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市場調查報告書

藥物釋出支架市場動向

Drug-Eluting Stents: Can the Market Rebound from Recent Setbacks?

出版商 Decision Resources, Inc.
出版日期 2007年04月 商品編碼 51649
內容資訊 英文 17 Pages
價格
本報告書已不再販售

本報告已在2011年12月21日停止出版。

簡介

自從2002年開始利用以來,藥物釋出支架在冠狀動脈性心臟病治療中取代裸金屬支架,拿下九成左右的市場。將血管再度狹窄的風險降至最小是其成功拿下市場的主因。

專門於醫療產業相關廣泛調查的美國市調公司 Decision Resources Inc. 總公司:Massachusetts State),針對藥物釋出支架市場動向進行調查分析,並系統整理調查結果後出版報告書 "Drug-Eluting Stents: Can the Market Rebound from Recent Setbacks?"

本報告書內容包括:冠狀動脈性心臟病治療中支架的利用動向、市場領先企業、近年來的課題、新技術創新、未來市場發展前景預測等。內容綱要摘記如下:

實施概要

介紹

冠狀動脈性心臟病及支架的利用

  • 冠狀動脈性心臟病
  • 冠狀動脈性心臟病治療
  • 心臟支架利用

藥物釋出支架

  • 市場領先企業
  • Guidant的競爭

藥物釋出支架相關問題

藥物釋出支架的新興技術創新

  • medtronic的Endeabor Stent
  • Abbott的Xience、Boston Scientific的Promus
  • Conor Medsystems的Costar
  • Biosensor的BioMatrix

藥物釋出支架市場的未來發展前景

  • 成為商機的安全問題
  • 價格競爭時代的來臨
  • 可溶解性生物支架
  • 市場復甦

  • 冠狀動脈性心臟病及急性冠狀症候群的罹患率:2006年
  • 新興藥物釋出支架

  • 藥物釋出支架市場的里程碑
  • 支架嵌入、再度狹窄、血栓症
  • 全球Taxus及Cypher的銷售金額

目錄

Abstract

Introduction

A few years after their introduction in 2002, drug-eluting stents had all but replaced bare-metal stents in the treatment of coronary heart disease, capturing up to 90% of the market. Physicians favored the new stents primarily because of their ability to minimize the risk of restenosis associated with bare-metal stents. Recently, however, new safety concerns have begun to erode the market share of drug-eluting stents. The promise of next-generation drug-eluting stents that are beginning to emerge-including Medtronic' s Endeavor, expected to launch in the United States in late 2007, and Abbott' s Xience, currently in clinical trials in the United States and Japan-is likely to help the drug-eluting stent market rebound from its current low. However, lingering safety concerns and the possibility of competitive pricing may keep the market from achieving its earlier high.

Get the Answers You Need to Shape Your Strategy

  • The need to effectively compete with the next generation of drug-eluting stents has prompted the current market leaders-Johnson & Johnson and Boston Scientifi c-to acquire companies with next-generation stents in their pipelines. How do next-generation stents differ from currently available drug-eluting stents? Will the recent mergers of Boston Scientifi c and Guidant and Johnson & Johnson and Conor Medsystems help the market leaders to retain their market dominance?
  • Recent concerns that drug-eluting stents are associated with increased risk of late stent thrombosis arise from data on just two products-Boston Scientifi c' s Taxus stent and Cordis/Johnson & Johnson' s Cypher stent. What competitive opportunities does the potential for late stent thrombosis offer to manufacturers of other drug-eluting stents? How do current concerns about the risk of late stent thrombosis affect the outlook for Medtronic' s Endeavor stent, if it receives approval in the United States?
  • To acquire Guidant, Boston Scientifi c not only took on a heavy debt load, it also struck a deal with Abbott Laboratories that gave Abbott rights to Guidant' s Xience V DES platform. Was the decision to acquire Guidant a good strategic move for Boston Scientifi c? Will Boston Scientifi c' s privatelabel Xience stent, Promus, affect the company' s overall sales of drug-eluting stents?
  • Recent safety concerns about drug-eluting stents have dampened the early enthusiasm for this technology. How is the FDA likely to respond to the recent safety concerns about drug-eluting stents? Is the drug-eluting stent market likely to rebound from its recent fall?
  • In March 2007, Medtronic released two-year results from the largest and longest drug-eluting stent clinical trial program to date. What advantages does Medtronic' s Endeavor stent offer over existing drug-eluting stents? How is the availability of the Endeavor stent likely to affect the market share of the Taxus and Cypher stents?

Scope

  • Use of stents in coronary heart disease: the limitations of “balloon” angioplasty; introduction of bare-metal stents; the advantages and mechanisms of drug-eluting stents.
  • Market leaders: Boston Scientifi c' s Taxus versus Cordis/Johnson & Johnson' s Cypher; the takeover battle for Guidant.
  • Recent concerns: the risk of late stent thrombosis; discontinuation of antiplatelet therapies; the effects of drug-eluting stents on coronary collateral functions; FDA conclusions.
  • Emerging innovations: new stents from Medtronic, Abbott/Boston Scientifi c, Conor Medsystems, and Biosensors.
  • Outlook: upcoming diffi culties with regulatory approval; potential growth of antiplatelet medications; the emergence of competitive pricing; future competition from bioabsorbable stents.

Table of Contents

  • Executive Summary
    • Strategic Considerations
    • Stakeholder Implications
  • Introduction
  • Coronary Heart Disease and Stent Use
    • Coronary Heart Disease
    • Treatment for Coronary Heart Disease
    • The Use of Cardiac Stents
  • The Drug-Eluting Stent Market
    • Market Leaders
    • The Battle for Guidant
  • Concerns Arise over Drug-Eluting Stents
  • Emerging Innovations in Drug-Eluting Stents
    • Medtronic' s Endeavor Stent
    • Abbott' s Xience/Boston Scientifi c' s Promus
    • Conor Medsystems' Costar
    • Biosensors' BioMatrix
  • The Outlook for the Drug-Eluting Stent Market
    • Safety Concerns Create Commercial Opportunities
    • The Emergence of Competitive Pricing
    • Bioabsorbable Stents
    • Market Rebound

Tables

  • 1. Prevalence of Coronary Heart Disease and Acute Coronary Syndrome, 2006
  • 2. Emerging Drug-Eluting Stents

Figures

  • 1. Milestones in the Drug-Eluting Stent Market
  • 2. Stent Implantation, Restenosis, and Thrombosis
  • 3. Worldwide Sales of Taxus Versus Cypher
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