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市場調查報告書

細胞凋亡,癌症疫苗,Protein Kinase抗化劑:藥物開發策略分析

Triple Analysis: Apoptosis, Cancer Vaccines and Protein Kinase Inhibitors

出版商 BioSeeker Group AB
出版日期 2012年05月 商品編碼 227357
內容資訊 英文 5216 Pages
價格
US $ 5175 PDF by E-mail (Single User License)


細胞凋亡,癌症疫苗,Protein Kinase抗化劑:藥物開發策略分析 是由出版商BioSeeker Group AB在2012年05月所出版的。 這份英文市場調查報告書包含5216 Pages 價格從美金5175起跳。

簡介

本報告以癌症治療藥開發策略上細胞凋亡,癌症疫苗及Protein Kinase抗化劑的機制、目標、影響領域為焦點,彙整各種的藥劑目標策略,化合物策略競爭基準,開發平台及最佳投資組合計劃等資料,為您概述為以下內容。

第1章 細胞凋亡

  • 本報告的範圍
  • 為達成最高治療效果及投資報酬率的治療目標檢討
  • 新藥的上市:細胞凋亡治療開發平台上指定的藥劑目標是否成熟,是否有特色,臨床評估如何
  • 使用中的化合物策略:細胞凋亡藥物的各類型化合物的競爭基準
  • 細胞凋亡的癌適應症症狀選擇
  • 最佳投資組合計劃:細胞凋亡開發平台的競爭基準
  • 藥品目錄
  • 企業目錄
  • 圖表

第2章 癌症疫苗

  • 本報告的範圍
  • 為達成最高治療效果及投資報酬率的治療目標檢討
  • 新藥的上市:各開發階段的癌症疫苗治療藥劑目標策略
  • 使用中的化合物策略:各化合物策略競爭基準
  • 癌症疫苗的癌適應症症狀選擇
  • 開發平台及最佳投資組合:癌症疫苗開發平台的競爭基準
  • 免責聲明
  • 藥品目錄
  • 企業目錄
  • 圖表

第3章 Protein Kinase抗化劑

  • 本報告的範圍
  • 為達成最高治療效果及投資報酬率的治療目標檢討
  • 新藥的上市:Protein Kinase抗化劑開發平台上指定的藥劑目標是否成熟,是否有特色,臨床評估如何
  • 使用中的化合物策略:各類型化合物的競爭基準
  • Protein Kinase抗化劑的癌適應症症狀選擇
  • 最佳投資組合計劃:Protein Kinase抗化劑開發平台的競爭基準
  • 藥品目錄
  • 企業目錄
  • 圖表

目錄

Abstract

Product Description

This triple analysis focuses on cancer drug development strategies by mechanism/target/effect of Apoptosis, Cancer Vaccines and Protein Kinase Inhibitors. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.

Below is a short synopsis of each part included in this report:

Part I: Apoptosis

The apoptotic cancer drug report part comprises defined and up to date development strategies for 234 drugs in oncology within the portfolio of 158 companies world-wide, from Ceased to Marketed. The report extensively analyses their 181 identified drug targets, organized into 157 drug target strategies, and assesses them in 69 cancer indications.

Part II: Cancer Vaccines

The cancer vaccine report part comprises defined and up to date development strategies for 155 cancer vaccine drugs within the portfolio of 99 investigators, from Ceased to Marketed. This part extensively analyses their 94 identified drug targets, organized into 91 drug target strategies, and assesses them in 42 different cancer indications.

Part III: Protein Kinase Inhibitors

The protein kinase report comprises defined and up to date development strategies for 409 protein kinase drugs (990 projects) within the portfolio of 160 investigators, from Ceased to Marketed. This report part extensively analyses 133 identified targets of protein kinase drugs, organized into 200 drug target strategies, and assesses them in 57 different cancer indications.

The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies' pipeline and portfolio planning (PPP) in cancer by:

  • Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
  • Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug's properties
  • Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
  • Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
  • Supporting development of integrative molecule, pathway and disease area strategies
  • Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment

This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.

