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市場調查報告書

血管新生,Protein Kinase抗化劑,胜肽:藥物開發策略分析

Triple Analysis: Angiogenesis, Protein Kinase Inhibitors and Peptides

出版商 BioSeeker Group AB
出版日期 2012年05月 商品編碼 224512
內容資訊 英文 5550 Pages
價格
US $ 5175 PDF


血管新生,Protein Kinase抗化劑,胜肽:藥物開發策略分析 是由出版商BioSeeker Group AB在2012年05月所出版的。 這份英文市場調查報告書包含5550 Pages 價格從美金5175起跳。

簡介

本報告以癌症治療藥開發策略上血管新生及Protein Kinase抗化劑的機制、目標、影響領域及胜肽的化合物領域為焦點,彙整各種的藥劑目標策略,化合物策略競爭基準,開發平台及最佳投資組合計劃等彙整資料,為您概述為以下內容。

第1章 血管新生

  • 本報告的範圍
  • 為達成最高治療效果及投資報酬率的治療目標檢討
  • 新藥的上市:影響血管新生的癌治療藥目標策略
  • 使用中的化合物策略:影響血管新生各化合物策略的治療樂物競爭基準
  • 影響藥品作用的血管新生的癌症症狀
  • 開發平台和最佳投資組合計劃:影響癌症治療藥開發平台血管新生的競爭基準
  • 免責聲明
  • 藥品目錄
  • 企業目錄

第2章 Protein Kinase抗化劑

  • 本報告的範圍
  • 為達成最高治療效果及投資報酬率的治療目標檢討
  • 新藥的上市:癌症的Protein Kinase抗化劑治療開發平台上指定的藥劑目標是否成熟,是否有特色,臨床評估如何
  • 使用中的化合物策略:各化合物策略競爭基準
  • Protein Kinase抗化劑癌症症狀
  • 最佳投資組合計劃:Protein Kinase抗化劑癌症治療藥開發平台的競爭基準
  • 藥品目錄
  • 企業目錄
  • 圖表

第3章 胜肽

  • 本報告的範圍
  • 胜肽治療藥物的優點與缺點
  • 為達成最高治療效果及投資報酬率的治療目標檢討
  • 新藥的上市:各開發階段的胜肽藥劑目標策略
  • 為了開發藥劑的癌症病狀的選擇
  • 開發平台及最佳投資組合:腫瘤學上的胜肽開發平台的競爭基準
  • 免責聲明
  • 藥品目錄
  • 企業目錄
  • 圖表

目錄

Abstract

This triple analysis focuses on cancer drug development strategies by the two mechanism/target/effect areas of Angiogenesis and Protein Kinase Inhibitors and by the compound strategy of Peptides. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.

Below is a short synopsis of each part included in this report:

Part I: Angiogenesis

The angiogenesis report part comprises defined and up to date development strategies for 239 drugs affecting angiogenesis in oncology within the portfolio of 148 investigators, from Preclinical to Marketed. This report part extensively analyses 174 identified targets of angiogenesis affecting drugs, organized into 167 drug target strategies, and assesses them in 64 different cancer indications.

Part II: Protein Kinase Inhibitors

The protein kinase report comprises defined and up to date development strategies for 409 protein kinase drugs (990 projects) within the portfolio of 160 investigators, from Ceased to Marketed. This report part extensively analyses 133 identified targets of protein kinase drugs, organized into 200 drug target strategies, and assesses them in 57 different cancer indications.

Part III: Peptides

The cancer peptide drug report part comprises defined and up to date development strategies for 152 peptide drugs in oncology within the portfolio of 104 companies world-wide, from Ceased to Marketed. The report extensively analyses their 123 identified drug targets, organized into 103 drug target strategies, and assesses them in 56 cancer indications.

The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies' pipeline and portfolio planning (PPP) in cancer by:

  • Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
  • Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug's properties
  • Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
  • Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
  • Supporting development of integrative molecule, pathway and disease area strategies
  • Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment

This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.

Table of Contents

Key Topics Covered:

Part I: Angiogenesis

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (174 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Cancer Drugs Affecting Angiogenesis by their Highest Stage of Development (167 Drug Target Strategies and 239 Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Cancer Drugs Affecting Angiogenesis by Compound Strategy (7 Different Compound Strategies)
  • 9. Selecting Cancer Indications for Angiogenesis Affecting Drugs in Oncology (64 Cancer Indications)
  • 10. Pipeline and Portfolio Planning: Competitive Benchmarking of the Angiogenesis Affecting Drug Pipeline in Oncology by Investigator (148 Investigators)
  • 10. Disclaimer
  • 11. Drug Index
  • 12. Company Index
  • Figures: Includes 7 Figures
  • Tables: Includes 300 Tables
  • Total Number of Pages: 1227

