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市場調查報告書

細胞化驗分析:各種技術及全球市場

Cell-based Assays: Technologies and Global Markets

出版商 BCC Research 商品編碼 196807
出版日期 內容資訊 英文 219 Pages
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細胞化驗分析:各種技術及全球市場 Cell-based Assays: Technologies and Global Markets
出版日期: 2017年07月13日 內容資訊: 英文 219 Pages
簡介

全球細胞化驗分析市場從2016年到2021年間,預測將以10.6%的年複合成長率 (CAGR) 推移,規模從2015年的152億美元,成長到2016年的171億美元,2021年的284億美元。

本報告提供細胞化驗分析的技術與市場調查,提供細胞化驗分析定義和概要,結構技術·相關技術趨勢,相關技術·工具·試劑的市場規模的變化與預測,主要地區·各國的趨勢,專利情形,並彙整主要企業的簡介等資訊。

第1章 簡介

第2章 摘要·亮點

第3章 概要

  • 簡介
  • 藥物研發
  • 概要:細胞化驗分析
  • 藥物研發工具
    • 高內容篩選
    • 細胞型篩檢
    • 增生化驗
    • 細胞化驗分析的概念驗證
    • 細胞化驗分析及技術趨勢

第4章 藥物研發的細胞化驗分析

  • ADME/TOX篩檢的細胞型方法
    • 市場機會
    • ADME·毒性篩檢
    • 多重陣列細胞化驗分析
    • 細胞型生物邏輯化驗
    • 細胞化驗分析高通量成像型的平台
    • 無標記細胞測定:藥物研發和相關未來
  • 總論

第5章 細胞化驗分析:目前技術

  • 開發細胞化驗分析的影響因素
  • 報導基因技術
  • 蛋白質間相互作用的研究上細胞化驗分析
  • 細胞型的相互作用檢測法 (PCA:Protein-fragment Complementation Assay)
  • 鈣信號的檢測
  • 細胞型免標定方法
  • 自動化·小型化
  • 電池單元圖形化
  • 細胞化驗分析與生理的相關性
  • 細胞化驗分析與多重化
  • 超高通量篩選
  • PATHHUNTER化驗的開發
  • 高內容篩選技術
  • 開發藥劑中臨床實驗藥(IND)研究
  • 前驅藥物策略
  • 分子模擬
  • 摘要
  • 新技術
  • 總論

第6章 細胞化驗分析的商業化

  • 細胞化驗分析所扮演的角色
    • 藥物研發·細胞化驗分析
    • 市場引進的機會
    • 細胞增生的檢測
    • 提供細胞生長化驗企業
    • 趨向透過幹細胞·免疫細胞的治療趨勢
    • 細胞型篩檢化驗
    • 孤兒受體
  • 摘要

第7章 全球細胞化驗分析及儀器市場

  • 目前市場概要
  • 細胞化驗分析
  • 細胞化驗分析市場
  • 電池單元生物學試劑
  • 高通量篩檢
  • 藥物研發技術市場
  • 生命科學工具&試劑的市場
  • 細胞培養市場
  • 細胞培養試劑的全球市場
  • 細胞化驗分析市場成長
  • 基礎研究細胞分析市場
  • ADME·毒物學市場
  • 藥物研發細胞化驗分析
  • ADME-毒物檢驗市場
  • 細胞化驗分析的各種類型
  • 高內容篩選設備市場
  • 免標定檢測市場
  • 微孔盤用設備·消耗品
  • 細胞化驗造成分析的變化
  • 細胞化驗分析的未來性
  • 研究目的細胞化驗分析
  • 細胞化驗分析:離子通道的篩檢
  • 免標定檢測
  • 總論

第8章 市場分析:各地區

  • 全球市場
  • 摘要
  • 美國
  • 歐洲
  • 新興經濟圈的藥物研發
  • 細胞化驗分析的演進

第9章 企業簡介

第10章 細胞化驗分析法律面

  • 智慧財產權狀況

第11章 參考資料

圖表

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目錄
Product Code: BIO080C

The global market for cell-based assays reached $15.2 billion in 2015. This market is expected to increase from $17.1 billion in 2016 to nearly $28.4 billion in 2021 at a compound annual growth rate (CAGR) of 10.6% for 2016-2021.