Table of Contents

Key Topics Covered:

Part I: Apoptosis

  • 5.1 The Scope of this Report
  • 6 Consider the Therapeutic Target Among Apoptotic Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (181 Drug Targets)
  • 7 Emerging New Products to Established Ones: Drug Target Strategies of Apoptotic Drugs in Oncology by their Highest Stage of Development (157 Drug Target Strategies and 234 Drugs)
  • 8 Compound Strategies at Work: Competitive Benchmarking of Apoptotic Cancer Drugs by Compound Strategy(7 Compound Strategies)
  • 9 Selecting Indication for Apoptotic Drugs in Oncology (69 Cancer Indications)
  • 10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Apoptotic Drug Pipeline in Oncology by Investigator (158 Investigators and 234 Drugs)
  • Disclaimer
  • 11 Drug Index
  • 12 Company Index
  • Figures: Includes 7 Figures
  • Tables: Includes 315 Tables
  • Total Number of Pages: 1,617

Part II: Cancer Vaccines

  • 5.1 The Scope of this Report
  • 6 Consider the Therapeutic Target Among Cancer Vaccine Drugs for the Highest Therapeutic Outcome and Return on Investment (94 Drug Targets)
  • 7 Emerging New Products to Established Ones: Drug Target Strategies of Cancer Vaccine Drugs by their Highest Stage of Development (91 Drug Target Strategies and 155 Cancer Vaccine Drugs)
  • 8 Compound Strategies at Work: Competitive Benchmarking of Cancer Vaccine Drugs by Compound Strategy (7 Compound Strategies)
  • 9 Selecting Cancer Indications for Cancer Vaccine Drugs (42 Cancer Indications)
  • 10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Cancer Vaccine Drug Pipeline by Investigator (99 Investigators)
  • 11 Disclaimer
  • 12 Drug Index
  • 13 Company Index
  • Figures: Includes 6 Figures
  • Tables: Includes 205 Tables
  • Total Number of Pages: 659

Part III: Protein Kinase Inhibitors

  • 5.1 The Scope of this Report
  • 6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (133 Drug Targets)
  • 7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Profiles Identified in the Cancer Protein Kinase Therapeutic Pipeline? (200 Drug Target Strategies and 409 Drugs)
  • 8 Compound Strategies at Work: Competitive Benchmarking of Protein Kinase Drugs in Oncology by Compound Type (7 Compound Strategies)
  • 9 Selecting Cancer Indications for Protein Kinase Therapeutics (57 Different Cancer Indications)
  • 10 Portfolio Planning: Competitive Benchmarking of Protein Kinase Cancer Therapeutic Pipeline by Investigator (160 Investigators)
  • 12 Drug Index
  • 13 Company Index
  • Figures: Includes 6 Figures
  • Tables: Includes 302 Tables
  • Total Number of Pages: 1442

Featured Companies

This Report Includes the Following Companies:

