Abstract
REPORT HIGHLIGHTS
THIS REPORT CONTAINS:
An overview of the U.S. market for separation systems for commercial
biotechnology Analyses of market trends, with data from 2010, estimates for
2011, and projections of compound annual growth rates (CAGRs) through 2016 A
breakdown of the separation systems for the commercial biotechnology market
into major segments of liquid chromatography, centrifugation, membrane
filtration, electrophoresis, and niche separations Discussion of important
technology and the latest advancements in the industry Evaluations of
important and upcoming patents Company profiles of the top players within the
industry.
REPORT SCOPE
INTRODUCTION
STUDY GOALS AND OBJECTIVES
This market research report provides a comprehensive sizing, analysis, and
forecast of the global market for the commercial applications of biotechnology
separation systems.
The report will review global markets for biotechnology separation systems and
will forecast trends and sales in these markets through 2016. This report
provides a range of information, including detailed analyses of the various
segments of the market, new applications for separation technology, and
overall industry trends. It examines the separation process for a variety of
biomolecules, including; proteins, RNA, and DNA. This information will allow
the reader to evaluate and quantify the current market size for specific
separation systems within the growing biomedical and pharmaceutical technology
market.
Forecasts and trends have been developed from a variety of data, including
industry sources, company publications, and industry benchmarks. Major
separation applications, technologies, geography, and factors influencing the
demand for endoscopy services and products will be discussed. Consideration
is given to an analysis of government issues versus the biotech and
pharmaceutical industry markets.
REASONS FOR DOING THE STUDY
The biomolecule separation market is positioned for significant growth in the
next 5 years. This is due to new protein and other biomolecule products that
will require separation technology, as well as new innovations in the
technology itself. This report investigates one of the major drivers for the
separations system market: the development by the biomedical and
pharmaceutical industry of proteins that can be used as biotherapeutic agents
against a number of human diseases. Another factor that will contribute to
growth is the recognition of this technology in emerging markets such as Japan
and the Pacific Rim countries. Continued global growth is expected due to a
growing middle class in countries such as India, China, Brazil, and Russia.
This report addresses critically important topics for analyzing a changing
market dynamic; identifies the emerging players; discusses the technologies
and strategies for accessing these emerging markets; and notes the measurement
and forecast of specific segments and geographies to allow for enhanced
resources allocation.
SCOPE OF REPORT
Current and projected protein and biomolecule separation revenue forecasts
during the forecast period (i.e., 2010 to 2016) are discussed. Protein
separation systems are playing important roles in new biopharmaceutical
development. Protein separation systems do not require U.S. Food and Drug
Administration (FDA) approval, but the products produced from these processes
do, and they must be produced in accordance with FDA good manufacturing
practices (GMP) guidelines. Thus, these separation procedures and equipment
must pass FDA audits of the manufacturing process. New products requiring
separation technologies that have been approved by the FDA in 2009 and 2010
are covered, and those products expected to be approved within the forecast
period are discussed. Due to the timing of the writing of this report, the
figures for 2011 are estimated except where actual results have been reported
The report includes analysis of the leading competitors, as well as emerging
companies in the current global biomolecule separation market. Profiles of
the manufacturers of the leading products are analyzed, and their specific
product strategies are outlined. This report notes companies that are poised
to introduce new products during the forecast period and discusses how these
products may change the face of the competitive environment. This competitive
environment is examined, with a special focus on the ways in which developing
products and technologies are influencing the current standard of patient
care. Detailed profiles of the current market leaders and emerging companies
are discussed in detail.
Market figures are based on revenues at the manufacturers' level. The base
year for analysis and projection is 2010. Trends are assessed based on a
number of parameters, including projected sales for existing products, new
product introductions, and expanded indications for existing products.
This report also includes overviews and forecasts of the separations market by
product, by company, and by geographic region for the period from 2010 to
2016. The global market is analyzed, and data are provided for each segment.
Sales figures are reported in U.S. dollars and reflect currency fluctuations
within the performance of revenue change. Revenue figures do not account for
variation in local currencies.
