 151
- A. Market Analysis 151
- Current and Future Analysis 151
- Canadians More Receptive to Organ Transplants 151
- Waiting List 151
- Table 66: Canadian Patients (Active and Inactive)on Waiting List by
Organ Type for 2009 and 1H 2010 (*)(includes corresponding Graph/Chart) 152
- Organ Donation 152
- Table 67: Canadian Organ Donations by DonorType - Cadaveric and Living
for Years 2003through 2007 (includes correspondingGraph/Chart) 152
- Success Rate of Organ Transplants 153
- Table 68: Success Rate of Organ TransplantsAfter 1-Year (includes
correspondingGraph/Chart) 153
- B. Market Analytics 154
- Table 69: Canadian Recent Past, Current & FutureMarket Analysis for
Organ Transplantation byOrgan Type - Heart, Kidney, Liver, Pancreas andLung
Independently Analyzed by Number ofProcedures for Years 2009 through
2015(includes corresponding Graph/Chart) 154
- Table 70: Canadian Historic Review for Organ Transplantation by Organ
Type - Heart, Kidney,Liver, Pancreas and Lung Independently Analyzed
byNumber of Procedures for Years 2003 through 2008(includes corresponding
Graph/Chart) 155
- Table 71: Canadian 11-Year Perspective for Organ Transplantation by
Organ Type - PercentageBreakdown of Number of Procedures for Heart,Kidney,
Liver, Pancreas and Lung Markets forYears 2005, 2010 & 2015
(includescorresponding Graph/Chart) 156
16. EUROPE 157
- A. Market Analysis 157
- Current and Future Analysis 157
- Table 72: Number of Organ Transplants in Select European Countries by
Organ: 2009 (includes corresponding Graph/Chart) 157
- Table 73: Number of Deceased Organ Donorsin Select European Countries
for 2008 & 2009(includes corresponding Graph/Chart) 158
- Focus on Select Regions 158
- The United Kingdom 158
- UK Organ Transplantation System: An Overview 158
- Organ Transplantation in the UK 158
- Table 74: UK Organ Transplantationsfor the Years 2007 and 2008
(includescorresponding Graph/Chart) 159
- Table 75: Waiting List (Active and Inactive) byOrgan in the UK for the
Years 2007 and 2008 (includes corresponding Graph/Chart) 159
- Corneal Transplantation in the UK 160
- Bladder Transplantation: A Roaring Success 160
- Spain 160
- Organ Transplantation in Spain 160
- France 161
- Table 76: Organ Transplantations in Francefor the Years 2006 through
2008 (includescorresponding Graph/Chart) 161
- Table 77: Waiting List (Active and Inactive) byOrgan in France for the
Years 2006 through2008 (includes corresponding Graph/Chart) 162
- Italy 162
- Surge in Organ Transplants 162
- Russia 162
- Organ Transplantations Show a Downward Trend in Russia 162
- Turkey 162
- Akdeniz University - A World-Renowned Transplantation Center 162
- B. Market Analytics 163
- Table 78: European Recent Past, Current & FutureMarket Analysis for
Organ Transplantation byOrgan Type - Heart, Kidney, Liver, Pancreas andLung
Independently Analyzed by Number ofProcedures for Years 2009 through
2015(includes corresponding Graph/Chart) 163
- Table 79: European Historic Review for Organ Transplantation by Organ
Type - Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by
Numberof Procedures for Years 2003 through 2008 (includes corresponding
Graph/Chart) 164
- Table 80: European 11-Year Perspective for Organ Transplantation by
Organ Type - PercentageBreakdown of Number of Procedures for Heart,Kidney,
Liver, Pancreas and Lung Markets forYears 2005, 2010 & 2015
(includescorresponding Graph/Chart) 165
17. ASIA 166
- A. Market Analysis 166
- Current & Future Analysis 166
- Focus on Select Regions 166
- Australia 166
- Key Facts on Organ and Tissue Transplantation in Australia 166
- Australia Registers Highest Success Rate in Transplantation 167
- Table 81: Organ Transplantation in Australia by Organ Type: 2008
(includes corresponding Graph/Chart) 167
- Table 82: Organ Transplant Waiting List byOrgan Type: As of January
2010 (includes corresponding Graph/Chart) 167
- Kidney Transplantation Snapshots 167
- Organ Donor Register 168
- China 168
- Organ Transplantations in China: Year 2005 & 2006 in Review 168
- Transplantation Tourism in China 168
- Low Transplant Success Rate Due to Unskilled Professionals 168
- Cost Effective Transplant Procedures Lure Foreign Patients 169
- Illegal Activities for Harvesting Organs in China 169
- Regulations on Organ Transplantation 169
- Regulations on Brain Death 170
- India 170
- Overview of Renal Transplantation 170
- Transplantation Expenses in India 171
- Indian Government to Amend Organ Transplantation Rules 171
