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市場調查報告書

Tedatioxetine(重度憂鬱症)-預測與市場分析

Tedatioxetine (Major Depressive Disorder) - Forecast and Market Analysis to 2023

出版商 GlobalData 商品編碼 305489
出版日期 內容資訊 英文 58 Pages
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Tedatioxetine(重度憂鬱症)-預測與市場分析 Tedatioxetine (Major Depressive Disorder) - Forecast and Market Analysis to 2023
出版日期: 2014年05月30日 內容資訊: 英文 58 Pages
簡介

重度憂鬱症(MDD)是世界最常見的精神疾病之一。其市場競爭激烈,有超過30個產品上市中。在Eli Lilly的Cymbalta、大塚製薬/BMS的Abilify等主力產品專利即將到期,及Lundbeck/武田薬品工業的Brintellix等位於最終階段平台產品即將上市的當下,市場正在大大變化中。Tedatioxetine是由Lundbeck所開發的MDD治療藥。這是多重作用機制型抗憂鬱劑,前臨床實驗顯示其可抑制單胺轉運子上的再吸收,以增加單胺,或具有5-HT3及5-HT2C受體拮抗劑之作用。

本報告提供重度憂鬱症的治療藥物Tedatioxetine之調查分析,為您提供疾病概要和治療指南,競爭情形,產品資訊,銷售額預測等彙整資料。

第1章 目錄

第2章 簡介

第3章 疾病概要

  • 病因·病理生理學
    • 病因
    • 病理生理學
  • 分類
  • 症狀及亞型
  • 預後
  • QOL

第4章 疾病的管理

  • 症狀和治療概要

第5章 競爭評估

  • 概要

第6章 機會及未滿足需求

  • 概要
  • 更有效的藥物療法
  • 更佳副作用簡介
  • 效果快速的抗憂鬱效果
  • 個人化醫療的方法

第7章 開發平台分析

  • 概要
  • 臨床開發中的潛力藥物

第8章 Tedatioxetine (Lu AA24530)

  • 概要
  • 功效
  • 安全性
  • 給藥與處方
  • 臨床及市場上的潛在地位
  • SWOT分析
  • 預測

第9章 附錄

圖表

目錄
Product Code: GDHC430DFR

Major depressive disorder (MDD) is one of the most common psychiatric diseases worldwide. The MDD market is a crowded and competitive market, with more than 30 marketed products available for the treatment of patients with MDD. The depression market is about to enter a dynamic phase with imminent patent expiries for top selling products, such as Eli Lilly's Cymbalta, and Otsuka/BMS's Abilify, along with the recent launch of the multimodal antidepressant, Lundbeck/Takeda's Brintellix, in January 2014, and the potential introduction of seven promising late-stage pipeline products into the market during the forecast period, from 2013 to 2023.

Tedatioxetine (Lu AA24530) is being developed by Lundbeck for the treatment of MDD. It is a multimodal antidepressant and preclinical studies have shown that it acts as a monoamine enhancer with reuptake inhibition at monoamine transporters, as well as a 5-HT3 and 5-HT2C receptor antagonist (Lundbeck, press release, July 2, 2009).

Scope

  • Overview of Major depressive disorder, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
  • Detailed information on Tedatioxetine including product description, safety and efficacy profiles as well as a SWOT analysis.
  • Sales forecast for Tedatioxetine for the top eight countries from 2013 to 2023.
  • Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan and Australia.

Reasons to buy

  • Understand and capitalize by identifying products that are most likely to ensure a robust return
  • Stay ahead of the competition by understanding the changing competitive landscape for Major depressive disorder
  • Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
  • Make more informed business decisions from insightful and in-depth analysis of Tedatioxetine performance
  • Obtain sales forecast for Tedatioxetine from 2013-2023 in the top eight countries (the US, France, Germany, Italy, Spain, the UK, Japan and Australia)