All market share data are presented on a global basis unless specifically
noted.
INTENDED AUDIENCE
This report is an invaluable tool for business planners, acquisitions
specialists; licensing strategists; product managers; market research
analysts; investors; investor consultants; and anyone interested in the
biomolecule separation market, its products, its industry participants, and
its future.
It is important to identify overall market trends, product opportunities,
emerging geographies, merger and acquisition opportunities, and insights that
provide guidance for sales growth and business decisions for a variety of
reasons, including:
- Established companies in the industry, including departments that
specialize in corporate strategy, sales and marketing, business development,
and research and development (R&D), will benefit from the contents of this
report.
- Emerging biotechnology players must understand specific opportunities for
out-licensing that originates from the differentiation of their products or
technologies, as compared with leading, competitive, and emerging
technologies. In addition, market forecasts found in this study are supported
in detail.
- Investment firms evaluating candidates for venture capital or investment
in hedged funds will gain insight into the opportunities and risks that are
encountered in the industry with product and company-specific analyses.
- Equity analysts are provided with detailed forecasts for the next 5 years,
which are substantiated by quantitative analysis that can support further
analysis to product and company forecasts over the short and long run.
ANALYST CREDENTIALS
Jackson Highsmith is a life sciences research consultant with more than 16
years of research experience. Jackson has been consulting with specialty
pharmaceuticals and large pharmaceutical industry players since 2007. Prior
to that, he worked at a large research consultancy, where he focused on
in-depth research; he also has worked at a large pharmaceutical company in a
wide range of medical therapeutics in early- and mid-stage drug development.
METHODOLOGY AND INFORMATION SOURCES
Both primary and secondary research methodologies were used in preparing this
report. In-depth interviews were conducted with leading experts in the field,
including company executives, industry analysts, and leading biotechnology
investigators.
The overall biomolecule separation sector is comprised of a variety of fast -
growing, independent segments. For completeness, the current and forecasted
markets comprise the total market for each respective segment. Within each
sub-section, there is a detailed forecast of each market driver or relevant
area of growth.
The information used in preparing this report was obtained from emerging
companies in the biomolecule separation industry, including their annual