Part II: Protein Kinase Inhibitors

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (133 Drug Targets)
  • 7. The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Profiles Identified in the Cancer Protein Kinase Therapeutic Pipeline? (200 Drug Target Strategies and 409 Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Protein Kinase Drugs in Oncology by Compound Type (7 Compound Strategies)
  • 9. Selecting Cancer Indications for Protein Kinase Therapeutics (57 Different Cancer Indications)
  • 10. Portfolio Planning: Competitive Benchmarking of Protein Kinase Cancer Therapeutic Pipeline by Investigator (160 Investigators)
  • 12. Drug Index
  • 13. Company Index
  • Figures: Includes 6 Figures
  • Tables: Includes 302 Tables
  • Total Number of Pages: 1442

Part III: Peptides

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Peptide Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (123 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Peptide Drugs in Oncology by their Highest Stage of Development (103 Drug Targets Strategies and 152 Peptide Drugs)
  • 8. Selecting Indication for Peptide Drugs in Oncology (56 Cancer Indications)
  • 9. Pipeline and Portfolio Planning: Competitive Benchmarking of the Peptide Drug Pipeline in Oncology by Investigator (104 Investigators and 152 Peptide Drugs)
  • 10. Disclaimer
  • 11. Drug Index
  • 12. Company Index
  • Figures: Includes 5 Figures
  • Tables: Includes 207 Tables
  • Total Number of Pages: 906

This Report Includes the Following Companies:

  • 4SC
  • 7TM Pharma
  • Abbott
  • Abiogen
  • Abraxis BioScience
  • Acceleron Pharma
  • Access
  • ACT Biotech
  • Active Biotech
  • Adherex
  • Advanced Cancer Therapeutics
  • Advantagene
  • Advaxis
  • Advenchen
  • Aegera
  • Aeterna Zentaris
  • Affymax
  • Agennix
  • Aida Pharmaceuticals
  • Aileron Therapeutics
  • Alethia Biotherapeutics
  • Alfacell
  • Allostera
  • Allosterix
  • Alnylam
  • AlphaVax
  • Ambit Biosciences
  • Ambrilia Biopharma
  • Amgen
  • Amphora
  • Anchor Therapeutics
  • AngioChem
  • Angiogen
  • Angiogenex
  • Angstrom Pharmaceuticals
  • Ansaris
  • Antisoma
  • AplaGen Biopharmaceuticals
  • ApopLogic Pharmaceuticals
  • Apthera
  • Arana Therapeutics
  • Ardana
  • Ariad
  • Arno Therapeutics
  • ArQule
  • Array BioPharma
  • Astellas
  • Astex Therapeutics
  • AstraZeneca
  • Attenuon
  • Austrianova
  • AVI BioPharma
  • Baxter International
  • Bayer
  • Benitec
  • Berkeley Lab
  • BioAlliance Pharma
  • BioAxone
  • Biocompatibles
  • Biokine Therapeutics
  • Biotecnol
  • Boehringer Ingelheim
  • Bolder BioTechnology
  • Bristol-Myers Squibb
  • BTG
  • Callisto Pharmaceuticals
  • CanBas
  • Cancer Advances
  • Cancer Innovations
  • Cancer Research Technology
  • CDG Therapeutics
  • Celecure
  • Celgene
  • Cell Therapeutics
  • CellCeutix
  • Celldex Therapeutics
  • Cellmid
  • Cephalon
  • ChemoCentryx
  • Chemokine Therapeutics
  • China Sky One Medical
  • Choongwae
  • Circadian Technologies
  • Cleveland BioLabs
  • Clinuvel
  • CompleGen
  • Compugen
  • Cue Biotech
  • Curaxis
  • Curis
  • Cyclacel
  • Cylene Pharmaceuticals
  • Cytochroma
  • Daiichi Sankyo
  • Dainippon Sumitomo Pharma
  • Deciphera Pharmaceuticals
  • Dendreon
  • DeveloGen
  • Diatos
  • Digna Biotech
  • Dongkook Pharm
  • Dyax
  • Eisai
  • Elara Pharmaceuticals
  • Eli Lilly
  • Endo Pharmaceuticals
  • Endocyte
  • Enkam Pharmaceuticals
  • EntreMed
  • Esperance Pharmaceuticals
  • Exelixis
  • ExonHit Therapeutics
  • Facet Biotech
  • Five Prime Therapeutics
  • Galapagos
  • Galena Biopharma
  • GammaCan
  • Genentech
  • Generex
  • Genmab
  • GENova Biotherapeutics
  • Genovax
  • GlaxoSmithKline
  • Gliknik
  • GlycoGenesys
  • GP Pharm
  • Green Cross
  • Gryphon Therapeutics
  • Hanmi
  • Hoffmann-La Roche
  • Hy BioPharma
  • Idera Pharmaceuticals
  • ImClone Systems
  • ImmunoCellular Therapeutics
  • ImmunoFrontier
  • ImmunoGen
  • Immunotope
  • ImmuPharma
  • Incyte Corporation
  • Innovive
  • Inovio
  • Insmed
  • Introgen Therapeutics
  • ISA Pharmaceuticals
  • Isis Pharmaceuticals
  • ISU ABXIS
  • Johnson & Johnson
  • KAI Pharmaceuticals
  • Kalypsys
  • Karus Therapeutics
  • Karyon-CTT
  • Kiadis
  • Kirin Pharma
  • Kringle Pharma
  • Kyowa Hakko Kirin
  • Lee's Pharmaceutical
  • Locus Pharmaceuticals
  • Lorus Therapeutics
  • Marillion Pharmaceuticals
  • MAT Biopharma
  • MaxoCore Pharmaceuticals
  • Mbiotec
  • Meda
  • MediGene
  • Mediolanum
  • Medisyn Technologies
  • Merck & Co
  • Merck KGaA
  • Mersana Therapeutics
  • MethylGene
  • Micromet
  • Mitsubishi Tanabe Pharma
  • MolMed
  • Morvus Technology
  • Nektar Therapeutics
  • Nemod Biotherapeutics
  • NeoPharm
  • Nerviano Medical Sciences
  • Neurobiological Technologies
  • NewSouth Innovations
  • NicOx
  • Nidus Laboratories
  • NIH
  • Nippon Shinyaku
  • Non-industrial source
  • Novartis
  • Novelix
  • Novogen
  • NPS Pharmaceuticals
  • Oasmia
  • Oncalis
  • Onconova
  • OncoTherapy Science
  • Oncothyreon
  • OSI Pharmaceuticals
  • Oxford BioMedica
  • OXiGENE
  • Pepscan Therapeutics
  • Peptagen
  • PepTx
  • Peregrine Pharmaceuticals
  • Pfizer
  • Pharmacopeia
  • Pharmacyclics
  • PharmaGap
  • PharmaMar
  • Pharmexa
  • Pharminox
  • Philogen
  • PhiloGene
  • Pierre Fabre
  • Piramal
  • Plexxikon
  • Progen
  • Protagonist
  • Protein Sciences
  • PTC Therapeutics
  • Q Chip
  • QLT
  • Raptor Pharmaceutical
  • Reata Pharmaceuticals
  • Receptor BioLogix
  • Regeneron
  • Rexahn
  • Rigel
  • Sanofi-Aventis
  • Santaris Pharma
  • Sareum
  • SBIO
  • Scancell
  • Schering-Plough
  • SciClone Pharmaceuticals
  • Semafore Pharmaceuticals
  • Serometrix
  • Shire
  • Silence Therapeutics
  • Simcere Pharmaceuticals
  • Soligenix
  • Spear Therapeutics
  • Spectrum Pharmaceuticals
  • SRI International
  • SuperGen
  • Supratek Pharma
  • Switch Pharma
  • SynDevRx
  • Takeda
  • Targa Therapeutics
  • TargeGen
  • Tau Therapeutics
  • Tekmira Pharmaceuticals
  • Telik
  • Thallion Pharmaceuticals
  • Therion Biologics
  • Theryte
  • ThromboGenics
  • Tigris Pharmaceuticals
  • ToolGen
  • TopoTarget
  • Tracon Pharmaceuticals
  • UCB
  • Unigene
  • United Biomedical
  • VasGene Therapeutics
  • Vaxil BioTherapeutics
  • Vaxon Biotech
  • VaxOnco
  • VBL Therapeutics
  • Vertex Pharmaceuticals
  • Wilex
  • ViroMed
  • Wyeth
  • Xencor
  • Xerion
  • Xigen
  • Zelos Therapeutics
  • Zensun

