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市場調查報告書

胞外體診斷、治療:全球市場

Exosome Diagnostics and Therapeutics: Global Markets

出版商 BCC Research 商品編碼 354591
出版日期 內容資訊 英文 159 Pages
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胞外體診斷、治療:全球市場 Exosome Diagnostics and Therapeutics: Global Markets
出版日期: 2016年03月16日 內容資訊: 英文 159 Pages
簡介

全球胞外體診斷、治療市場,預計2016年達1,610萬美金,此後以47.3%的年複合成長率成長,2021年達到1億1,180萬美元。

本報告提供全球胞外體診斷、治療市場相關調查,全球市場及相關技術概要,世界市場趨勢分析,新、傳統的診斷方法分析,目前治療、預測不久將來會實現的治療分析,市場動態分析,及主要企業的簡介等彙整。

第1章 簡介

第2章 摘要

第3章 胞外體市場簡介

  • 概要
    • 胞外體定義、用語體系
    • 胞外體的發現
    • 胞外體的生成、處理
    • 胞外體的組成
    • 胞外體的分離與檢測
    • 胞外體研究、產品開發的生物資訊學資料庫
    • 胞外體的功能、生理功能

第4章 胞外體診斷市場

  • 概要
    • 診斷生物標記的外體蛋白品質
    • 診斷生物標記的外體核酸
    • 對胞外體診斷產品開發來說的市場可能性的癌症診斷
    • 對胞外體診斷產品開發來說的市場可能性的CNS疾病、神經退化性疾病
    • 對胞外體診斷產品開發來說的市場可能性的感染疾病
    • 對胞外體診斷產品開發來說的市場可能性的心血管疾病
    • 對胞外體診斷產品開發來說的市場可能性的產前檢查
    • 胞外體型診斷部門的市場參與企業
    • EXOSOME DIAGNOSTICS
    • EXOSOME SCIENCES/AETHLON MEDICAL
    • CARIS LIFE SCIENCES
    • NANOSOMIX
    • AMARANTUS BIOSCIENCE
    • YMIR GENOMICS
    • SISTEMIC
    • EXOSOMICS SIENA SPA
    • ORION PHARMA
    • NX PHARMAGEN
  • 胞外體市場上目前診斷部門的評估

第5章 胞外體治療市場

  • 概要
    • 內因性治療活性
    • 免疫學的適合性
    • 胞外體媒介治療的世代
    • 胞外體型診斷部門的市場參與企業
    • PANACEA PHARMACEUTICAL
    • REDERMIS
    • CODIAK BIOSCIENCES
    • EXOVITA BIOSCIENCES
    • BIOREGENERATIVE SCIENCES
    • AEGLE THERAPEUTICS
    • CAPRICOR
    • EXOCYTE THERAPEUTICS
    • RENEURON
    • MEDISTEM/INTREXON CORP
    • THERAPEUTICS SOLUTIONS INTERNATIONAL
    • DREIROSEN PHARMA
    • PARADIGM BIOPHARMACEUTICALS
    • 有胞外體研究計劃的可能性的其他的醫藥品、生物科技企業
    • 胞外體市場開發的指標的臨床實驗
    • 胞外體市場上目前診斷部門的評估

第6章 胞外體試劑、研究工具市場

  • 概要
    • 胞外體研究的分離方法、試劑
  • 市場參與企業
    • SYSTEM BIOSCIENCES (SBI)
    • HANSABIOMED
    • 101BIO
    • EVOMIC SCIENCE
    • AMSBIO
    • CELL GUIDANCE SYSTEMS
    • CILOA
    • EXCYTEX
    • NANOSIGHT
    • IZON SCIENCE
  • 胞外體市場上目前工具、試劑的評估

第7章 胞外體市場專利分析

  • 概要

第8章 特定的生物醫藥品市場相關胞外體研究的影響

  • 概要
    • 胞外體研究帶給生物標記、診斷產業的影響
    • 胞外體研究帶給微型核糖核酸市場的影響
    • 胞外體研究帶給液態切片市場的影響
    • 胞外體研究帶給幹細胞技術市場的影響
    • 胞外體研究帶給產前診斷市場的影響

第9章 市場摘要

第10章 主要企業概要

  • AETHLON MEDICAL INC.
  • EXOSOME DIAGNOSTICS INC.
  • NANOSOMIX INC.
  • SYSTEM BIOSCIENCES (SBI)
  • THERMO FISHER SCIENTIFIC INC.
  • YMIR GENOMICS LLC