Report Includes

  • An overview of the global markets and related technologies for cell-based assays.
  • Analyses of global market trends, with data from 2015 and 2016, and projections of compound annual growth rates (CAGRs) through 2021.
  • Examinations of major issues involved in the research and development (R&D) of more effective cell-based approaches, for drug discovery and absorption, distribution, metabolism, and excretion (ADME)/ toxicity assays in development and in use.
  • The current market status of cell-based assays in terms of strengths, weaknesses, opportunities and threats facing various assays and developments already on the market.
  • Discussion of current issues and trends affecting the industry, and costs and other factors influencing demand.
  • Coverage of new technologies, trends, alliances, and mergers.
  • Profiles of major players in the industry.

Report Scope

This report is an update on the earlier report: Cell-based Assays: Technologies and Global Markets. It reviews global markets for cell-based assays and new developments and forecasts trends for use of these assays for drug discovery, safety and toxicology through 2021. The report includes important assays, technologies and the latest developments and market share by assay type and company, with a special emphasis on the U.S. market. Statistical information on the types of cancers prevalent worldwide is also included. The report also includes current issues and trends affecting the industry, costs and factors influencing demand. It covers products in development, new technologies, trends, and alliances and mergers. The report offers market data by segment and region. It also provides market trends with respect to drivers, restraints and opportunities.

Analyst Credentials

Usha Nagavarapu is an experienced pharmaceutical professional with business development experience. She has preclinical, alliance management, discovery and technology development and marketing experience. Her strong focus areas include oncology and cardiovascular disease, with expertise in molecular and cell biology and complex cell-based biological assays for drug discovery, in vitro and in vivo screening, in vivo model development and pharmacokinetics. She has experience working with early start-ups.

Table of Contents

Chapter 1: Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Intended Audience
  • Methodology
  • Geographic Breakdown
  • Analyst's Credentials
  • Related BCC Research Reports

Chapter 2: Summary and Highlights

Chapter 3: Overview

  • Introduction
  • Drug Discovery
    • High-content Screening
    • Data Analysis
  • Overview: Cell-based Assays
  • Tools for Drug Discovery
    • High-content Screening
    • Cell-based Screening
    • Proliferation Assays
    • Proof of Concept for Cell-based Assays
    • Cell-based Assays and Technology Trends

Chapter 4: Assays for Drug Discovery

  • Cell-based Approaches for ADME/Tox Screening
    • Market Opportunity
    • ADME and Toxicity Screening
    • Multiplexed Cell-based Assays
    • Cell-based Biological Assays
    • High-throughput Imaging-based Platform for Cell-based Assays
    • Cell Assays in Today's Drug Discovery Process
    • Label-free Cellular Assays: The Relevant Future of Drug Discovery
  • Conclusions

Chapter 5: Cell-based Assays: Current Technologies

  • Factors in Cell-based Assay Development
  • Reporter Gene Technology
  • Cell-based Assays for Studying Protein-Protein Interactions
  • Cell-based Protein-Fragment Complementation Assays
  • Measuring Calcium Signaling
  • Cell-based Label-free Approaches
  • Automation and Miniaturization
  • Cell Patterning
  • Cell-based Assays and Physiological Relevance
  • Cell-based Assays and Multiplexing
    • Developing Reporter Assays
    • Reporter Assays and Multiplexing
  • Ultra-high-throughput Screening
  • Development of PathHunter Assay
  • High-content Screening Technology
    • Imaging Cells for Cell-based Assays
    • Microscopic Visualization of Cells
    • Quantum Dots
    • Label-free Imaging
  • Investigational New Drug (IND) Studies in Drug Development
    • Role of ADME in Drug Design
  • Prodrug Strategies
  • Molecular Modeling
  • Summary
    • Limitations of Cell-based Assays in the Process of Risk Assessment
    • Bottlenecks in Cell-based Screening.
    • Methods to Improve Throughput in Cell-based Assays
  • New Technologies
    • DataChip
    • BIND Technology
    • Miniaturization of Biological Assays
    • Microfluidic Cell Culture Systems for Drug Research
  • Conclusion

Chapter 6: Commercialization of Cell-based Assays

  • Role of Cell-based Assays
    • Drug Discovery and Cell-based Assays
    • Opportunities for Market Adoption
    • Measuring Cell Proliferation
    • Companies Offering Cell Proliferation Assays
    • Move Toward Therapies with Stem and Immune Cells
    • Cell-based Screening Assays
    • Orphan Receptors
  • Summary