A Shortlist of Drugs Included are:

  • A6
  • abarelix
  • ABT-510
  • AEZS-108
  • afamelanotide
  • aflibercept
  • alvocidib
  • angiopep+paclitaxel
  • apatinib
  • ARQ-197
  • axitinib
  • bevacizumab
  • BIBF-1120
  • BIBW-2992
  • brivanib alaninate
  • CBP-501
  • cediranib
  • cilengitide
  • corticorelin acetate
  • dasatinib
  • deforolimus
  • deslorelin
  • E-75
  • emepepimut-S
  • endostatin
  • enzastaurin hydrochloride
  • erlotinib
  • everolimus
  • fosbretabulin tromethamine
  • gefitinib
  • goserelin
  • GV-1001
  • GX-301
  • HBP-347
  • histrelin
  • idronoxil
  • imatinib mesilate
  • imMucin
  • INGN-241
  • IPP-204106
  • ISA-P53-01
  • lapatinib ditosylate
  • lestaurtinib
  • leuprolide
  • leuprolide acetate
  • linifanib
  • MDX-1379
  • midostaurin
  • motesanib diphosphate
  • NAFB001
  • netupitant
  • nilotinib
  • OTS-102
  • ozarelix
  • pasireotide
  • pasireotide LAR
  • patupilone
  • pazopanib hydrochloride
  • ramucirumab
  • ridaforolimus
  • rindopepimut
  • romurtide
  • sorafenib tosylate
  • sotatercept
  • sunitinib malate
  • talactoferrin alfa
  • tanespimycin
  • temsirolimus
  • thymalfasin
  • tigapotide triflutate
  • tipifarnib
  • TM-30339
  • vandetanib
  • VX-001
  • XL-184
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