第11章 本調查提及的企業清單

  • 101BIO
  • AEGLE THERAPEUTICS
  • AETHLON MEDICAL INC.
  • AMARANTUS BIOSCIENCE HOLDINGS INC.
  • AMSBIO LLC
  • BIOREGENERATIVE SCIENCES INC.
  • CAPRICOR THERAPEUTICS
  • CARIS LIFE SCIENCES
  • CELL GUIDANCE SYSTEMS LLC
  • CILOA
  • CODIAK BIOSCIENCES
  • DREIROSEN PHARMA
  • EVOMIC SCIENCE LLC
  • EXCYTEX
  • EXIQON, INC
  • EXOCYTE THERAPEUTICS PTE LTD.
  • EXOSOME DIAGNOSTICS INC.
  • EXOSOME SCIENCE
  • EXOSOMICS SIENA SPA
  • EXOVITA BIOSCIENCES
  • HANSABIOMED
  • ITH, IMMUNE THERAPY HOLDINGS AB
  • IZON SCIENCE
  • JSR MICRO INC.
  • MEDISTEM/INTREXON CORP.
  • MILTENYI BIOTEC GMBH
  • NANOSIGHT/MALVERN INSTRUMENTS LTD.
  • NANOSOMIX INC.
  • NEW ENGLAND PEPTIDE INC.
  • NORGEN BIOTEK CORP
  • NX PHARMAGEN
  • ORION PHARMA LTD.
  • PANACEA PHARMACEUTICALS
  • PARADIGM BIOPHARMACEUTICALS
  • PARTICLE METRIX INC.
  • PFIZER
  • PROMEGA CORP.
  • QIAGEN
  • REDERMIS
  • RENEURON GROUP PLC
  • SISTEMIC
  • SYSTEM BIOSCIENCES (SBI)
  • THERAPEUTICS SOLUTIONS INTERNATIONAL
  • THERMOFISHER SCIENTIFIC
  • YMIR GENOMICS LLC

圖表

目錄
Product Code: BIO149A

REPORT HIGHLIGHTS

The global market for exosome diagnostics and therapeutics is projected to grow from $16.1 million in 2016 to $111.8 million in 2021, a five-year compound annual growth rate (CAGR) of 47.3%.

This report provides:

  • An overview of the global markets and related technologies for exosome diagnostics and therapeutics.
  • Analyses of global market trends, with data from 2015, estimates for 2016, and projections of CAGRs through 2021.
  • Breakdowns of new and exisiting diagnostic methods.
  • Evaluation of current therapeutics and those likely to be realized in the near future.
  • Analyses of the market's dynamics, specifically growth drivers, restraints, and opportunities.
  • Profiles of major players in the industry.

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REPORT SCOPE

SCOPE AND FORMAT

This report represents a current and important business tool to evaluate new commercial opportunities in the exosome diagnostics, therapeutics and research tools market. The geographic scope of this study covers the United States and companies worldwide. This market is complex and consists of a number of different sectors, each affected differently by scientific and technological development. The report identifies the main positive and negative factors in each sector and forecasts further trends and product and assay development in every category of this industry.

ANALYST'S CREDENTIALS

Dr. Marianna Tcherpakov has more than 10 years of experience as a bench scientist specializing in the area of biochemistry, cell biology and industrial assay development. She has contributed to a number of scientific publications and holds several patents. She has expertise as an assay development scientist and is familiar with different research field trends and likely future developments.

Table of Contents

CHAPTER 1 INTRODUCTION

  • STUDY GOALS AND OBJECTIVES
  • REASONS FOR DOING THIS STUDY
  • SCOPE AND FORMAT
  • METHODOLOGY AND INFORMATION SOURCES
  • INTENDED AUDIENCE
  • ANALYST'S CREDENTIALS
  • RELATED BCC RESEARCH REPORTS
  • BCC RESEARCH WEBSITE
  • DISCLAIMER

CHAPTER 2 SUMMARY

  • SUMMARY TABLE GLOBAL MARKET FOR EXOSOME INDUSTRY BY SECTOR, THROUGH 2021 ($ MILLIONS)
  • SUMMARY FIGURE GLOBAL MARKET FOR EXOSOME INDUSTRY BY SECTOR, 2014-2021 ($ MILLIONS)

