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市場調查報告書

癌症免疫概要

Immuno-Oncology Overview

出版商 Datamonitor Healthcare 商品編碼 342050
出版日期 內容資訊 英文 108 Pages
商品交期: 最快1-2個工作天內
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癌症免疫概要 Immuno-Oncology Overview
出版日期: 2015年06月12日 內容資訊: 英文 108 Pages
簡介

癌症免疫,是癌症研究最有希望且成長快速的領域之一,也成為授權契約、收購相關最活躍的領域之一。

本報告以癌症免疫及各種癌症免疫級為主題,提供3位關鍵意見領袖的採訪、 BioMedTracker的開發平台資料,Pharma & MedTech Business Intelligence 及 Medtrack的契約資訊等。

目錄

  • 癌症免疫概要
  • 採訪
  • CTLA-4
  • PD-1/PD-L1
  • TIM3
  • LAG3
  • OX40
  • CD40
  • CAR-T 細胞療法
  • T-細胞受體遺傳基因療法
  • 樹狀細胞療法
  • CSF1R
  • IDO
  • CEA
目錄
Product Code: DMKC0139837

This is an overview of the field of immuno-oncology and the various immuno-oncology classes. Immuno-oncology is one of the most promising and fastest growing areas of cancer research, as well as one of the most active areas in terms of licensing deals and acquisitions.

Highlights

Datamonitor Healthcare anticipates that the PD-1/PD-L1 class will gain approvals for multiple tumor types, and that this class will be the most commercially successful immuno-oncology class over the next 10 years. As monotherapies, PD-1 inhibitors will become the first-line treatment of choice in melanoma, and they are also likely to gain further approvals for a wide variety of cancers.

CAR-T cell therapy early clinical results are extremely promising. The leading CD19-targeted CAR-T treatments from Novartis, Juno, and Kite all provide response rates hovering around 90% for patients with multiply relapsed or refractory acute lymphoblastic leukemia.

Expectations for cancer vaccines have diminished after multiple failures. In theory, a cancer vaccine treatment should be able to strengthen the immune response against a cancer and help to prevent it from recurring. In practice, a series of Phase III studies investigating cancer vaccines have failed to meet their primary endpoints, and the potential future role of this class has diminished with each trial failure.

Methodology

Three key opinion leaders were interviewed for this analysis, with the full interviews being transcribed. Pipeline data were provided by BioMedTracker, and deals information was provided by Pharma & MedTech Business Intelligence and Medtrack.

Table of Contents

  • Immuno-oncology overview
  • Interviews
  • CTLA-4
  • PD-1/PD-L1
  • TIM3
  • LAG3
  • OX40
  • CD40
  • CAR-T cell therapy
  • T-cell receptor gene therapy
  • Dendritic cell therapy
  • CSF1R
  • IDO
  • CEA
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