Symbicort (Asthma) - Forecast and Market Analysis to 2023
|出版日期||內容資訊||英文 52 Pages
|Symbicort(氣喘):市場預測與分析 Symbicort (Asthma) - Forecast and Market Analysis to 2023|
|出版日期: 2014年08月31日||內容資訊: 英文 52 Pages||
GlobalData has released its new PharmaPoint Drug Evaluation report, "Symbicort (Asthma) - Forecast and Market Analysis to 2023". The asthma market saw very slow growth over the past decade, as it has become saturated with relatively efficacious standard therapies, such as short-acting beta-agonists (SABAs), inhaled corticosteroids (ICSs), inhaled corticosteroids and long-acting beta-agonists (ICS/LABAs), and leukotriene modifiers, and has also been facing increasing generic competition. However, the launch of seven novel targeted biologic agents and once-daily ICS and ICS/LABA therapies delivered by the next-generation inhalers will strongly drive the market growth over the next 10 years. The biologic agents will not only reshape the market growth, but will also mark the beginning of a new era of a personalized approach to asthma treatment. The realization that asthma is a very heterogeneous disease is highly reflected in the rich assortment of these targeted therapies in the late-stage pipeline.
Symbicort is an FDC of budenoside and formoterol fumarate developed by AstraZeneca. Budesonide is a synthetic corticosteroid with strong anti-inflammatory activity. It can bind to glucocorticoid receptors with high affinity and inhibit the secretion of mediators involved in asthma. Budesonide is marketed by AstraZeneca as a standalone product called Symbicort. Formoterol fumarate is a highly selective LABA. It acts by increasing cAMP, which, in turn, leads to relaxation of the bronchial smooth muscle.