CHAPTER 3 INTRODUCTION TO EXOSOME MARKET

  • OVERVIEW
    • EXOSOME DEFINITION AND NOMENCLATURE
    • TABLE 1 NOMENCLATURE OF EXOSOME PARTICLES
    • DISCOVERY OF EXOSOMES
    • TABLE 2 PUBLICATION TREND ON EXOSOME SUBJECT, 2003-2015 (NO. OF PUBLICATIONS)
    • FIGURE 1 PUBLICATION TREND ON EXOSOME SUBJECT, 2003-2015 (NO. OF PUBLICATIONS)
    • EXOSOME BIOGENENSIS AND PROCESSING
    • TABLE 3 STEPS IN EXOSOME BIOGENESIS AND PROCESSING
    • TABLE 4 PROTEINS ESSENTIAL IN EXOSOME BIOGENESIS AND PROCESSING
    • EXOSOME COMPONENTS
      • DNA in Exosomes
      • Proteins in Exosome
      • TABLE 5 PROTEINS FOUND IN EXOSOMES
      • RNA in Exosomes
      • TABLE 6 MICRORNA IN DIFFERENT BODILY FLUIDS
    • ISOLATION AND DETECTION OF EXOSOMES
      • Isolation Techniques
      • TABLE 7 METHODS FOR EXOSOME ISOLATION
      • Differential Centrifugation
        • FIGURE 2 DIFFERENTIAL CENTRIFUGATION PROCESS
        • Density Gradient Centrifugation
        • Size-Exclusion Chromatography
        • Filtration
        • FIGURE 3 CILIATED POROUS DEVICE DESIGNED TO ISOLATE EXOSOMES BY FILTRATION
        • Polymer-Based Precipitation
        • Immunological Separation
        • Isolation by Sieving
        • FIGURE 4 SIEVING MODELS FOR EXOSOME FILTRATION
        • TABLE 8 DISTRIBUTION OF EXOSOMES ISOLATION PROCEDURES IN THE STUDIES CATALOGED IN EXOCARTA (%)
      • Exosome Detection
    • BIOINFORMATICS DATABASES FOR EXOSOME RESEARCH AND PRODUCT DEVELOPMENT
      • ExoCarta
      • TABLE 9 STATISTICS OF DATA CATALOGED IN EXOCARTA, 2012
      • Vesiclepedia
      • TABLE 10 STATISTICS OF DATA CATALOGED IN VESICLEPEDIA, 2012
      • EVpedia
      • TABLE 11 STATISTICS OF DATA CATALOGED IN EVPEDIA, 2014
      • TABLE 12 COMPARISON OF DATABASES FOR EXOSOME STUDIES
    • EXOSOME FUNCTION AND PHYSIOLOGY

