本報告已在2012年03月19日停止出版。
更改為出版
Mesenchymal Stem Cells - Advances & Applications
出版日期 : 2012年04月
商品編碼: 234291
全球包含間葉系幹細胞之研究活動、科學出版率、專利申請等，於2008∼2009年增加了58％，2009∼2010年則急速增加至112％，間葉系幹細胞無疑是幹細胞研究中發展最快之領域。
本報告為，匯整間葉系幹細胞研究市場趨勢及最終用戶關注、需求、近年產品開發及今後發展等，以下列之摘要形式闡述。
第1章 概要
第2章 資訊來源
第3章從間葉系幹細胞衍生之細胞類型
第4章 應用
- 應用基礎研究
- 造血細胞
- 基因轉移應用
- 細胞治療應用
- 組織工程所需之3D支架間葉系幹細胞利用
- 藥物傳遞應用：作為抗癌藥物載體之間葉系幹細胞工程
- 藥物篩選
- 免疫效應細胞對間葉系幹細胞產生之抑製作用
第5章 應優先之應用
第6章 提供研究人體間葉系幹細胞產品之企業
第7章 提供研究老鼠間葉系幹細胞產品之企業
第8章 間葉系幹細胞研究活動分析
第9章 市場趨勢分析
第10章 作為藥物發現工具之間葉系幹細胞
- 開發幹細胞毒性篩選平台之企業
- 老鼠間葉系幹細胞潛在藥物篩選之優點
第11章 間葉系幹細胞研究之無血清補充
第12章 潛在實驗室、客戶
第13章 最終用戶偏好
第14章 研發產品之機會及建議
第15章 結論
Abstract
DESCRIPTION (Summary)
This is an expanded and updated report that includes:
- 55 New Pages of Material
- Charts, Timelines, Metrics and Financials Updated for 2011
- 5-Year Projection Data Spanning 2011-2016
- Expanded Competitive Environment Analysis
- New Section Presenting End-User Preferences (Scientist Panel)
Overview:
Analysis of global grant activity, scientific publication rates, and patent
applications reveal that research activity involving mesenchymal stem cells
increased 58% year-over-year from 2008 to 2009, and 112% from 2009 to 2010. Of
most interest is that this rate of increase is projected to accelerate in
2011, making mesenchymal stem cells the fastest growing area of stem cell
research.
BioInformant has been following the mesenchymal stem cell market since it was
a minor market trend. As a result of escalating demand for MSC research,
research tools and therapeutic solutions, BioInformant launched a broadly
expanded version of the market report, “Mesenchymal Stem Cells,
Advances & Applications,” published January 2011.
Highlights of the publication include:
- Detailed characterization of the market, emphasizing statistical trend
assessment
- Exploration of recent product evolution and projected directions for
development
- Data on end-user interests, needs and technical preferences (Scientist
Panel)
- Overview of Therapeutic Progress
- Insight into Future Applications
- Detailed Evaluation of Profit Opportunities
- And Much More....
The report explores why no other stem cell type has experienced comparable
demand increase among researchers. Is there a momentum effect? Are
fundamentals driving the trend? Most importantly, what profit opportunities
does this trend represent?
The timing of this report is designed to assist companies with annual planning
and strategic decision-making to make 2011 a profitable year.