  • 4SC
  • Abbott
  • Abiogen
  • Abraxis BioScience
  • AC Immune
  • Access
  • Adaptimmune
  • Aduro BioTech
  • Advanced Life Sciences
  • Advaxis
  • Advenchen
  • AEgera
  • AEterna Zentaris
  • Aida Pharmaceuticals
  • Aileron Therapeutics
  • Akela Pharma
  • Alethia Biotherapeutics
  • Alfacell
  • Alnylam
  • AlphaVax
  • Ambit Biosciences
  • Ambrilia Biopharma
  • Amgen
  • Amphora
  • Anadys Pharmaceuticals
  • Anaphore
  • Anavex Life Sciences
  • Antisoma
  • Aphios
  • Apogenix
  • ApopLogic Pharmaceuticals
  • Apthera
  • Ariad
  • Arno Therapeutics
  • ArQule
  • Array BioPharma
  • Ascenta Therapeutics
  • Astellas
  • Astex Therapeutics
  • AstraZeneca
  • Attenuon
  • AVI BioPharma
  • Avila Therapeutics
  • Basilea Pharmaceutica
  • Bavarian Nordic
  • Bayer
  • Bellicum Pharmaceuticals
  • Benitec
  • Berkeley Lab
  • BioAlliance Pharma
  • BioAxone
  • Biocad
  • Biogen Idec
  • BioInvent
  • BioLineRx
  • Biomas
  • Bionovo
  • Biostar
  • Biotecnol
  • BioVex
  • Boehringer Ingelheim
  • Bristol-Myers Squibb
  • BTG
  • Cadila
  • Callisto Pharmaceuticals
  • CanBas
  • Cancer Research Technology
  • CDG Therapeutics
  • Celera
  • Celgene
  • Cell Genesys
  • Cell Therapeutics
  • Celldex Therapeutics
  • Cephalon
  • CG Therapeutics
  • ChemoCentryx
  • Chlorogen
  • Chroma Therapeutics
  • Cleveland BioLabs
  • CombinatoRx
  • CompleGen
  • Compugen
  • Coronado Biosciences
  • Cosmo Pharmaceuticals
  • Critical Outcome Technologies
  • CSL
  • Curis
  • Cyclacel
  • Cylene Pharmaceuticals
  • Cynvec
  • CytImmune Sciences
  • Cytochroma
  • CytRx
  • Daewoong
  • Daiichi Sankyo
  • Dainippon Sumitomo Pharma
  • Deciphera Pharmaceuticals
  • Dendreon
  • DeveloGen
  • Dyax
  • Eisai
  • Elara Pharmaceuticals
  • Eleos
  • Eli Lilly
  • Emergent BioSolutions
  • Enkam Pharmaceuticals
  • EntreMed
  • Epeius Biotechnologies
  • EpiCept
  • Erimos
  • Exelixis
  • Galapagos
  • Genentech
  • Generex
  • GenOdyssee Pharmaceuticals
  • Genta
  • GENTICEL
  • Gerolymatos
  • Geron
  • GlaxoSmithKline
  • Gliknik
  • GlobeImmune
  • GlycoGenesys
  • Glycotope
  • GPC Biotech
  • Gradalis
  • Green Cross
  • Hanmi
  • Harbor BioSciences
  • Hoffmann-La Roche
  • Human Genome Sciences
  • Ichor Medical Systems
  • Idera Pharmaceuticals
  • ImClone Systems
  • ImmunoCellular Therapeutics
  • ImmunoFrontier
  • Immunotope
  • Incyte Corporation
  • Infinity Pharmaceuticals
  • Innate Pharma
  • InNexus Biotechnology
  • Inovio
  • Insmed
  • Insys Therapeutics
  • Intradigm
  • Introgen Therapeutics
  • ISA Pharmaceuticals
  • Isis Pharmaceuticals
  • ISU ABXIS
  • Johnson & Johnson
  • KAI Pharmaceuticals
  • Kalypsys
  • Keryx Biopharmaceuticals
  • Kiadis
  • Kirin Pharma
  • Kyowa Hakko Kirin
  • Leo
  • Ligand
  • Locus Pharmaceuticals
  • Lorus Therapeutics
  • MaxoCore Pharmaceuticals
  • Medical Marketing International
  • MediGene
  • Medisyn Technologies
  • Menarini
  • Merck & Co
  • Merck KGaA
  • MethylGene
  • Micromet
  • Mitsubishi Tanabe Pharma
  • MolMed
  • Mologen
  • Nemod Biotherapeutics
  • NeoPharm
  • Neovacs
  • Nereus Pharmaceuticals
  • Nerviano Medical Sciences
  • NicOx
  • Nidus Laboratories
  • NIH
  • Nippon Shinyaku
  • Non-industrial source
  • Northwest Biotherapeutics
  • Novacea
  • NovaLead
  • Novartis
  • NovaRx
  • Novelix
  • Novogen
  • Oncalis
  • OncoMune
  • Onconova
  • OncoTherapy Science
  • Oncothyreon
  • Oncovir
  • Onyvax
  • OSI Pharmaceuticals
  • Oxford BioMedica
  • OXiGENE
  • PanaGin
  • Patrys
  • Pepscan Systems
  • Pepscan Therapeutics
  • Peregrine Pharmaceuticals
  • Pfizer
  • Pharmacyclics
  • PharmaGap
  • PharmaMar
  • Pharmexa
  • Pharminox
  • Pierre Fabre
  • Piramal
  • Plexxikon
  • Prima Biomed
  • Progenics Pharmaceuticals
  • ProMetic Life Sciences
  • Protherics
  • QLT
  • Radient Pharmaceuticals
  • Reata Pharmaceuticals
  • Receptor BioLogix
  • Regulon
  • responsif
  • Rexahn
  • Rigel
  • Rosetta Genomics
  • Sanofi
  • Sanofi-Aventis
  • Santaris Pharma
  • Sareum
  • SBI Biotech
  • SBIO
  • Scancell
  • Schering-Plough
  • SciClone Pharmaceuticals
  • Seattle Genetics
  • Semafore Pharmaceuticals
  • Senesco Technologies
  • Sigma-Tau
  • Silence Therapeutics
  • SRI International
  • SuperGen
  • Supratek Pharma
  • Switch Pharma
  • SymBio Pharmaceuticals
  • Symbiotec
  • Takeda
  • TapImmune
  • Targa Therapeutics
  • TargeGen
  • Taxolog
  • Tekmira Pharmaceuticals
  • Telik
  • TetraLogic Pharmaceuticals
  • Teva
  • Thallion Pharmaceuticals
  • Therion Biologics
  • Theryte
  • Tigris Pharmaceuticals
  • ToolGen
  • TopoTarget
  • Tracon Pharmaceuticals
  • Transgene
  • UCB
  • UMN Pharma
  • United Biomedical
  • Vaccinex
  • ValiRx
  • VasGene Therapeutics
  • Vaxil BioTherapeutics
  • Vaxon Biotech
  • VaxOnco
  • VBL Therapeutics
  • Vectura
  • Velacor Therapeutics
  • Vertex Pharmaceuticals
  • Vical
  • VioQuest
  • Viragen
  • Viralytics
  • Virionics
  • ViroMed
  • ViroTarg
  • VM Discovery
  • Wyeth
  • Xencor
  • Zensun