CHAPTER 4 EXOSOME DIAGNOSTICS MARKET

  • OVERVIEW
    • EXOSOMAL PROTEINS AS DIAGNOSTIC BIOMARKERS
    • TABLE 13 EXOSOMAL PROTEINS FOR CLINICAL DIAGNOSTIC APPLICATIONS
    • EXOSOMAL NUCLEIC ACIDS AS DIAGNOSTIC BIOMARKERS
    • TABLE 14 EXOSOMAL MICRORNA FOR CLINICAL DIAGNOSTIC APPLICATIONS
    • CANCER DIAGNOSTICS AS MARKET POTENTIAL FOR EXOSOME DIAGNOSTICS PRODUCT DEVELOPMENT
      • Prostate Cancer as Potential for Diagnostics Development in Exosome Sector
      • TABLE 15 STATISTICS FOR PROSTATE CANCER, 2015
      • TABLE 16 GLOBAL MARKET VALUE FOR PROSTATE CANCER DIAGNOSTICS AND RELATED COST ($ BILLIONS)
      • Breast Cancer as Potential for Diagnostics Development in Exosome Sector
      • TABLE 17 STATISTICS FOR BREAST CANCER, 2015
      • TABLE 18 GLOBAL MARKET VALUE FOR BREAST CANCER DIAGNOSTICS, THROUGH 2019 ($ BILLIONS)
      • Bladder Cancer as Potential for Diagnostics Development in Exosome Sector
      • TABLE 19 STATISTICS FOR BLADDER CANCER, 2015
      • TABLE 20 GLOBAL MARKET VALUE FOR BLADDER CANCER DIAGNOSTICS, 2015 ($ BILLIONS)
      • Ovarian Cancer as Potential for Diagnostics Development in Exosome Sector
      • TABLE 21 STATISTICS FOR OVARIAN CANCER, 2015
      • TABLE 22 GLOBAL MARKET VALUE FOR OVARIAN CANCER DIAGNOSTICS, 2015 ($ MILLIONS)
      • Lung Cancer as Potential for Diagnostics Development in Exosome Sector
      • TABLE 23 STATISTICS FOR LUNG CANCER, 2015
      • TABLE 24 GLOBAL MARKET VALUE FOR LUNG CANCER DIAGNOSTICS, 2015 ($ MILLIONS)
      • Liquid Biopsy as Potential for Diagnostics Development in Exosome Sector
      • TABLE 25 LIQUID VS. TISSUE BIOPSY
      • TABLE 26 GLOBAL MARKET VALUE FOR LIQUID BIOPSY MARKET, 2015 AND 2020 ($ BILLIONS)
    • CNS DISORDERS AND NEURODEGENRATION DISEASES AS MARKET POTENTIAL FOR EXOSOME DIAGNOSTICS PRODUCT DEVELOPMENT
    • TABLE 27 U.S. STATISTICS DATA FOR ALZHEIMER'S, 2015 (MILLIONS/$ BILLIONS)
    • TABLE 28 GLOBAL MARKET VALUE FOR ALZHEIMER'S DIAGNOSTICS, 2009 AND 2014 ($ BILLIONS)
    • INFECTIOUS DISEASES AS MARKET POTENTIAL FOR EXOSOME DIAGNOSTICS PRODUCT DEVELOPMENT
    • TABLE 29 GLOBAL STATISTICS DATA FOR HEPATITIS C INFECTION, 2015 (MILLIONS)
    • TABLE 30 GLOBAL MARKET VALUE FOR HEPATITIS C DIAGNOSTICS, 2015 ($ BILLIONS)
    • CARDIOVASCULAR DISEASES AS MARKET POTENTIAL FOR EXOSOME DIAGNOSTICS PRODUCT DEVELOPMENT
    • TABLE 31 U.S. STATISTICS DATA FOR CARDIOVASCULAR DISEASES, 2011
    • TABLE 32 GLOBAL MARKET VALUE FOR CARDIOVASCULAR DIAGNOSTICS, 2015 ($ BILLIONS)
    • PRENATAL TESTING AS MARKET POTENTIAL FOR EXOSOME DIAGNOSTICS PRODUCT DEVELOPMENT
    • TABLE 33 GLOBAL MARKET VALUE FOR PRENATAL DIAGNOSTICS, PREDICTIVE TESTS AND NEONATAL MONITORING, THROUGH 2019 ($ BILLIONS)
    • MARKET PARTICIPANTS IN EXOSOME-BASED DIAGNOSTICS SECTOR
    • EXOSOME DIAGNOSTICS
      • Research Tools/Kits
      • Diagnostics Market/Liquid Biopsy
      • TABLE 34 COMPARISON OF EXOSOME DIAGNOSTICS APPROACH TO OTHER LIQUID BIOPSY PLATFORMS
      • ExoDx Lung(ALK) and ExoDx Lung(EGFR T790M) for Lung Cancer Patients
      • ExoIntelliScore Prostate
      • Solid Tumor Mutation Panel
      • Partnerships
    • EXOSOME SCIENCES/AETHLON MEDICAL
    • CARIS LIFE SCIENCES
    • NANOSOMIX
    • AMARANTUS BIOSCIENCE
    • YMIR GENOMICS
    • SISTEMIC
    • EXOSOMICS SIENA SPA
    • ORION PHARMA
    • NX PHARMAGEN
  • EVALUATION OF CURRENT DIAGNOSTICS SECTOR IN EXOSOME MARKET
  • TABLE 35 GLOBAL MARKET SIZE FOR DIAGNOSTICS EXOSOME MARKET, THROUGH 2021 ($ MILLIONS)
  • FIGURE 5 GLOBAL MARKET SIZE FOR DIAGNOSTICS EXOSOME MARKET, 2014-2021 ($ MILLIONS)

