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市場調查報告書

憂鬱症:針對二線患者的新一代產品競爭

Product Profiles: Depression - Next generation vies for second-line patients

出版商 Datamonitor
出版日期 2011年11月 商品編碼 203196
內容資訊 英文 Pages: 221
價格
本報告書已不再販售

本報告已在2012年03月16日停止出版。

更改為出版

Product Profiles: Depression - Next generation vies for second-line patients
出版日期 : 2012年01月
商品編碼: 234121

簡介

因為目前領導市場的憂鬱症品牌藥,專利在2012~2015年主要市場上將會到期,於是市場上的競爭便愈加激烈。為了克服這個嚴苛的環境,新的抗憂鬱症藥物就必須和現行的單胺再攝取抑制劑有非常大的區別不可。

本報告提供為了治療憂鬱症的上市品牌和開發平台藥物的趨勢分析,有關臨床及商業特性的相關比較分析,最新臨床實驗資料,上市品牌今後的預測和憂鬱症治療的未滿足需求等資料,為您概述為以下內容。

概要

摘要整理

市場定義和概要

上市產品簡介

  • Lexapro
    • 藥物簡介
    • 發展概要
    • SWOT分析
    • 產品定位
    • 醫生的見解
    • 臨床·商業的特性
  • Effexor XR
  • Pristiq
  • Cymbalta
  • Valdoxan
  • Abilify
  • Seroquel XR
  • Oleptro
  • 其他上市藥物

產品線簡介

  • Viibryd
    • 藥物簡介
    • 發展概要
    • SWOT分析
    • 未滿足需求的滿足度
    • 臨床·商業的特性
  • Lu AA21004
  • TC-5214
  • Levomilnacipran
  • Edivoxetine
  • Vyvanse
  • 其他開發中的藥物

參考資訊

附錄

目錄

Description

Introduction

Patents for the current market-leading depression brands are due to expire in the major markets between 2012 and 2015, by which time competition in the market will be at its fiercest. In order to flourish in this harsh environment, new antidepressants must be sufficiently differentiated from conventional monoamine neurotransmitter reuptake inhibitors.

Features and benefits

  • Understand Datamonitor's independent appraisal of marketed brands and key pipeline agents indicated for treating depression.
  • Illustrate how pipeline and marketed drugs compare to one another in terms of clinical and commercial attributes.
  • Review important clinical developments for key pipeline agents with analysis of the latest clinical trial data.
  • Understand how marketed brands are positioned in the depression treatment algorithm and how they are perceived by psychiatrists.
  • Determine to what extent future therapies satisfy the main clinical unmet needs in depression treatment.

Highlights

  • Datamonitor's physician survey reveals that psychiatrists perceive Forest's and Lundbeck's selective serotonin reuptake inhibitor Lexapro (escitalopram) to be the leading depression treatment, with a superior efficacy and tolerability profile to other antidepressant brands.
  • TC-5214 (Targacept/AstraZeneca) and several pipeline antidepressants are poised to usurp Lexapro, following its loss of market exclusivity, and become the most attractive depression brands.
  • Forest's Viibryd (vilazodone) has the hallmarks of a new blockbuster - a novel mode of action, favorable tolerability, and the marketing prowess of Forest. Viibryd will be well received due to its good tolerability, although commercial success comparable to Lexapro will be unattainable as more innovative competitor drugs near the US market.

Your key questions answered

  • What is the gold-standard drug for depression?
  • How are marketed brands positioned in the depression treatment algorithm?
  • Which are the most likely drugs to emerge from the pipeline and how will they impact the way depression is treated?
  • What are the comparative strengths and weaknesses of the key depression brands and pipeline candidates?

TOC

Executive Summary

  • Update details: October 2011
  • Strategic scoping and focus
  • Datamonitor key findings
  • Related reports

OVERVIEW

  • Catalyst
  • Summary

MARKET DEFINITION AND OVERVIEW

  • Product overview

MARKETED PRODUCT PROFILES

  • Lexapro (escitalopram; Forest/Lundbeck)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Product positioning
    • Physicians' perceptions of Lexapro
    • Clinical and commercial attractiveness
  • Effexor XR (venlafaxine extended release; Pfizer)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Pristiq (desvenlafaxine; Pfizer)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Product positioning
    • Physicians' perceptions of Pristiq
    • Clinical and commercial attractiveness
  • Cymbalta (duloxetine; Eli Lilly/Shionogi)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Product positioning
    • Physicians' perceptions of Cymbalta
    • Clinical and commercial attractiveness
  • Valdoxan (agomelatine; Servier)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Product positioning
    • Physicians' perceptions of Valdoxan
    • Clinical and commercial attractiveness
  • Abilify (aripiprazole; Bristol-Myers Squibb/Otsuka)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Product positioning
    • Physicians' perceptions of Abilify
    • Clinical and commercial attractiveness
  • Seroquel XR (quetiapine extended release; AstraZeneca)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Product positioning
    • Physicians' perceptions of Seroquel XR
    • Clinical and commercial attractiveness
  • Oleptro (trazodone extended release; Labopharm)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Other marketed drugs for depression
    • Remeron (mirtazapine; Merck & Co./Meiji Seika)

PIPELINE PRODUCT PROFILES

  • Viibryd (vilazodone; Forest)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Satisfaction of unmet needs
    • Clinical and commercial attractiveness
  • Lu AA21004 (Lundbeck/Takeda)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Satisfaction of unmet needs
    • Clinical and commercial attractiveness
  • TC-5214 (Targacept/AstraZeneca)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Satisfaction of unmet needs
    • Clinical and commercial attractiveness
  • Levomilnacipran (F2695; Forest/Pierre Fabre)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Satisfaction of unmet needs
    • Clinical and commercial attractiveness
  • Edivoxetine (LY2216684; Eli Lilly)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Satisfaction of unmet needs
    • Clinical and commercial attractiveness
  • Vyvanse (lisdexamfetamine; Shire)
    • Drug profile
    • Development overview
    • SWOT analysis
    • Satisfaction of unmet needs
    • Clinical and commercial attractiveness
  • Other drugs in development for depression
    • CPI-300 (bupropion; IntelGenx)
    • AZD6765 (AstraZeneca)
    • BCI-224 (sabcomeline; BrainCells)
    • BCI-540 (coluracetam; BrainCells/Mitsubishi Tanabe)
    • BCI-952 (melatonin and buspirone; Brain Cells)
    • BMS-820836 (Bristol-Myers Squibb/AMRI)
    • Cariprazine (RGH-118; Forest/Gedeon Richter/Mitsubishi Tanabe)
    • Cimicoxib (UR-8880; Affectis Pharmaceuticals/Palau Pharma)
    • CP-601,927 (Pfizer)
    • EB-1010 (Euthymics Bioscience)
    • GLYX-13 (Naurex)
    • JNJ-26489112 (Johnson & Johnson)
    • Lu AA24530 (Lundbeck/Takeda)
    • OPC-34712 (Otsuka)
    • Orvepitant (GSK823296; GlaxoSmithKline)
    • PNB-01 (pipamperone and citalopram; PharmaNeuroBoost)
    • RG7090 (Roche)
    • SA4503 (cutamesine; M's Science)
    • Serdaxin (clavulanic acid; Rexah
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