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市場調查報告書

Neupro(帕金森氏症治療藥):市場預測與分析

Neupro (Parkinson's Disease) - Forecast and Market Analysis to 2022

出版商 GlobalData 商品編碼 217308
出版日期 內容資訊 英文 62 Pages
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Neupro(帕金森氏症治療藥):市場預測與分析 Neupro (Parkinson's Disease) - Forecast and Market Analysis to 2022
出版日期: 2014年03月31日 內容資訊: 英文 62 Pages
簡介

UCB所開發的Neupro,是透過穿皮貼片劑(貼片)供給rotigotine的藥劑,已核准為早期∼晚期突發性帕金森氏症的症候治療藥,也用於中至重度的不寧腿症候群(RLS)緩和藥。rotigotine是非雌激素D2·D3受體激動劑,具有對D2的選擇性(Chen et al., 2009)。此外也具有腎上腺素和血清素活性。

本報告提供帕金森氏症的治療藥之一──Neupro的全球市場相關分析,提供疾病概要和治療方法,競爭的企業·藥品概要,市場競爭概況,Neupro的商品資訊(特色·功效·安全性等),全球主要國家的市場販售額預測(今後10年份)等調查,並將結果概述為以下內容。

第1章 目錄

第2章 簡介

  • 本報告概要
  • 相關調查

第3章 疾病概要

  • 病因與病情
    • 病因
    • 病理生理學
    • 預測
    • QoL(生活品質)
  • 症狀

第4章 疾病管理

  • 概要
    • 診斷:The UK Brain Bank的評估標準
    • 治療指南與主要的處方藥
  • 治療方法概要
    • 多巴胺有作用之等級
    • 帕金森氏症的各階段治療方法
    • 其他治療選擇
  • 帕金森氏症的評估規模
    • 帕金森氏症統一規模(UPDRS)
    • Hoehn and Yahr的病期分類
    • 其他臨床評估方法

第5章 競爭企業的評估

  • 概要
  • 競爭企業的策略性評估
  • 多巴胺受體激動劑

第6章 關於Neupro(rotigotine貼布)

  • 概要
  • 功效
  • 安全性
  • SWOT分析
  • 未來預測

第7章 附錄

圖表一覽

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目錄
Product Code: GDHC393DFR

Parkinson's disease is a progressive condition that is characterized by bradykinesia, muscular rigidity, tremor, and postural instability. As the second most common neurodegenerative disorder, Parkinson's disease may affect individuals of any age but prevalence is increased with age and it is most common in the elderly. Dopaminergic therapies have been fairly effective in treating bradykinesia, but several unmet needs remain. Some needs will be met during the forecast period from 2012-2022, while others, such as the need for disease-modifying drugs, will remain. GlobalData expects that advancements will be made in levodopa administration and that four new molecular entities will be introduced to the market by 2022, these factors along with increased patient numbers from an aging population will drive the market during the forecast period.

Neupro, developed by UCB, delivers rotigotine by a transdermal patch. It is approved to treat the signs and symptoms of early- to advanced-stage idiopathic Parkinson's disease and used in moderate to severe restless legs syndrome. Rotigotine is a non-ergoline D2 and D3 receptor agonist with selectivity for D2 (Chen et al., 2009). It also has adrenergic and serotonergic activity.

Scope

  • Overview of Parkinson's disease, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
  • Detailed information on Neupro including product description, safety and efficacy profiles as well as a SWOT analysis.
  • Sales forecast for Neupro for the top eight countries from 2012 to 2022.
  • Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan and Brazil.

Reasons to buy

  • Understand and capitalize by identifying products that are most likely to ensure a robust return
  • Stay ahead of the competition by understanding the changing competitive landscape for Parkinson's disease
  • Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
  • Make more informed business decisions from insightful and in-depth analysis of Neupro performance
  • Obtain sales forecast for Neupro from 2012-2022 in the top eight countries (the US, France, Germany, Italy, Spain, the UK, Japan and Brazil).

Table of Contents

1. Table of Contents

  • 1.1. List of Tables
  • 1.2. List of Figures

2. Introduction

  • 2.1. Catalyst
  • 2.2. Related Reports

3. Disease Overview

  • 3.1. Etiology and Pathophysiology
    • 3.1.1. Etiology
    • 3.1.2. Pathophysiology
    • 3.1.3. Prognosis
    • 3.1.4. Quality of Life
  • 3.2. Symptoms

4. Disease Management

  • 4.1. Overview
    • 4.1.1. Diagnosis - The UK Brain Bank Criteria
    • 4.1.2. Treatment Guidelines and Leading Prescribed Drugs
  • 4.2. Treatment Synopsis
    • 4.2.1. Dopaminergic Therapy Classes
    • 4.2.2. Treatment of Parkinson's Disease by Stage
    • 4.2.3. Other Treatment Options
  • 4.3. Parkinson's Disease Assessment Scales
    • 4.3.1. Unified Parkinson's Disease Rating Scale (UPDRS)
    • 4.3.2. Hoehn and Yahr Clinical Staging
    • 4.3.3. Other Clinical Assessments

5. Competitive Assessment

  • 5.1. Overview
  • 5.2. Strategic Competitor Assessment
  • 5.3. Dopamine Agonists

6. Neupro (rotigotine transdermal patch)

  • 6.1. Overview
  • 6.2. Efficacy
  • 6.3. Safety
  • 6.4. SWOT Analysis
  • 6.5. Forecast

7. Appendix

  • 7.1. Bibliography
  • 7.2. Abbreviations
  • 7.3. Methodology
  • 7.4. Forecasting Methodology
    • 7.4.1. Diagnosed Parkinson's Disease Patients
    • 7.4.2. Percent Drug-Treated Patients
    • 7.4.3. General Pricing Assumptions
    • 7.4.4. Compliance Assumptions
    • 7.4.5. Individual Drug Assumptions
    • 7.4.6. Generic Erosion
  • 7.5. Physicians and Specialists Included in this Study
  • 7.6. About the Authors
    • 7.6.1. Author
    • 7.6.2. Global Head of Healthcare
  • 7.7. About GlobalData
  • 7.8. Disclaimer

List of Tables

  • Table 1: Symptoms of Parkinson's Disease
  • Table 2: UK Brain Bank Diagnostic Criteria
  • Table 3: Diagnosis and Treatment Guidelines for Parkinson's Disease
  • Table 4: Most Prescribed Drugs for Parkinson's Disease by Class in the Global Markets, 2014
  • Table 5: Dopaminergic Therapy in Parkinson's Disease
  • Table 6: UPDRS Clinical Assessment of Disease Severity
  • Table 7: Parkinson's Disease Assessment Scales Used in Clinical Trials
  • Table 8: Treatment of Motor Symptoms in Parkinson's Disease
  • Table 9: Leading Treatments for Parkinson's Disease, 2014
  • Table 10: Product Profile - Neupro
  • Table 11: Neupro SWOT Analysis, 2014
  • Table 12: Global Sales Forecasts ($m) for Neupro, 2012-2022

List of Figures

  • Figure 1: Overview - L-dopa Metabolism and Inhibitor Classes
  • Figure 2: Overview - Treatment of Motor Symptoms of Parkinson's Disease
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