CHAPTER 5 EXOSOME THERAPEUTICS MARKET

  • OVERVIEW
    • INTRINSIC THERAPEUTIC ACTIVITY
    • IMMUNOLOGICAL COMPATIBILITY
    • CARGO CAPABILITIES
    • GENERATION OF EXOSOME-MEDIATED THERAPEUTICS
      • Exosome Isolation and Purification from Biofluids or Cell Culture
      • Exosome-Producing Cells as a Source for Exosome Production
      • Engineering Exosomes as Therapeutic Delivery Vehicles
        • Protein Cargo
        • RNA Cargo
      • Targeting Exosomes to Specific Recipient Cells
      • Designing Exosome as Synthetic Vector
      • TABLE 36 EXAMPLES OF PHYSIOLOGICAL EFFECT OF EXOSOME DELIVERY
      • MARKET POTENTIAL FOR EXOSOME THERAPEUTICS
      • TABLE 37 TOP FIVE VACCINE PROVIDERS, 2014 ($ BILLIONS)
      • MARKET PARTICIPANTS IN EXOSOME-BASED THERAPEUTICS SECTOR
    • ATHELON MEDICAL
    • TABLE 38 MARKET FOR AETHLON MEDICAL, 2012-2015 ($ MILLIONS)
    • PANACEA PHARMACEUTICAL
    • REDERMIS
    • CODIAK BIOSCIENCES
    • EXOVITA BIOSCIENCES
    • BIOREGENERATIVE SCIENCES
    • AEGLE THERAPEUTICS
    • TABLE 39 U.S. STATISTICS FOR BURN INJURIES, 2015
    • TABLE 40 U.S. STATISTICS FOR PRESSURE ULCER
    • CAPRICOR
    • TABLE 41 REVENUE, COST AND PROFITS FOR CAPRICOR THERAPEUTICS, 2011-2014 ($ MILLIONS)
    • EXOCYTE THERAPEUTICS
    • RENEURON
    • MEDISTEM/INTREXON CORP
    • THERAPEUTICS SOLUTIONS INTERNATIONAL
    • DREIROSEN PHARMA
    • PARADIGM BIOPHARMACEUTICALS
    • ADDITIONAL PHARMA AND BIOTECH COMPANIES WITH POTENTIAL EXOSOME RESEARCH PROJECTS
    • CLINICAL TRIALS AS INDICATOR FOR EXOSOME MARKET DEVELOPMENT
    • TABLE 42 EXAMPLES OF CLINICAL TRIALS IN U.S. USING EXOSOME APPROACH
    • EVALUATION OF CURRENT THERAPEUTICS SECTOR IN EXOSOME MARKET
    • TABLE 43 GLOBAL MARKET SIZE OF THERAPEUTICS EXOSOME MARKET, THROUGH 2021 ($ MILLIONS)
    • FIGURE 6 GLOBAL MARKET SIZE OF THERAPEUTICS EXOSOME MARKET, 2014-2021 ($ MILLIONS)

CHAPTER 6 EXOSOME REAGENTS AND RESEARCH TOOLS MARKET

  • OVERVIEW
  • TABLE 44 MAIN STEPS IN EXOSOME RESEARCH APPROACH
    • ISOLATION METHODOLOGIES AND REAGENTS FOR EXOSOME RESEARCH
    • TABLE 45 EXAMPLES OF COMMERCIAL KITS AND REAGENTS FOR EXOSOME ISOLATION
    • TABLE 46 PERCENTAGE OF USE OF EACH ISOLATION TECHNIQUE FOR EXOSOME BY PURIFICATION
      • Detection Methodologies and Reagents for Exosome Research
        • Instruments for Exosome Detection
          • Nanosight NTA from Nanosight
          • qNano from Izon Science
          • ZetaView from Particle Metrix
        • Detection of Exosomes by Enzymatic Assay or ELISA Approach
        • TABLE 47 EXAMPLES OF DETECTION ASSAY
        • TABLE 48 EXAMPLES OF ANTIBODY PROVIDERS FOR EXOSOME RESEARCH
      • Characterization Methods and Reagents for Exosome Research
        • Protein Content Characterization
        • Nucleic Acid Content Characterization
        • TABLE 49 EXAMPLES OF RNA EXTRACTION COMMERCIAL KITS
        • TABLE 50 USAGE PERCENTAGE OF CHARACTERIZATION TECHNIQUES FOR EXOSOME SAMPLE
      • Engineering Methods and Reagents for Exosome Research
        • SBI Engineering Tools
        • Evomic Science Engineering Approach
        • Ciloa's Exosome Engineering Platform
        • Excytex and Its Synthetic Liposome/Exosome
      • Additional Products and Reagents for Exosome Research
      • TABLE 51 EXAMPLES OF PURIFIED EXOSOMES COMMERCIAL PRODUCTS
  • MARKET PARTICIPANTS FOR REAGENTS AND TOOLS FOR EXOSOME RESEARCH
    • SYSTEM BIOSCIENCES (SBI)
    • HANSABIOMED
    • 101BIO
    • EVOMIC SCIENCE
    • AMSBIO
    • CELL GUIDANCE SYSTEMS
    • CILOA
    • EXCYTEX
    • NANOSIGHT
    • IZON SCIENCE
  • EVALUATION OF CURRENT TOOLS AND REAGENTS SECTOR IN EXOSOME MARKET 127
  • TABLE 52 GLOBAL MARKET SIZE OF EXOSOME RESEARCH TOOLS AND REAGENTS MARKET, THROUGH 2021 ($ MILLIONS)
  • FIGURE 7 GLOBAL MARKET SIZE OF EXOSOME RESEARCH TOOLS AND REAGENTS MARKET, 2013-2021 ($ MILLIONS)

CHAPTER 7 PATENT ANALYSIS OF EXOSOME MARKET

  • OVERVIEW
  • TABLE 53 NUMBER OF PATENTS FILED IN SPECIFIC YEARS ON EXOSOME RESEARCH, 2000-2015
  • FIGURE 8 NUMBER OF PATENTS FILED IN SPECIFIC YEARS ON EXOSOME RESEARCH, 2000-2015
  • TABLE 54 EXAMPLES OF PATENTS FILED ON EXOSOME RESEARCH
  • TABLE 55 SEARCH ANALYSIS FOR PATENTS USING SPECIFIC KEYWORDS (NO. OF PATENTS)
  • FIGURE 9 SEARCH ANALYSIS FOR PATENTS USING SPECIFIC KEYWORDS (NO. OF PATENTS)