Chapter 7: Global Cell-based Assay and Instrumentation Market

  • Current Market Overview
  • Cell-based Assays
  • Cell-based Assay Market
    • Market Dynamics
    • Market Drivers
    • Cell-based Assays for Preclinical Development
  • Cell Biology Reagents
  • High-throughput Screening
    • Advantages of HTS Assays
    • Major Drivers
  • Drug Discovery Technology Market
  • Market for Life Sciences Tools and Reagents
  • Cell Culture Market
    • Cell Culture Reagent Market
  • Global Market for Cell Culture Reagents
    • Three-dimensional Cell Culture Market
  • Cell-based Assays Market Growth
    • Market Demand
  • Cell-based Assays: Basic Research
  • Market for Cellular Assays in Basic Research.
    • GE Healthcare and Products
    • Cell Proliferation Fluorescence Assay
    • In vitro Toxicity Testing
    • In vitro Skin Irritation Testing
  • ADME and Toxicology Market
    • In vitro Predictive Toxicology
  • Cell-based Assays for Drug Discovery
  • ADME-Toxicology Testing Market
    • DiscoverX
    • ADME: Tools and Technologies
    • ADME Studies for FDA Submissions
    • Market Players
    • New Developments
    • In vitro Inflammation Models
    • Multiplex Assays for GPCR Signaling
  • Types of Cell-based Assays
    • HCS Market Drivers
    • Molecular Devices
    • High-Content Screening Kits
  • High-content Screening Instrumentation Market
    • Flow Cytometers
  • Label-free Detection Market
  • Microplate Instrumentation and Supplies
  • Challenges with Cell-based Assays
  • Future of Cell-based Assays
  • Cell-based Assays for Research Purposes
    • G Protein-Coupled Receptors
    • Key Facts
  • Cell-based Assays: Screening Ion Channels
  • Label-free Detection
    • Companies
    • CellSensor Assays
    • LanthaScreen Assays
    • Molecular Devices
  • Conclusion

Chapter 8: Global Regional Markets

  • Global Market for Cell-based Assays
    • Cell-based Assays in the Leading Emerging Markets
  • Summary
  • U.S. Market
  • Global Market Overview
  • European Market
  • Drug Discovery in the Emerging Economies
    • Drug Discovery in India and China
  • Advances in Cell-based Assays
    • Contract Research Organizations and Cell-based Assays
    • Outlook

Chapter 9: Company Profiles

Chapter 10: Legal Aspects of Cell-based Assays

  • Intellectual Property Landscape for Cell-based Assays
    • Latest News, Alliances and Mergers
    • Label-free Technologies
    • Summary and Outlook

