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市場調查報告書

Cariprazine(精神分裂症治療藥):市場預測與分析

Cariprazine (Schizophrenia) - Forecast and Market Analysis to 2022

出版商 GlobalData 商品編碼 299183
出版日期 內容資訊 英文 60 Pages
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Cariprazine(精神分裂症治療藥):市場預測與分析 Cariprazine (Schizophrenia) - Forecast and Market Analysis to 2022
出版日期: 2014年02月28日 內容資訊: 英文 60 Pages
簡介

Cariprazine是比D3更有效的D3/D2的部分致效劑,目前正由Gedeon Richter(匈牙利)與Forest(美國)進行精神分裂症·躁鬱症·大憂鬱症性障礙治療藥的臨床實驗。Cariprazine雖然顯現出對D3受體最大的結合性,但對5-HT2C和H1、腎上腺素受體部位的效能則相當低。

本報告提供精神分裂症治療藥之一──Cariprazine的全球市場相關分析,提供精神分裂症概要和治療方法,Cariprazine的商品資訊(特色·功效·安全性等)和競爭力,競爭的企業·藥品概要,全球主要國家的市場販售額預測(今後10年份)等調查,並將結果概述為以下內容。

第1章 目錄

第2章 簡介

第3章 疾病概要

  • 病因與病情
    • 病因
    • 病理
  • 症狀

第4章 疾病的管理

  • 診斷
    • 主觀的評估
    • 疾病的分類
  • 治療方法概要
    • 治療精神分裂症相關的急性激越症狀
    • 精神分裂症的維持療法

第5章 競爭企業的評估

  • 概要
  • 競爭企業的策略性評估

第6章 市場機會及未滿足需求

  • 未滿足需求概要
    • 一般的認知度
    • 早期診斷·治療
    • 長效型·最尖端的藥物遞輸系統
    • 有效管理負面症狀及認知症狀
  • 差距分析
    • 長效型的藥物遞輸
    • 負面症狀·認知症狀的管理

第7章 開發平台評估

  • 概要
  • 初期階段的開發中產品評估
  • 新的治療方法
    • 負面症狀
    • 認知症狀
  • 長效型的藥物遞輸
  • 技術趨勢分析
  • 處於臨床實驗階段的主要醫藥品

第8章 關於Cariprazine

  • 概要
  • 功效
  • 安全性
    • 給藥·劑型方法
    • 臨床方面的潛在定位
    • 商業方面的潛在定位
    • 價格設定和醫療費給付
  • SWOT分析
  • 預測

第9章 附錄

圖表一覽

目錄
Product Code: GDHC366DFR

Schizophrenia is a persistent long-term brain disorder that causes severe, debilitating psychotic episodes. Its core symptoms, auditory or visual hallucinations, are often accompanied by fixed, false, and often paranoid beliefs, called delusions. These two features are often combined with learning and cognitive deficits. WHO experts have estimated that roughly 24 million people are affected by schizophrenia worldwide. While the arrival of atypical antipsychotics has greatly expanded pharmacologic treatment options over the past two decades, the current drug market does not treat the negative and cognitive symptoms that are associated with the disease. GlobalData expects that the growing popularity of long-acting injectable (LAI) antipsychotics, along with the arrival of novel treatments that achieve higher efficacy in negative- and cognitive-predominant patients, will serve to stimulate growth in the marketplace over the forecast period. Country-specific treatment recommendations and policy implementation will be an essential metric for determining future mental health services in the 7MM.

Cariprazine is a D3-preferring D3/D2 receptor partial agonist under development for the treatment of schizophrenia, bipolar mania, and major depressive disorder by Hungary-based Gedeon Richter and Forest. While maintaining highest affinity for D3 receptors, cariprazine also has low potency at 5-HT2C, H1, and adrenergic receptor sites.