CHAPTER 8 IMPACT OF EXOSOME RESEARCH ON SPECIFIC BIOPHARMACEUTICALS MARKETS

  • OVERVIEW
    • EXOSOME RESEARCH IMPACT ON BIOMARKER AND DIAGNOSTICS INDUSTRY
    • TABLE 56 EXAMPLES OF PROTEIN MARKERS IN EXOSOMES AND THEIR RELATED PATHOLOGY
    • EXOSOME RESEARCH IMPACT ON MICRORNA MARKET
    • TABLE 57 EXAMPLES OF MICRORNA MARKERS IN EXOSOMES AND THEIR RELATED PATHOLOGY
    • EXOSOME RESEARCH IMPACT ON LIQUID BIOPSY MARKET
    • TABLE 58 LIQUID VS. TISSUE BIOPSY
    • EXOSOME RESEARCH IMPACT ON STEM CELL TECHNOLOGIES MARKET
    • EXOSOME RESEARCH IMPACT ON PRENATAL DIAGNOSTICS MARKET
    • TABLE 59 GLOBAL MARKET VALUE FOR PRENATAL DIAGNOSTICS, PREDICTIVE TESTS AND NEONATAL MONITORING, THROUGH 2019 ($ BILLIONS)

CHAPTER 9 MARKET SUMMARY

  • TABLE 60 GLOBAL MARKET FOR EXOSOME INDUSTRY BY SECTOR, THROUGH 2021 ($ MILLIONS)
  • FIGURE 10 GLOBAL MARKET FOR EXOSOME INDUSTRY BY SECTOR, 2014-2021 ($ MILLIONS)
  • TABLE 61 EXAMPLES OF MAIN MARKET PARTICIPANTS IN EXOSOME MARKET RESEARCH AND DEVELOPMENT

CHAPTER 10 SELECT COMPANIES OVERVIEW

  • AETHLON MEDICAL INC.
  • EXOSOME DIAGNOSTICS INC.
  • NANOSOMIX INC.
  • SYSTEM BIOSCIENCES (SBI)
  • THERMO FISHER SCIENTIFIC INC.
  • YMIR GENOMICS LLC

CHAPTER 11 LIST OF THE COMPANIES MENTIONED IN REPORT

  • 101BIO
  • AEGLE THERAPEUTICS
  • AETHLON MEDICAL INC.
  • AMARANTUS BIOSCIENCE HOLDINGS INC.
  • AMSBIO LLC
  • BIOREGENERATIVE SCIENCES INC.
  • CAPRICOR THERAPEUTICS
  • CARIS LIFE SCIENCES
  • CELL GUIDANCE SYSTEMS LLC
  • CILOA
  • CODIAK BIOSCIENCES
  • DREIROSEN PHARMA
  • EVOMIC SCIENCE LLC
  • EXCYTEX
  • EXIQON, INC
  • EXOCYTE THERAPEUTICS PTE LTD.
  • EXOSOME DIAGNOSTICS INC.
  • EXOSOME SCIENCE
  • EXOSOMICS SIENA SPA
  • EXOVITA BIOSCIENCES
  • HANSABIOMED
  • ITH, IMMUNE THERAPY HOLDINGS AB
  • IZON SCIENCE
  • JSR MICRO INC.
  • MEDISTEM/INTREXON CORP.
  • MILTENYI BIOTEC GMBH
  • NANOSIGHT/MALVERN INSTRUMENTS LTD.
  • NANOSOMIX INC.
  • NEW ENGLAND PEPTIDE INC.
  • NORGEN BIOTEK CORP
  • NX PHARMAGEN
  • ORION PHARMA LTD.
  • PANACEA PHARMACEUTICALS
  • PARADIGM BIOPHARMACEUTICALS
  • PARTICLE METRIX INC.
  • PFIZER
  • PROMEGA CORP.
  • QIAGEN
  • REDERMIS
  • RENEURON GROUP PLC
  • SISTEMIC
  • SYSTEM BIOSCIENCES (SBI)
  • THERAPEUTICS SOLUTIONS INTERNATIONAL
  • THERMOFISHER SCIENTIFIC
  • YMIR GENOMICS LLC

