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市場調查報告書

癌症治療用抗體及疫苗:交易動向及產業預測

Dealmaking and Industry Outlook: Therapeutic Antibodies and Vaccines for Cancer

出版商 Decision Resources, Inc.
出版日期 2009年04月 商品編碼 85587
內容資訊 英文 33 Pages
價格
US $ 3450 PDF by E-mail (Global License)


癌症治療用抗體及疫苗:交易動向及產業預測 是由出版商Decision Resources, Inc.在2009年04月所出版的。 這份英文市場調查報告書包含33 Pages 價格從美金3450起跳。

簡介

本報告書內容包括:癌症治療用抗體及疫苗市場分析、現在的市場動向、產業課題、近年來該領域中的企業購併、合作動向介紹、未來預測等。內容綱要摘記如下:

實施概要

癌症市場

癌症治療用抗體

  • 已上市的抗體
  • 後期開發階段的抗體

癌症疫苗

  • 疫苗技術
  • 臨床開發產品線

形成產業事件

  • 併用單株抗體治療
  • 面臨關鍵時刻的癌症疫苗製造商

近年來的交易動向及商業策略

  • 抗體相關
    • Lilly針對ImClone Systems的購併案
    • Roche針對Genentech的敵對性購併案
    • Merck & Co與Schering-Plough的計畫性合併
  • 癌症疫苗相關
    • GlaxoSmithKline及Innogenetics
    • Pfizer及Celldex Therapeutics
    • Merck Serono及Oncothyreon
    • 武田藥品工業及Cell Genesys
    • Oxford BioMedica及Sanofi-Aventis
    • Transgene及Roche

市場刺激因素:利用單株抗體的免疫療法

  • 增加適應症
  • 針對早期疾病的轉換
  • 生物標記
  • 生物學名藥
  • 成本
  • 併用標靶治療

市場刺激因素:癌症疫苗

未來預測

圖表

目錄

Abstract

Introduction

Targeted cancer therapies have achieved phenomenal growth, and many MAb-based immunotherapies are blockbusters or mega-blockbusters. This market success is due not only to these MAbs' ability to treat unmet need in many cancers but also to the high cost of immunotherapies and biologics in general. Competition is increasing as more companies move into this arena; also, biosimilars will soon enter markets. Meanwhile, the cancer vaccine market is signifi cantly behind the MAb-based market in terms of products on the market, a robust pipeline, and workable technologies, but researchers hold out hope for the eventual success of this emerging market segment.

Get the Answers You Need to Shape Your Strategy

  • Eli Lilly' s CEO John Lechleiter told investors that oncology is going to be a sustainable play for many years to come. What is the outlook for the oncology market? Why are new companies fl ooding targeted therapy markets?
  • Companies are looking to gain a foothold in biologics markets or to extend MAb franchises. What types of therapeutic cancer MAb deals have taken place in the last two years? What strategies are companies using?
  • The emerging cancer vaccine market is signifi cantly behind the therapeutic cancer MAb market. What is the key issue involved in developing cancer vaccines? What technologies are in development? What deals are being made?
  • Bristol-Myers Squibb' s CEO James M. Cornelius told investors that an ImClone acquisition was the next logical step in the company' s almost ten-year relationship with ImClone. Why did BMS want to acquire ImClone? What key factor played in Lilly' s successful bid and acquisition of ImClone?
  • Roche has transitioned its pharmaceutical business with a focus on specialty segments and biologics. What was involved in Roche' s eight-month struggle to take over Genentech? Why was the winning bid agreeable to both parties?
  • Schering-Plough' s CEO Fred Hassan said stunning and accelerating changes in the global macro environment are driving changes in the pharma industry. Why did Schering-Plough accept Merck & Co.' s offer for a reverse merger? What technologies were key to the merger strategy?

Scope

  • Therapeutic monoclonal antibodies: Late-stage pipeline, targets, gold standards, combination MAb therapies, engineered/optimized antibodies, next-generation antibodies, biosimilar market entry dates, patent expiry.
  • Cancer vaccines: Late-stage pipeline, marketed vaccines, vaccine technologies, troubled companies.

Table of Contents

  • Executive Summary
    • Strategic Considerations
    • Stakeholder Implications
  • Oncology Markets
  • Therapeutic Cancer Antibodies
    • Antibodies Already on the Market
    • Antibodies in Late-Stage Development
  • Cancer Vaccines
    • Vaccine Technologies
    • Clinical Development Pipeline
  • Industry-Shaping Events
    • Combination MAb Therapies Not As Obvious As Hoped
    • Some Cancer Vaccine Companies on the Brink
  • Recent Deals and Business Strategies
    • Antibody-Based Dealmaking
      • Lilly' s Acquisition of ImClone Systems
      • Roche' s Hostile Takeover of Genentech
      • Merck & Co.' s Planned Merger with Schering-Plough
    • Cancer Vaccine Dealmaking
      • GlaxoSmithKline and Innogenetics
      • Pfi zer and Celldex Therapeutics
      • Merck Serono and Oncothyreon
      • Takeda and Cell Genesys
      • Oxford BioMedica and Sanofi -Aventis
      • Transgene and Roche
  • Market Drivers - MAb-Based Immunotherapies
    • Additional Indications
    • Shifts to Earlier-Stage Disease
    • Biomarkers
    • Biosimilars
    • Cost
    • Combination Targeted Therapies
  • Market Drivers - Cancer Vaccines
  • Outlook

Tables

  • 1. Marketed Antibody Therapies for Oncology
  • 2. Select Antibody Therapies in Phase II or Phase III Development for Oncology
  • 3. Cancer Vaccines in Phase III Development or Later
  • 4. Select Combination Targeted Therapies in Development, 2008
  • 5. Dealmaking: Cancer Monoclonal Antibodies, 2007 and 2008
  • 6. Dealmaking: Select Cancer Vaccines, 2008
  • 7. Dealmaking: Biomarkers Driving the Development and Sale of Targeted Cancer Therapies, 2008
  • 8. Potential Biosimilar Entry Dates for Marketed Monoclonal Antibody-Based Immunotherapies
  • 9. Cost Comparison of Targeted Therapy Cancer Treatment in the Adjuvant and Advanced-Stage Settings

Figures

  • 1. Forecasted Growth Rate for the Oncology Market, 2007-2014
  • 2. Top Ten Companies in the Oncology Market, 2007 and 2014
  • 3. Targeted Monoclonal Antibody Therapies: Combined Treatment in Metastatic Colorectal Cancer
  • 4. Commercial Potential of Treating Early-Stage and Late-Stage Cancer
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