Table of Contents

1. Table of Contents

  • 1.1 List of Tables
  • 1.2 List of Figures

2. Introduction

  • 2.1 Catalyst
  • 2.2 Related Reports
  • 2.3 Upcoming Related Reports

3. Disease Overview

  • 3.1 Etiology and Pathophysiology
    • 3.1.1 Etiology
    • 3.1.2 Pathophysiology
  • 3.2 Classification
  • 3.3 Symptoms and Subtypes of Major Depressive Disorder
  • 3.4 Prognosis
  • 3.5 Quality of Life

4. Disease Management

  • 4.1 Diagnosis and Treatment Overview
    • 4.1.1 Diagnosis
    • 4.1.2 Treatment Guidelines and Leading Prescribed Drugs
    • 4.1.3 Clinical Practice

5. Competitive Assessment

  • 5.1 Overview

6. Unmet Needs and Opportunities

  • 6.1 Overview
  • 6.2 More Effective Pharmacotherapies
    • 6.2.1 Unmet Needs
    • 6.2.2 Gap Analysis
    • 6.2.3 Opportunities
  • 6.3 More Favorable Side Effect Profiles
    • 6.3.1 Unmet Needs
    • 6.3.2 Gap Analysis
    • 6.3.3 Opportunities
  • 6.4 Rapid Onset of Antidepressant Effects
    • 6.4.1 Unmet Needs
    • 6.4.2 Gap Analysis
    • 6.4.3 Opportunities
  • 6.5 Personalized Treatment Approach
    • 6.5.1 Unmet Needs
    • 6.5.2 Gap Analysis
    • 6.5.3 Opportunities

7. Pipeline Assessment

  • 7.1 Overview
  • 7.2 Promising Drugs in Clinical Development

8. Tedatioxetine (Lu AA24530)

  • 8.1 Overview
  • 8.2 Efficacy
  • 8.3 Safety
  • 8.4 Dosing and Formulation
  • 8.5 Potential Clinical and Commercial Positioning
  • 8.6 SWOT Analysis
  • 8.7 Forecast

9. Appendix

  • 9.1 Bibliography
  • 9.2 Abbreviations
  • 9.3 Methodology
  • 9.4 Forecasting Methodology
    • 9.4.1 Diagnosed MDD Patients
    • 9.4.2 Percent of Drug-Treated Patients
    • 9.4.3 General Pricing Assumptions
    • 9.4.4 Generic Erosion
    • 9.4.5 Pricing of Pipeline Agents
  • 9.5 Physicians and Specialists Included in this Study
  • 9.6 About the Authors
    • 9.6.1 Analyst
    • 9.6.2 Therapy Area Directors
    • 9.6.3 Global Head of Healthcare
  • 9.7 About GlobalData
  • 9.8 Disclaimer

List of Tables

  • Table 1: Classification and Criteria of Major Depressive Disorder (DSM-IV) and Major Depressive Episode (ICD-10)
  • Table 2: Subtypes of Major Depressive Disorder
  • Table 3: Severity of Depressive Episodes according to ICD-10 and DSM-IV Diagnostic Criteria
  • Table 4: Treatment Guidelines for Major Depressive Disorder
  • Table 5: Most Prescribed Drugs for MDD by Class in the 7MM and Australia, 2013
  • Table 6: Leading Treatments for MDD, 2013
  • Table 7: Unmet Needs and Opportunities in MDD
  • Table 8: Comparison of Therapeutic Classes in Development for MDD, 2013
  • Table 9: Product Profile - Tedatioxetine
  • Table 10: Tedatioxetine SWOT Analysis, 2014
  • Table 11: Global MDD Sales Forecasts ($m) for Tedatioxetine, 2013-2023
  • Table 12: High-Prescribing Physicians (Non-KOLs) Surveyed, by Country

List of Figures

  • Figure 1: Overview of Targets of Antidepressant Action on Noradrenergic and Serotonergic Neurons
  • Figure 2: Disease Management Model for Major Depressive Disorder
  • Figure 3: Major Depressive Disorder Treatment Algorithm
  • Figure 4: MDD - Phase IIb-III Pipeline, 2014
  • Figure 5: Competitive Assessment of Late-Stage Pipeline Agents in MDD, 2013-2023
  • Figure 6: Clinical and Commercial Positioning of Tedatioxetine
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