Table of Contents
I. Abstract
II. Overview
- A. Definition
- B. Alternative Names and Nomenclature
- C. Criteria for Identifying
- 1. Physical Characteristics
- 2. Functional Attributes
- D. Benefits Relative to Other Stem Cells
III. Isolation Sources
IV. Cell Types Derived from MSCs
V. Applications
- A. Basic Research Applications
- 1. Directed Differentiation of MSCs into Intra-Mesenchymal Lineages
- 2. Directed Differentiation of MSCs into Extra-Mesenchymal Lineages
- B. Supporting Hematopoietic Cells
- C. Gene Transfer Applications
- D. Cell Transplantation for Site-Specific Repair
- 1. Overview
- 2. Major Applications
- a. Osteogenic Repair
- b. Myogenic and Myocardial Repair
- c. Neural Repair
- d. Pancreatic Repair
- E. Topical Therapy and Use of MSCs in Wound Healing
- F. Use of MSC in 3-D Scaffolds for Tissue Engineering Applications
- G. Drug Delivery Applications: Engineered MSCs as specific carriers
of anti-cancer drugs
- H. Drug Screening
- I. MSC-mediated Inhibition of Immune Effector Cells
VI. Application Priorities
- A. Overall
- B. By Segment
- 1. Academic
- 2. Biotechnology
- 3. Pharmaceutical
VII. Companies Offering Human MSC Research Products
- A. Abcam
- B. BD Biosciences
- C. Celprogen
- D. Cyagen Biosciences (China only)
- E. Invitrogen
- F. LGC Standards/ATCC
- G. Lonza
- H. Millipore
- I. Miltenyi Biotec
- J. PAA - The Cell Culture Company
- K. PromoCell
- L. SA Biosciences
- M. ScienCell Research Laboratories
- N. Stem Cell Technologies
- O. Thermo Scientific
- P. R&D Systems
VIII. Companies Offering Rodent MSC Research Products
Eight companies offer rat MSC products: Cell Applications, Celprogen, Cyagen
Biosciences, Genlantis, Millipore, Miltenyi Biotec, ScienCell Research
Laboratories, and Trevigen.
However, five were profiled in the previous section, leaving three to profile
below as limited providers of rat MSC products.
- A. Abcam
- B. BD Biosciences
- C. Celprogen
IX. Analysis of MSC Research Activity
- A. By Tissue Source of Origin
- B. By Clinical Application
- C. By Species Source
- D. By Geographical Region
X. Market Trend Analysis
- A. Scientific Publication Rate Analysis
- 1. Historical 10-Year Analysis
- 2. Future Five-Year Projection
- B. Grant Trend Rate Analysis
- 1. Historical 10-Year Analysis
- 2. Future Five-Year Projection
- C. Patent Analysis
XI. Mesenchymal Stem Cells as Tools for Drug Discovery
- A. Companies Developing Toxicology Screening Platforms for Stem
Cells
- B. Potential Drug Screening Advantages of Rat MSCs
- 1. Acquisition, Handling, and Differentiation Advantages
- 2. Genetic Manipulation of MSCs
- 3. Potential for Genetically Engineered MSC Reporter Lines
XII. Serum Free Supplements for Use in MSC Research
- A. Invitrogen, Inc.
- B. Celprogen
- C. Millipore, Inc.
- D. Stem Cell Technologies
- E. U.S. Patent 7109032: Serum-free medium for mesenchymal stem
cells (Genoa, IT)
XIII. End-User Preferences (Scientist Panel)
- A. Source Preference
- B. Species Preference
- C. MSC Product Preferences
- D. Most-Commonly Used MSC Antibodies
- E. Common Terms Used for Online Product Search
XIV. Research Product Opportunities & Suggestions
- A. Rat MSCs Derived from Synovium
- B. Novel MSC Differentiation Kits
- C. Mesenchymal Stem Cell Expansion Media
- D. Antibodies to Mesenchymal Stem Cell Markers
- E. Mesenchymal Growth Factors
- F. Monoclonal Antibodies and Kits for Phenotyping MSCs
- G. Chips for MicroArray Analysis of Gene Expression in MSCs
XV. Potential Labs/Customers
- A. By Research Area:
- 1. General MSC Research Labs
- 2. Osteogenic-Focused Research Labs
- 3. Myogenic and Myocardial-Focused Research Labs
- 4. Adipogenic-Focused Research Labs
- 5. Neuronal-Focused Research Labs
- 6. Immunology-Focused Research Labs
- B. By Industry Segment
- 1. Commercial Labs
- 2. NIH Labs
XVI. Conclusions