Appendix: Bibliography

About BCC Research

  • About BCC Research
  • BCC Membership
  • BCC Custom Research

List of Tables

  • Summary Table: Global Market for Cell-based Assays, Through 2021 ($ Millions)
  • Table 1 Cell-Based Assays and Uses
  • Table 2 Types of Cell-based Assays
  • Table 3 Apoptotic Markers
  • Table 4 Proof-of-Concept for Cell-based Assays
  • Table 5 Global Market and Forecast for Cell-based Assays, Through 2021 ($ Millions)
  • Table 6 Biological Assay Systems for the Evaluation of Cytochrome P450 Enzyme Isoforms
  • Table 7 Hepatocyte Assay Systems
  • Table 8 ADME Assays
  • Table 9 Common Toxicity Assays
  • Table 10 Traditional Methods of ADME/Tox Testing
  • Table 11 Conventional in vitro ADME/Tox Screening Methods
  • Table 12 Label-free Assays and Applications
  • Table 13 Factors for Cell-based Assay Development
  • Table 14 Approaches to Cell-based Systems for Drug Screening
  • Table 15 Current Confocal HCS Platforms
  • Table 16 Widefield HCS Platforms
  • Table 17 Studies for Filing an IND
  • Table 18 Studies for Clinical Filings
  • Table 19 Existing Technologies
  • Table 20 Biological Applications for HCA
  • Table 21 Global Market for Cell Biology Reagents and Tools, Through 2021 ($ Millions)
  • Table 22 Global HTS Market, Through 2021 ($ Millions)
  • Table 23 HTS Technologies: Key Companies
  • Table 24 Global Market for Drug Discovery Technologies, Through 2021 ($ Millions)
  • Table 25 Key Companies for Drug Discovery Technologies
  • Table 26 Global Market for Reagents and Tools Used in Life Sciences Research, Through 2021 ($ Millions)
  • Table 27 Global Market for Cell Culture, Through 2021 ($ Millions)
  • Table 28 Global Cell Culture Reagent Types
  • Table 29 Global Market for Cell Culture Reagents, Through 2021 ($ Millions)
  • Table 30 U.S. Market for Cell Culture, Through 2021 ($ Millions)
  • Table 31 Global Market for 3D Cell Culture, Through 2019 ($ Millions)
  • Table 32 3D Cell Culture
  • Table 33 Cell-based Assay companies
  • Table 34 Cell-based Assay Market
  • Table 35 Global Market for Cell-Based Assays, Through 2021 ($ Millions)
  • Table 36 Limitations of Cell-Based Assays
  • Table 37 Global Market for Cell-based Assays Used in Basic Research, Through 2021 ($ Millions)
  • Table 38 In vitro Toxicology Testing
  • Table 39 Global 3D Cell Culture, Through 2021 ($ Millions)
  • Table 40 Global Market for Specialized Cell-based Assays used in Drug Discovery, Through 2021 ($ Millions)
  • Table 41 In vitro Predictive Toxicology Assays
  • Table 42 3D Microtissue and Spheroid Models
  • Table 43 Global Market for ADME Assays, Through 2021 ($ Millions)
  • Table 44 Key Companies
  • Table 45 HCS Market: Major Companies
  • Table 46 Molecular Devices: Products
  • Table 47 HCS System Platforms
  • Table 48 Millipore Products: Applications
  • Table 49 Global Market for High-content Screening Instruments, Through 2018 ($ Millions)
  • Table 50 Key Flow Cytometry Companies
  • Table 51 Key GPCR-targeting Drugs
  • Table 52 Key Companies with GPCR Products
  • Table 53 Omeros: GPCRs and Indications
  • Table 54 Assay Methods to Study GPCRs
  • Table 55 GPCR Primary Screening Assays
  • Table 56 Thermo Fisher's Products
  • Table 57 Thermo Fisher's Cell-based Technologies
  • Table 58 Global Market for Cell-based Assays, by Region, Through 2021 ($ Millions)
  • Table 59 U.S. Market for Cell-based Assays, Through 2021 ($ Millions)
  • Table 60 Key Growth Drivers of the Market for Cell-based Assays
  • Table 61 European Market for Cell-based Assay, Through 2021 ($ Millions)
  • Table 62 Chinese Drug Discovery Outsourcing Market, Through 2021 ($ Millions)
  • Table 63 Indian Drug Discovery Market, Through 2021 ($ Millions)

List of Figures

  • Summary Figure: Global Market for Cell-based Assays, 2015-2021 ($ Millions)
  • Figure 1 Drug Discovery Process and Steps
  • Figure 2 Global Market and Forecast for Cell-based Assays, 2015-2021 ($ Millions)
  • Figure 3 Global Market for Cell Biology Reagents and Tools, 2012-2021 ($ Millions)
  • Figure 4 Global Market for Drug Discovery Technologies, 2013-2021 ($ Millions)
  • Figure 5 Global Market for Reagents and Tools used in Life Sciences Research, 2016 and 2021 ($ Millions)
  • Figure 6 Global Market for Cell Culture, 2013-2021 ($ Millions)
  • Figure 7 Global Market for Cell Culture Reagents, 2013-2021 ($ Millions)
  • Figure 8 U.S. Market for Cell Culture, 2013-2021 ($ Millions)
  • Figure 9 Global Market for 3D Cell Culture Reagents, 2013-2019 ($ Millions)
  • Figure 10 Global Market for Cell-Based Assays, 2013-2021 ($ Millions)
  • Figure 11 Global Market for Cell-based Assays Used in Basic Research, 2013-2021 ($ Millions)
  • Figure 12 Global 3D Cell Culture, 2016 and 2021 ($ Millions)
  • Figure 13 Global Market for Specialized Cell-based Assays used in Drug Discovery, 2013-2021 ($ Millions)
  • Figure 14 Global Market for ADME Assays, 2013-2021 ($ Millions)
  • Figure 15 Global Market for High-content Screening Instruments, 2013 and 2018 ($ Millions)
  • Figure 16 Global Market for Cell-Based Assays, by Region, 2013-2021 ($ Millions)
  • Figure 17 U.S. Market for Cell-based Assays, 2013-2021 ($ Millions)
  • Figure 18 European Market for Cell-Based Assays, 2013-2021 ($ Millions)
  • Figure 19 Chinese Drug Discovery Outsourcing Market, 2013-2021 ($ Millions)
  • Figure 20 Indian Drug Discovery Market, 2016 and 2021 ($ Millions)
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