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市場調查報告書
蛋白質體學的現況及未來發展方向
Proteomics: Current State and Future Directions
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蛋白質體學的現況及未來發展方向 是由出版商Insight Pharma Reports在2006年09月所出版的。
這份英文市場調查報告書包含65 pages 價格從美金2500起跳。
因基因領域相關調查而獲全球高度評價的美國市調公司 Insight Pharma Reports （總公司：麻薩諸塞州），針對蛋白質體學的現況及未來發展方向進行詳細的調查分析，並出版調查報告書 "Proteomics: Current State and Future Directions" 。
本報告書內容包括：蛋白質的分離、檢測、定量相關主要技術的好處及壞處分析，以及主要課題、發展及進入市場中的解決方案、最重要的研究計畫、產品的市場發展、企業介紹、企業間合作/合併趨勢等分析，包含圖表共計75頁的內容綱要摘記如下：
第1章 介紹：蛋白質體分析技術的現況
第2章 蛋白質體分析技術的發展經過
第3章 蛋白質體學的研究課題
第4章 現有的技術
- 蛋白質分離/樣本濃縮
- 液體層析儀
- 除去蛋白質
- 質量編碼標籤
第5章 定量分析法比較
- 蛋白質認定及定量
- 抗體/蛋白質陣列應用
- 蛋白質認定及定量、抗體
- 蛋白質間相互作用(Protein-Protein Interaction:PPI)
第6章 技術課題
第7章 主要研究方法
第8章 主要產品的市場發展
- Beckman Coulter
- Sigma-Aldrich
- Cambrex
- Serva Electrophoresis
- PerkinElmer
- Thermo Electron
- Sigma-Aldrich
- Agilent Technologies
- Bruker Daltonics
- KREATECH
- Axela Biosensors
- Syngene
- Sigma-Aldrich
第9章 主要企業間合作及合併
- CombiMatrix Biodesign Institute
- Caprion/ICOS
- Affibody/Agilent
- PerkinElmer/Agilix
- Applied Biosystems/Invitrogen
- PerkinElmer/Luminex
第10章 專家訪談：蛋白質體學的現況及未來發展方向
- Roger Brent, PhD
- Gilbert S. Omenn, MD, PhD
- James R. Heath, PhD
第11章 企業介紹
- Biacore
- Bio-Rad Laboratories
- Invitrogen
- Luminex
- Thermo Electron
附錄
圖表
Abstract
Proteomics is a rapidly evolving field that is rife with commercial
opportunities as the technology achieves ever higher throughput at lower cost
and greater sensitivity. Proteomics: Current State and Future Directions is a
new CHA Advances report that delivers an up-to-the-minute assessment of the
state of proteomics and its applications in drug and biomarker discovery. The
report provides insight into:
- Strengths and weaknesses of the leading technologies for protein
separation, detection, and quantification - with an emphasis on
high-throughput approaches
- The fundamental challenge posed by the vast dynamic range among protein
concentrations, and the potential solutions in development and entering the
market
- Recent applications of proteomics to discover biomarkers for preeclampsia,
and for neonatal ureteropelvic junction, and to differentiate between
diagnosis of ALS and Parkinson' s disease
- Technologies such as mass spectrometry, antibody-bearing chips, and
solution array multiplexing to address the challenge of detecting
low-abundance proteins
- The most significant research initiatives and recent product
introductions, company profiles, and the major deals and M&As that are shaping
the proteomics landscape
Table of Contents
SECTION 1
- Introduction: The Current State of Proteomics Technology
SECTION 2
- A Brief History of Proteomics Technology
SECTION 3
- General Overview of Proteomics Research Challenges
SECTION 4
- Current Technologies
- Protein Separation/Sample Enrichment
- Liquid Chromatography
- Protein Removal
- Mass-coded Labeling
SECTION 5
- Research Comparing Quantification Methods
- Protein Identification and Quantification
- Mass Spectrometry
- Common MS Instrument Types
- Antibody/Protein Array Applications
- Protein Indentification and Quantification, Antibodies
- Protein-Protein Interaction
SECTION 6
- Technical Challenges
- Dynamic Range
- Albumin Removal
SECTION 7
- Selected Research Methods Reports
- Protein microarrays
- Sample Complexity
- Multiphoton Detection
SECTION 8
- Selected Product Introductions
- Beckman-Coulter
- Sigma-Aldrich
- Cambrex
- Serva Electrophoresis
- PerkinElmer
- Thermo Electron
- Sigma-Aldrich
- Agilent Technologies
- Bruker Daltonics
- KREATECH
- Axela Biosensors
- Syngene
- Sigma-Aldrich
SECTION 9
- Selected Deals and Mergers
- Combi Matrix/Biodesign Institute
- Caprion/ICOS
- Affibody/Agilent
- PerkinElmer/Agilix
- Applied Biosystems/Invitrogen
- PerkinElmer/Luminex
SECTION 10
- Expert Interviews: Current State and Future Directions
- Roger Brent, PhD
- Gilbert S. Omenn, MD, PhD
- James R. Heath, PhD
SECTION 11
- Selected Company Profiles
- BiaCore
- BioRad
- Invitrogen
- Luminex
- Thermo Electron
APPENDIX
- CHA Advances - 2006 Proteomics Survey
References
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