LIST OF TABLES

  • SUMMARY TABLE GLOBAL MARKET FOR EXOSOME INDUSTRY BY SECTOR, THROUGH 2021 ($ MILLIONS)
  • TABLE 1 NOMENCLATURE OF EXOSOME PARTICLES
  • TABLE 2 PUBLICATION TREND ON EXOSOME SUBJECT, 2003-2015 (NO. OF PUBLICATIONS)
  • TABLE 3 STEPS IN EXOSOME BIOGENESIS AND PROCESSING
  • TABLE 4 PROTEINS ESSENTIAL IN EXOSOME BIOGENESIS AND PROCESSING
  • TABLE 5 PROTEINS FOUND IN EXOSOMES
  • TABLE 6 MICRORNA IN DIFFERENT BODILY FLUIDS
  • TABLE 7 METHODS FOR EXOSOME ISOLATION
  • TABLE 8 DISTRIBUTION OF EXOSOMES ISOLATION PROCEDURES IN THE STUDIES CATALOGED IN EXOCARTA (%)
  • TABLE 9 STATISTICS OF DATA CATALOGED IN EXOCARTA, 2012
  • TABLE 10 STATISTICS OF DATA CATALOGED IN VESICLEPEDIA, 2012
  • TABLE 11 STATISTICS OF DATA CATALOGED IN EVPEDIA, 2014
  • TABLE 12 COMPARISON OF DATABASES FOR EXOSOME STUDIES
  • TABLE 13 EXOSOMAL PROTEINS FOR CLINICAL DIAGNOSTIC APPLICATIONS
  • TABLE 14 EXOSOMAL MICRORNA FOR CLINICAL DIAGNOSTIC APPLICATIONS
  • TABLE 15 STATISTICS FOR PROSTATE CANCER, 2015
  • TABLE 16 GLOBAL MARKET VALUE FOR PROSTATE CANCER DIAGNOSTICS AND RELATED COST ($ BILLIONS)
  • TABLE 17 STATISTICS FOR BREAST CANCER, 2015
  • TABLE 18 GLOBAL MARKET VALUE FOR BREAST CANCER DIAGNOSTICS, THROUGH 2019 ($ BILLIONS)
  • TABLE 19 STATISTICS FOR BLADDER CANCER, 2015
  • TABLE 20 GLOBAL MARKET VALUE FOR BLADDER CANCER DIAGNOSTICS, 2015 ($ BILLIONS)
  • TABLE 21 STATISTICS FOR OVARIAN CANCER, 2015
  • TABLE 22 GLOBAL MARKET VALUE FOR OVARIAN CANCER DIAGNOSTICS, 2015 ($ MILLIONS)
  • TABLE 23 STATISTICS FOR LUNG CANCER, 2015
  • TABLE 24 GLOBAL MARKET VALUE FOR LUNG CANCER DIAGNOSTICS, 2015 ($ MILLIONS)
  • TABLE 25 LIQUID VS. TISSUE BIOPSY
  • TABLE 26 GLOBAL MARKET VALUE FOR LIQUID BIOPSY MARKET, 2015 AND 2020 ($ BILLIONS)
  • TABLE 27 U.S. STATISTICS DATA FOR ALZHEIMER'S, 2015 (MILLIONS/$ BILLIONS)
  • TABLE 28 GLOBAL MARKET VALUE FOR ALZHEIMER'S DIAGNOSTICS, 2009 AND 2014 ($ BILLIONS)
  • TABLE 29 GLOBAL STATISTICS DATA FOR HEPATITIS C INFECTION, 2015 (MILLIONS)
  • TABLE 30 GLOBAL MARKET VALUE FOR HEPATITIS C DIAGNOSTICS, 2015 ($ BILLIONS)
  • TABLE 31 U.S. STATISTICS DATA FOR CARDIOVASCULAR DISEASES, 2011
  • TABLE 32 GLOBAL MARKET VALUE FOR CARDIOVASCULAR DIAGNOSTICS, 2015 ($ BILLIONS)
  • TABLE 33 GLOBAL MARKET VALUE FOR PRENATAL DIAGNOSTICS, PREDICTIVE TESTS AND NEONATAL MONITORING, THROUGH 2019 ($ BILLIONS)
  • TABLE 34 COMPARISON OF EXOSOME DIAGNOSTICS APPROACH TO OTHER LIQUID BIOPSY PLATFORMS
  • TABLE 35 GLOBAL MARKET SIZE FOR DIAGNOSTICS EXOSOME MARKET, THROUGH 2021 ($ MILLIONS)
  • TABLE 36 EXAMPLES OF PHYSIOLOGICAL EFFECT OF EXOSOME DELIVERY
  • TABLE 37 TOP FIVE VACCINE PROVIDERS, 2014 ($ BILLIONS)
  • TABLE 38 MARKET FOR AETHLON MEDICAL, 2012-2015 ($ MILLIONS)
  • TABLE 39 U.S. STATISTICS FOR BURN INJURIES, 2015
  • TABLE 40 U.S. STATISTICS FOR PRESSURE ULCER
  • TABLE 41 REVENUE, COST AND PROFITS FOR CAPRICOR THERAPEUTICS, 2011-2014 ($ MILLIONS)
  • TABLE 42 EXAMPLES OF CLINICAL TRIALS IN U.S. USING EXOSOME APPROACH
  • TABLE 43 GLOBAL MARKET SIZE OF THERAPEUTICS EXOSOME MARKET, THROUGH 2021 ($ MILLIONS)
  • TABLE 44 MAIN STEPS IN EXOSOME RESEARCH APPROACH
  • TABLE 45 EXAMPLES OF COMMERCIAL KITS AND REAGENTS FOR EXOSOME ISOLATION
  • TABLE 46 PERCENTAGE OF USE OF EACH ISOLATION TECHNIQUE FOR EXOSOME BY PURIFICATION
  • TABLE 47 EXAMPLES OF DETECTION ASSAY
  • TABLE 48 EXAMPLES OF ANTIBODY PROVIDERS FOR EXOSOME RESEARCH
  • TABLE 49 EXAMPLES OF RNA EXTRACTION COMMERCIAL KITS
  • TABLE 50 USAGE PERCENTAGE OF CHARACTERIZATION TECHNIQUES FOR EXOSOME SAMPLE
  • TABLE 51 EXAMPLES OF PURIFIED EXOSOMES COMMERCIAL PRODUCTS
  • TABLE 52 GLOBAL MARKET SIZE OF EXOSOME RESEARCH TOOLS AND REAGENTS MARKET, THROUGH 2021 ($ MILLIONS)
  • TABLE 53 NUMBER OF PATENTS FILED IN SPECIFIC YEARS ON EXOSOME RESEARCH, 2000-2015
  • TABLE 54 EXAMPLES OF PATENTS FILED ON EXOSOME RESEARCH
  • TABLE 55 SEARCH ANALYSIS FOR PATENTS USING SPECIFIC KEYWORDS (NO. OF PATENTS)
  • TABLE 56 EXAMPLES OF PROTEIN MARKERS IN EXOSOMES AND THEIR RELATED PATHOLOGY
  • TABLE 57 EXAMPLES OF MICRORNA MARKERS IN EXOSOMES AND THEIR RELATED PATHOLOGY
  • TABLE 58 LIQUID VS. TISSUE BIOPSY
  • TABLE 59 GLOBAL MARKET VALUE FOR PRENATAL DIAGNOSTICS, PREDICTIVE TESTS AND NEONATAL MONITORING, THROUGH 2019 ($ BILLIONS)
  • TABLE 60 GLOBAL MARKET FOR EXOSOME INDUSTRY BY SECTOR, THROUGH 2021 ($ MILLIONS)
  • TABLE 61 EXAMPLES OF MAIN MARKET PARTICIPANTS IN EXOSOME MARKET RESEARCH AND DEVELOPMENT