reports, 10Ks, press releases, websites, and other company documents.
Information also came from articles published in research journals, such as
the Belfort' s Biomolecular Separations Research Group, NUS Membrane
Research-Bio Separation, Lab-on-a-Chip Technology, Nature Methods, and Trends
in Biotechnology. Other information was gathered from the World Health
Organization and biotechnology associations. Population estimates are based
on those reported by the U.S. Census Bureau' s international database.
Investigated articles appeared in various journals focusing on biotechnology
and bioprocessing.
Current and historical revenue figures for individual products have been
acquired from company disclosures that exist in the public domain or from
government sources.
Table of Contents
Chapter- 1: INTRODUCTION - Complimentary
- STUDY GOALS AND OBJECTIVES
- REASONS FOR DOING THE STUDY
- SCOPE OF REPORT
- INTENDED AUDIENCE
- ANALYST CREDENTIALS
- METHODOLOGY AND INFORMATION SOURCES
- RELATED REPORTS
- BCC ONLINE SERVICES
- DISCLAIMER
Chapter- 2: SUMMARY
- Table 0 : GLOBAL MARKET FOR COMMERCIAL BIOTECH SEPARATION SYSTEMS BY
METHOD OF SEPARATION, THROUGH 2016
- Figure 0 : GLOBAL MARKET FOR COMMERCIAL BIOTECH SEPARATION SYSTEMS BY
METHOD OF SEPARATION, 2011 AND 2016
Chapter- 3: OVERVIEW
- BIOMOLECULAR SEPARATION SYSTEMS
- RED BIOTECHNOLOGY
- WHITE BIOTECHNOLOGY
- GREEN BIOTECHNOLOGY
- BLUE BIOTECHNOLOGY
- ANALYTICAL, PREPARATIVE, AND PRODUCTION SCALE PROCESSES
- BIOMOLECULAR SEPARATIONS AND PURIFICATION
- SEPARATION TECHNOLOGY: CURRENT TRENDS
- DRIVERS AND RESISTORS FOR BIOMOLECULAR SEPARATION MARKET
- COMMERCIAL BIOMOLECULAR SEPARATION MARKET
- COMMERCIAL SEPARATION SYSTEMS END-USE MARKETS
- COMMERCIAL BIOTECHNOLOGY SEPARATION SYSTEMS END-USER DISTRIBUTION WITHIN
THE U.S. MARKET
- DISTRIBUTION OF SEPARATIONS SYSTEMS BY END USERS
- OVERVIEW OF THE GLOBAL COMMERCIAL BIOMOLECULAR SEPARATIONS MARKET
- OVERVIEW OF GLOBAL MARKET SEPARATION SYSTEMS GROWTH BY SEPARATION METHOD
- SEPARATION SYSTEMS MARKET: COMPETITIVE STRUCTURE
- Table 7 : COMPETITIVE STRUCTURE, 2010
Chapter- 4: CENTRIFUGATION SYSTEMS IN BIOTECHNOLOGY
- TYPES OF CENTRIFUGATION PROCEDURES
- APPLICATIONS OF CENTRIFUGATION IN SEPARATION
- DRIVERS FOR CENTRIFUGATION SYSTEMS IN THE BIOTECH INDUSTRY
- KEY PLAYERS IN THE CENTRIFUGATION SEPARATION SYSTEMS GLOBAL MARKET
Chapter- 5: LIQUID CHROMATOGRAPHY IN BIOMOLECULAR SEPARATIONS IN BIOTECHNOLOGY
- ION EXCHANGE CHROMATOGRAPHY
- GEL FILTRATION CHROMATOGRAPHY
- AFFINITY CHROMATOGRAPHY
- THIN-LAYER CHROMATOGRAPHY
- FLASH CHROMATOGRAPHY
- HIGH - PERFORMANCE, THIN-LAYER CHROMATOGRAPHY
- APPLICATIONS OF LIQUID CHROMATOGRAPHY IN THE GLOBAL BIOMOLECULAR
SEPARATIONS INDUSTRY
- DRIVERS OF LIQUID CHROMATOGRAPHY IN THE BIOMOLECULAR SEPARATION INDUSTRY
- MARKET ANALYSIS OF THE GLOBAL LIQUID CHROMATOGRAPHY BIOTECH INDUSTRY
THROUGH 2011