Scope

  • Overview of Schizophrenia, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
  • Detailed information on Cariprazine including product description, safety and efficacy profiles as well as a SWOT analysis.
  • Sales forecast for Cariprazine for the top seven countries from 2012 to 2022.
  • Sales information covered for the US, France, Germany, Italy, Spain, the UK and Japan

Reasons to buy

  • Understand and capitalize by identifying products that are most likely to ensure a robust return
  • Stay ahead of the competition by understanding the changing competitive landscape for Schizophrenia
  • Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
  • Make more informed business decisions from insightful and in-depth analysis of Cariprazine performance
  • Obtain sales forecast for Cariprazine from 2012-2022 in the top seven countries (the US, France, Germany, Italy, Spain, the UK and Japan)

Table of Contents

1. Table of Contents

  • 1.1. List of Tables
  • 1.2. List of Figures

2. Introduction

  • 2.1. Catalyst
  • 2.2. Related Reports
  • 2.3. Upcoming Reports

3. Disease Overview

  • 3.1. Etiology and Pathophysiology
    • 3.1.1. Etiology
    • 3.1.2. Pathophysiology
  • 3.2. Symptoms

4. Disease Management

  • 4.1. Diagnosis
    • 4.1.1. Subjective Assessments
    • 4.1.2. Disease Subtypes
  • 4.2. Treatment Overview
    • 4.2.1. Treatment of Acute Agitation Associated with Schizophrenia
    • 4.2.2. Maintenance Treatment of Schizophrenia

5. Competitive Assessment

  • 5.1. Overview
  • 5.2. Strategic Competitor Assessment

6. Opportunity and Unmet Need

  • 6.1. Unmet Needs Overview
    • 6.1.1. Public Awareness
    • 6.1.2. Early Diagnosis and Treatment
    • 6.1.3. Long-Acting and Advanced Drug Delivery Systems
    • 6.1.4. Effective Management of Negative and Cognitive Symptom Domains
  • 6.2. Gap Analysis
    • 6.2.1. Long-Acting Drug Delivery
    • 6.2.2. Treatment of Negative and Cognitive Symptoms

7. Pipeline Assessment

  • 7.1. Overview
  • 7.2. Early-Stage Pipeline Assessment
  • 7.3. Novel Therapeutic Approaches
    • 7.3.1. Negative Symptoms
    • 7.3.2. Cognitive Symptoms
  • 7.4. Long-Acting Drug Delivery
  • 7.5. Technology Trends Analysis
  • 7.6. Key Drugs in Clinical Development

8. Cariprazine

  • 8.1. Overview
  • 8.2. Efficacy
  • 8.3. Safety
    • 8.3.1. Dosing and Formulation
    • 8.3.2. Potential Clinical Positioning
    • 8.3.3. Potential Commercial Positioning
    • 8.3.4. Pricing and Reimbursement
  • 8.4. SWOT Analysis
  • 8.5. Forecast

9. Appendix

  • 9.1. Bibliography
  • 9.2. Abbreviations
  • 9.3. Methodology
  • 9.4. Forecasting Methodology
    • 9.4.1. Diagnosis and Treatment Rates
    • 9.4.2. Adherence Rates
    • 9.4.3. General Pricing Assumptions
    • 9.4.4. Generic Erosion
    • 9.4.5. Pricing of Pipeline Agents
  • 9.5. Key Opinion Leaders
  • 9.6. About the Authors
    • 9.6.1. Author
    • 9.6.2. Reviewers
    • 9.6.3. Global Head of Healthcare
  • 9.7. About GlobalData
  • 9.8. Disclaimer

List of Tables

  • Table 1: Symptom Clusters of Schizophrenia
  • Table 2: Common Subjective Rating Scales Employed in Schizophrenia Diagnosis
  • Table 3: Development-Based Classification of Antipsychotic Drugs
  • Table 4: Receptor Binding Profiles of Atypical Antipsychotics
  • Table 5: Guidelines for the Treatment of Schizophrenia
  • Table 6: Leading Branded Treatments for Schizophrenia, 2013
  • Table 7: Strategic Competitor Assessment of the Marketed Products in Schizophrenia, 2014
  • Table 8: Unmet Needs - Current Level of Attainment
  • Table 9: Clinical Unmet Needs - Gap Analysis, 2013
  • Table 10: Technological Trends Analytic Framework in the Schizophrenia Pipeline, 2014
  • Table 11: Pipeline Candidates in Development for Schizophrenia, 2014
  • Table 12: Comparison of Novel Therapeutic Classes in Development for Schizophrenia, 2013
  • Table 13: Product Profile - Cariprazine
  • Table 14: Cariprazine SWOT Analysis, 2014
  • Table 15: Global Sales Forecast ($m) for Cariprazine, 2012-2022

List of Figures

  • Figure 1: Schizophrenia - Pipeline Drugs by Target, 2014
  • Figure 2: Competitive Assessment of Late-Stage Pipeline Agents in Schizophrenia, 2012-2022
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