Featured Drugs

A Shortlist of Drugs Included are:

  • 131I-tositumomab
  • ADXS11-001
  • AE-37
  • AEG-35156
  • ALVAC-CEA/B7.1
  • alvocidib
  • AME-133
  • APG-101
  • ARQ-197
  • AS-101
  • AS-1411
  • astuprotimut-r
  • AVX-701
  • axitinib
  • bardoxolone methyl
  • belagenpumatucel-L
  • belinostat
  • BIBW-2992
  • bortezomib
  • bosutinib
  • BP-GMAX-CD1
  • brivanib alaninate
  • BZL-101
  • Cadi-05
  • canfosfamide hydrochloride
  • CB-10-01
  • CEA-TRICOM
  • cediranib
  • cenersen
  • CG-201
  • cintredekin besudotox
  • CMLVAX-100
  • conatumumab
  • crolibulin
  • CTL901
  • CTP-37
  • CVac
  • dasatinib
  • DCVax-prostate
  • deforolimus
  • dinaciclib
  • dulanermin
  • E-75
  • enzastaurin hydrochloride
  • erlotinib
  • everolimus
  • fosbretabulin tromethamine
  • fowlpox-PSA vaccine
  • gataparsen
  • gefitinib
  • GRNVAC1
  • GT-111
  • GV-1001
  • GV-1002
  • GVAX
  • GVX-3322
  • HE-3235
  • Her-2/Neu peptides
  • ibritumomab tiuxetan
  • idronoxil
  • IGN-101
  • imatinib mesilate
  • imetelstat
  • ImmunoVEX tri-melan
  • IMO-2055
  • INGN-225
  • kahalalide F
  • lapatinib ditosylate
  • lestaurtinib
  • litronesib
  • lonaprisan
  • lumiliximab
  • MAGE-3-TK
  • mapatumumab
  • ME-103
  • MGN-1601
  • midostaurin
  • MKC-1
  • mocetinostat
  • motesanib diphosphate
  • motexafin gadolinium
  • MSI vaccine
  • MVA-BN
  • MVA-BN Her-2 vaccine
  • navitoclax
  • nilotinib
  • Norelin
  • noscapine
  • obinutuzumab
  • oblimersen sodium
  • ON-01910
  • Oncohist
  • Onyvax-105
  • OTS-102
  • panobinostat
  • PANVAC-VF
  • PAT-SC1
  • pazopanib hydrochloride
  • PBI-1402
  • PCI-24781
  • pDOM-PSMA27
  • PEP-223
  • plitidepsin
  • poly-ICLC
  • PR1:169-177 peptide
  • PROSTVAC
  • PX-104.1
  • PX-12
  • quarfloxacin
  • quinacrine
  • R-(-)-gossypol
  • RAF-265
  • ramucirumab
  • retaspimycin
  • Reximmune-C
  • rindopepimut
  • sagopilone
  • SAI-EGF
  • seliciclib
  • sorafenib tosylate
  • SPC-2996
  • s-lapachone
  • Stimuvax
  • SU-6668
  • sunitinib malate
  • tanespimycin
  • temsirolimus
  • terameprocol
  • TG-4001
  • TG-4010
  • thymalfasin
  • tigapotide triflutate
  • tigatuzumab
  • tipifarnib
  • TL-32711
  • triciribine phosphate
  • TroVax
  • TRU-016
  • vandetanib
  • verpasep caltespen
  • volasertib
  • vosaroxin
  • VX-001
  • XL-147
  • XL-184
  • XL-647
  • ZYC-300
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