- Table 14 : GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY SYSTEMS BY REGION,
THROUGH 2016
- Table 15 : GLOBAL MARKET FOR CHROMATOGRAPHY SYSTEMS BY TECHNOLOGY,
THROUGH 2016
- Table 16 : KEY PLAYERS IN THE LIQUID CHROMATOGRAPHY SEPARATION SYSTEMS
MARKET, 2010
Chapter- 6: ELECTROPHORESIS IN BIOMOLECULAR SEPARATIONS
- TYPES OF ELECTROPHORESIS
- APPLICATION OF ELECTROPHORESIS IN THE BIOMOLECULAR SEPARATIONS INDUSTRY
- DRIVERS OF ELECTROPHORESIS IN THE BIOMOLECULAR SEPARATIONS INDUSTRY
- KEY PLAYERS IN ELECTROPHORESIS SEPARATION SYSTEMS GLOBAL MARKET
Chapter- 7: MEMBRANE FILTRATION IN BIOMOLECULAR SEPARATIONS
- MATERIAL COMPOSITION OF MEMBRANE FILTERS
- CROSS-FLOW AND TANGENTIAL FLOW FILTRATION
- BIOMOLECULAR FILTRATION CONFIGURATIONS
- ADVANTAGES OF MEMBRANE SYSTEMS
- DISADVANTAGES OF MEMBRANE SYSTEMS
- APPLICATION OF MEMBRANE FILTRATION TO THE BIOMOLECULAR SEPARATIONS INDUSTRY
- DRIVERS OF MEMBRANE FILTRATION IN THE BIOMOLECULAR SEPARATIONS INDUSTRY
- MARKET ANALYSIS OF MEMBRANE FILTRATION IN THE BIOMOLECULAR SEPARATIONS
INDUSTRY THROUGH 2016
- KEY PLAYERS IN THE GLOBAL MARKET FOR MEMBRANE FILTRATION SEPARATION SYSTEMS
Chapter- 8: NEW METHODS OF BIOMOLECULAR SEPARATION
- MICROARRAY AND LAB-ON-A-CHIP
- FLOW CYTOMETRY
- MAGNETIC SEPARATION
- Table 21 : GLOBAL MARKET FOR NEW SEPARATION METHODS BY REGION, THROUGH
2016
- Table 22 : MARKET FOR NEW SEPARATIONS METHODS, THROUGH 2016
- Table 23 : KEY PLAYERS IN EACH OF THE NEW SEPARATIONS MARKET SEGMENTS
Chapter- 9: COMPANY PROFILES
- AFFYMETRIX
- AGILENT TECHNOLOGIES
- ALFA LAVAL GROUP
- ALFA WASSERMANN SEPARATION TECHNOLOGIES
- APPLIED BIOSYSTEMS CORPORATION
- BECKMAN COULTER, INC.
- BD BIOSCIENCES (BECTON, DICKINSON, AND COMPANY)
- BIO-RAD LABORATORIES, INC.
- CALIPER LIFE SCIENCES
- DIONEX
- FLOTTWEG SEPARATIONS TECHNOLOGY
- GE HEALTHCARE LIFE SCIENCES
- HITACHI KOKI CO., LTD.
- INVITROGEN
- LIFE TECHNOLOGIES
- MILLIPORE BIOMANUFACTURING AND LIFE SCIENCES (MERCK KGAA)
- NOVASEP LIFE SCIENCES MANUFACTURING SOLUTIONS
- PALL CORPORATION
- PERKIN-ELMER
- QIAGEN GMBH
- SEPMAG TECHNOLOGIES
- SARTORIUS STEDMAN BIOTECH CORPORATION
- SHIMADZU SCIENTIFIC INSTRUMENTS
- TECAN GROUP, LTD.
- THERMO FISHER SCIENTIFIC
- WATERS CORPORATION
- WHATMAN INTERNATIONAL, LTD.
Chapter- 10: PATENTS FOR BIOMOLECULAR SEPARATIONS-RELATED INSTRUMENTATION AND ACCESSORIES
- Table 24 : PATENTS ISSUED FOR BIOMOLECULAR SEPARATIONS TECHNOLOGIES, 2005
- 2010
- Table 25 : U.S. AND E.U. BIOMOLECULAR SEPARATIONS PATENTS BY AREA
- Table 26 : BIO-RAD LABORATORIES PARTIAL U.S. PATENT LIST
- Table 27 : AGILENT TECHNOLOGIES PARTIAL U.S. PATENT LIST
- Table 28 : GE HEALTHCARE LIFE SCIENCES PARTIAL U.S. PATENT LIST
- Table 29 : WATERS CORPORATION PARTIAL U.S. PATENT LIST
- Table 30 : MERCK MILLIPORE CORPORATION PARTIAL U.S. PATENT LIST
- Table 31 : GLOBAL CHROMATOGRAPHY PATENTS
- Table 32 : MEMBRANE FILTRATION PATENTS
