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市場調查報告書
SNP 基因定型產品／服務市場
The Market for SNP Genotyping Products & Services
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本報告已在2011年07月19日停止出版。
Abstract
A single nucleotide polymorphism (SNP), a single base pair variation, is the most commonly occurring variation in DNA. SNPs provide a powerful approach to understanding the connection between genetic variation and its physical manifestation, and as such, are a main focus of the pharmacogenomics arena. Based on a 34-question survey of more than 500 scientists who currently perform SNP genotyping, The Market for SNP Genotyping Products & Services details researchers experimental parameters, current and future levels of sample throughput and the genotyping methods utilized in order to benchmark the current state of the market. It reveals respondents satisfaction with their genotyping method and determines the attributes of those methods that are of the greatest importance, as well as areas where the methods perform above or below expectations. Additionally, this report examines the practice of outsourcing samples to SNP genotyping providers by disclosing respondents reasons for
outsourcing, factors that contributed to the selection of a particular genotyping service provider and their satisfaction with that provider.
By using this report to understand the actual experiences, needs and preferences of researchers, suppliers of SNP genotyping products and services will be better positioned to refine existing tools to appeal to the diverse needs of their target market and to extend the use of their products and services into additional laboratories.
The major objectives of this report are as follows:
- Identify the preferred techniques used to perform SNP genotyping.
- Understand the extent of outsourcing of SNP genotyping and why researchers decide to outsource.
- Determine current levels of throughput and multiplexing as well as reaction costs for SNP genotyping.
- Identify the preferred suppliers of SNP genotyping products and services.
- Measure respondents levels of satisfaction with SNP genotyping service providers and SNP genotyping products and services.
- Explore unmet needs, as well as the future utilization of SNP genotyping.
Table of Contents
Section 1. Analysis and Interpretation of Survey Results
- Executive Summary
- Introduction
- Key Findings
- Study Objectives
- Experimental Parameters
- Objectives of SNP genotyping work
- Species/systems studied
- Experimental design
- Where SNP genotyping is performed
- Throughput
- Multiplexing and throughput
- SNP genotyping products
- Instrumentation
- Software solutions
- In-house Genotyping
- Experimental set-up
- Methods of genotyping
- Genotyping method performance attributes
- Market Dynamics: Outsourcing SNP Genotyping
- Reasons for outsourcing
- Preferred suppliers
- Product performance attributes
- Future Directions in SNP Genotyping
- Accommodating increased throughput
- Desired future improvements
- Genotyping and clinical practice
- Conclusion
Section 2. Study Methodology and Demographics
- Methodology
- Definition of Terms
- Demographics
- Questionnaire
Section 3. Presentation of Survey DataUsage and Applications
- Types of genetic variance studied
- Primary objectives of SNP genotyping work
- Specific species/specimens studied using SNP genotyping work
- Phases of SNP genotyping that are elements of a typical SNP genotyping study conducted by labs
- Percentage of SNP genotyping performed at specific locations
- In-House Genotyping
- Database resources used to select validated SNPs for further study
- Modified oligonucleotides used when performing SNP genotyping
- Detection methods used when performing SNP genotyping
- Automated workflow solutions currently incorporated into SNP genotyping workflow
- Use of PCR as a component of SNP genotyping methods performed
- Methods used to perform SNP genotyping
- Methods primarily used to perform SNP genotyping
- Overall satisfaction with specific features of SNP genotyping methods
- Satisfaction with primary method for SNP genotyping
- Products used for SNP genotyping
- Instrumentation used for SNP genotyping
- Software solutions used for SNP genotyping, allele- or base-calling analysis
- Outsourcing SNP Genotyping
- Primary reason for outsourcing SNP genotyping
- Contributing factors for outsourcing to particular service providers
- Service providers used to conduct SNP genotyping studies
- Satisfaction with specific features of the SNP genotyping performed by specific service providers
- Overall satisfaction with SNP genotyping performed by service providers
- Experimental Design and Throughput
- Scope of a typical SNP genotyping study conducted in a lab
- Length of time a typical SNP genotyping study takes to be completed
- Number of SNPs scored in each typical reaction
- Average level of SNP genotyping throughput
- Expectation for level of SNP genotyping throughput to change over the next 12 months
- Primary plan to accommodate change in level of throughput
- Average cost to analyze a single SNP
- Future Developments
- Most valuable improvement to SNP genotyping
- Perceived greatest challenges to the integration of genotyping/pharmacogenomics into clinical practice
Section 4. Appendices
- Insights and Perspectives
- Cross-Tabulations of Survey Data
- Other Recent Publications
- About BioInformatics
- Our Valued clients
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