- Singapore 171
- Awareness Programs to Increase Living Kidney Donations in Singapore 171
- Taiwan 172
- Taiwan Competes with the US in Kidney and Liver Transplant Survival
Rates 172
- B. Market Analytics 173
- Table 83: Asia Recent Past, Current & Future Market Analysis for
Organ Transplantation by Organ Type -Heart, Kidney, Liver, Pancreas and Lung
Independently Analyzed by Number of Procedures for Years 2009through 2015
(includes corresponding Graph/Chart) 173
- Table 84: Asia Historic Review for Organ Transplantationby Organ Type
- Heart, Kidney, Liver, Pancreas andLung Independently Analyzed by Number of
Proceduresfor Years 2003 through 2008 (includes corresponding Graph/Chart)
174
- Table 85: Asia 11-Year Perspective for OrganTransplantation by Organ
Type - Percentage Breakdownof Number of Procedures for Heart, Kidney,
Liver,Pancreas and Lung Markets for Years 2003, 2007 &2012 (includes
corresponding Graph/Chart) 175
18. LATIN AMERICA 176
- A. Market Analysis 176
- Current & Future Analysis 176
- Brazil - A Major Transplant Market 176
- B. Market Analytics 177
- Table 86: Latin American Recent Past, Current & Future Market
Analysis for Organ Transplantation by Organ Type - Heart, Kidney, Liver,
Pancreas and Lung Independently Analyzed by Number of Procedures for Years
2009through 2015 (includes corresponding Graph/Chart) 177
- Table 87: Latin American Historic Review for Organ Transplantation by
Organ Type - Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed
by Numberof Procedures for Years 2003 through 2008(includes corresponding
Graph/Chart) 178
- Table 88: Latin American 11-Year Perspective for Organ Transplantation
by Organ Type - Percentage Breakdownof Number of Procedures for Heart,
Kidney, Liver,Pancreas and Lung Markets for Years 2003, 2007 &2012
(includes corresponding Graph/Chart) 179
19. REST OF WORLD 180
- A. Market Analysis 180
- Current & Future Analysis 180
- Kuwait - A Rapidly Emerging ' Third World' Country in Organ Transplants
180
- South Africa 180
- Key Statistical Findings on Organ and Cornea Transplants 180
- Table 89: Number of Organ and Cornea Transplantsin South Africa for
Years 2005 through 2009(includes corresponding Graph/Chart) 180
- Table 90: Number of Organ Transplants (Excluding Cornea) in South
Africa by Organ for Years 2008 &2009 (includes corresponding
Graph/Chart) 181
- Table 91: Number of Organ Transplants in Adult Patients in South
Africa by Organ for yeas 2008 &2009 (includes corresponding Graph/Chart)
181
- Table 92: Number of Organ Transplants in Adolescent Patients in South
Africa by Organ for Years 2008 &2009 (includes corresponding
Graph/Chart) 182
- Table 93: Number of Organ Transplants (Excluding Cornea) in Pediatric
Patients in South Africa byOrgan for Years 2008 & 2009
(includescorresponding Graph/Chart) 182
- Table 94: Number of Heart Transplants in SouthAfrica for Years 2005
through 2009 (includes corresponding Graph/Chart) 183
- Table 95: Number of Kidney Transplants inSouth Africa for Years 2005
through 2009(includes corresponding Graph/Chart) 183
- Table 96: Number of Lung Transplants in SouthAfrica for Years 2005
through 2009 (includes corresponding Graph/Chart) 183
- Table 97: Organ Transplants (Excluding Cornea)in South Africa by
Region (2008 & 2009): Percentage Breakdown of Volume Procedures for Cape
Town, Johannesburg, Durban, Pretoria and Bloemfontein (includes
corresponding Graph/Chart) 184
- Table 98: Cornea Transplants in South Africa byRegion (2008 &
2009): Percentage Breakdown of Volume Procedures for Johannesburg,
Durban,Cape Town, Pretoria and Port Elizabeth (includes corresponding
Graph/Chart) 184
- B. Market Analytics 185
- Table 99: Rest of World Recent Past, Current & Future Market
Analysis for Organ Transplantation by OrganType - Heart, Kidney, Liver,
Pancreas and Lung Independently Analyzed by Number of Proceduresfor Years
2009 through 2015 (includescorresponding Graph/Chart) 185
- Table 100: Rest of World Historic Review for Organ Transplantation by
Organ Type - Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed
by Numberof Procedures for Years 2003 through 2008(includes corresponding
Graph/Chart) 186
- Table 101: Rest of World 11-Year Perspective for Organ Transplantation
by Organ Type - Percentage Breakdownof Number of Procedures for Heart,
Kidney, Liver,Pancreas and Lung Markets for Years 2003, 2007 &2012
(includes corresponding Graph/Chart) 187
COMPETITIVE LANDSCAPE
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