- Table 33 : ELECTROPHORESIS PATENTS
Chapter- 11: APPENDIX
- Table 34 : KEY WEBSITES
- Table 35 : KEY INDUSTRY AND REGULATORY ASSOCIATIONS
List of Tables
- Summary Table : GLOBAL MARKET FOR COMMERCIAL BIOTECH SEPARATION SYSTEMS BY
METHOD OF SEPARATION, THROUGH 2016
- Table 1 : GLOBAL MARKET RANKING FOR COMMERCIAL BIOTECH SEPARATION SYSTEMS,
2011 AND 2016
- Table 2 : MAJOR COMPANIES IN THE BIOMOLECULAR SEPARATION MARKET AND MAJOR
PRODUCT AREAS, 2011
- Table 3 : GLOBAL MANUFACTURE OF BULK CHEMICAL SUBSTANCE BY BIOCATALYSIS,
2010
- Table 4 : DISTRIBUTION OF U.S. BIOTECHNOLOGY AND BIOPHARMA COMPANIES BY
REGION, 2008
- Table 5 : GLOBAL MARKET FOR BIOMOLECULAR SEPARATIONS SYSTEMS INDUSTRY BY
REGION, THROUGH 2016
- Table 6 : GLOBAL MARKET FOR SEPARATION SYSTEMS BY SEPARATION METHOD,
THROUGH 2016
- Table 7 : COMPETITIVE STRUCTURE, 2010
- Table 8 : ACQUIRED BIOTECHNOLOGY AND BIOPHARMACEUTICAL COMPANIES, 2008 -
2010
- Table 9 : CENTRIFUGATION PROCESSES AND CHEMICALS USED
- Table 10 : GLOBAL MARKET FOR CENTRIFUGATION SEPARATION SYSTEMS BY REGION,
THROUGH 2016
- Table 11 : CENTRIFUGATION SEPARATION SYSTEMS MARKET, THROUGH 2016
- Table 12 : PRODUCT TECHNOLOGY IN ULTRACENTRIFUGATION BY COMPANY, 2011
- Table 13 : PRODUCT TECHNOLOGY IN CHROMATOGRAPHY BY COMPANY, 2011
- Table 14 : GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY SYSTEMS BY REGION,
THROUGH 2016
- Table 15 : GLOBAL MARKET FOR CHROMATOGRAPHY SYSTEMS BY TECHNOLOGY, THROUGH
2016
- Table 16 : KEY PLAYERS IN THE LIQUID CHROMATOGRAPHY SEPARATION SYSTEMS
MARKET, 2010
- Table 17 : GLOBAL MARKET FOR ELECTROPHORESIS SYSTEMS BY REGION, THROUGH
2016
- Table 18 : GLOBAL MARKET FOR ELECTROPHORESIS SYSTEMS BY METHOD, THROUGH
2016
- Table 19 : CLASSES OF FILTRATION BY PORE SIZE AND APPLICATION
- Table 20 : GLOBAL MARKET FOR MEMBRANE FILTRATION SYSTEMS BY REGION,
THROUGH 2016
- Table 21 : GLOBAL MARKET FOR NEW SEPARATION METHODS BY REGION, THROUGH 2016
- Table 22 : MARKET FOR NEW SEPARATIONS METHODS, THROUGH 2016
- Table 23 : KEY PLAYERS IN EACH OF THE NEW SEPARATIONS MARKET SEGMENTS
- Table 24 : PATENTS ISSUED FOR BIOMOLECULAR SEPARATIONS TECHNOLOGIES, 2005
- 2010
- Table 25 : U.S. AND E.U. BIOMOLECULAR SEPARATIONS PATENTS BY AREA
- Table 26 : BIO-RAD LABORATORIES PARTIAL U.S. PATENT LIST
- Table 27 : AGILENT TECHNOLOGIES PARTIAL U.S. PATENT LIST
- Table 28 : GE HEALTHCARE LIFE SCIENCES PARTIAL U.S. PATENT LIST
- Table 29 : WATERS CORPORATION PARTIAL U.S. PATENT LIST
- Table 30 : MERCK MILLIPORE CORPORATION PARTIAL U.S. PATENT LIST
- Table 31 : GLOBAL CHROMATOGRAPHY PATENTS
- Table 32 : MEMBRANE FILTRATION PATENTS
- Table 33 : ELECTROPHORESIS PATENTS
- Table 34 : KEY WEBSITES
- Table 35 : KEY INDUSTRY AND REGULATORY ASSOCIATIONS
List of Figures
- Summary Figure : GLOBAL MARKET FOR COMMERCIAL BIOTECH SEPARATION SYSTEMS
BY METHOD OF SEPARATION, 2011 AND 2016