LIST OF FIGURES

  • SUMMARY FIGURE GLOBAL MARKET FOR EXOSOME INDUSTRY BY SECTOR, 2014-2021 ($ MILLIONS)
  • FIGURE 1 PUBLICATION TREND ON EXOSOME SUBJECT, 2003-2015 (NO. OF PUBLICATIONS)
  • FIGURE 2 DIFFERENTIAL CENTRIFUGATION PROCESS
  • FIGURE 3 CILIATED POROUS DEVICE DESIGNED TO ISOLATE EXOSOMES BY FILTRATION
  • FIGURE 4 SIEVING MODELS FOR EXOSOME FILTRATION
  • FIGURE 5 GLOBAL MARKET SIZE FOR DIAGNOSTICS EXOSOME MARKET, 2014-2021 ($ MILLIONS)
  • FIGURE 6 GLOBAL MARKET SIZE OF THERAPEUTICS EXOSOME MARKET, 2014-2021 ($ MILLIONS)
  • FIGURE 7 GLOBAL MARKET SIZE OF EXOSOME RESEARCH TOOLS AND REAGENTS MARKET, 2013-2021 ($ MILLIONS)
  • FIGURE 8 NUMBER OF PATENTS FILED IN SPECIFIC YEARS ON EXOSOME RESEARCH, 2000-2015
  • FIGURE 9 SEARCH ANALYSIS FOR PATENTS USING SPECIFIC KEYWORDS (NO. OF PATENTS)
  • FIGURE 10 GLOBAL MARKET FOR EXOSOME INDUSTRY BY SECTOR, 2014-2021 ($ MILLIONS)
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