美國的處方醫藥品市場

本報告已在2011年07月19日停止出版。

簡介

美國的醫藥界由於科學及技術的發展、新藥的發明、醫療知識的提高及規定的改變，可望在 2003 年的年度銷售量上，達到 2430 億美金。但是，因為醫療及藥品成本的提高、一般醫藥品的發展、專利權喪失等所帶來的競爭激烈化的影響 ，也是令人較為擔心的。

在各產業領域裡，專門從事成長市場的策略性調查的市調公司 Business Communications Company, Inc.（總公司：康乃迪克州），調查及分析美國的醫療用藥品市場，並出版綜合報告書 "U.S. Ethical Drug Market: Strategies for Sustained Growth" 。

此報告書將美國醫療界整體市場區分成醫療用（處方箋）醫藥品及 OTC 藥品兩大類，並就消費者市場、政府與管制機構、主要企業的市場佔有率及市場活動力、新區塊的參與及新搭配等進行探討 ，內容綱要如下。

前言

摘要

產業概要

• 美國的醫藥品市場
• 市場要素
• 銷售動向
• 醫藥品市場的發展要素

市場結構

• 醫療用醫藥品
• 一般醫藥品
• OTC 醫藥品

交易

• 醫藥品應用外的使用
• 認可醫藥品的新應用方式開發
• 重複專利
• 對處方箋醫藥品中的 OPC 藥品進行再分類
• 廣告＆推銷
• 流通
• 價格

醫療用醫藥品市場的課題

• 一般醫藥品企業的活動
• 違法醫藥品
• 政府的管制
• 醫藥品成本提高的影響
• 競爭狀況
• 專利權喪失
• 處方藥劑的影響
• 國家折扣程序
• 其他的優惠程序
• 從加拿大及墨西哥進口的醫藥品

持續市場成長取向的市場策略

• 製品生命週期
• 各策略對銷售額的貢獻
• 許可醫藥品的新應用方式
• 掌異構物醫藥品開發
• 複合藥
• 醫藥品應用外的使用
• 從 RX 到 OTC 醫藥品的轉變
• 對醫療用醫藥品的 OPC 藥品的再分類
• 對於專利保護/期限延長的搭配
• 醫藥品使用及評價的代價
• 詳細策略
• 廣告及推銷策略
• 附價格

主要企業檔案

• 主要處方箋醫藥品企業
• 主要生物科技醫藥品企業
• 主要一般醫藥品企業
• 對於醫療用醫藥品的 OTC 醫藥品的再分類

附錄

目錄

INTRODUCTION

STUDY GOAL AND OBJECTIVES

This report describes and discusses the strategies for sustained growth and market expansion that are being employed by participants in the U.S. prescription (ethical) drug market as the market faces various challenges. The U.S. pharmaceutical industry-driven by scientific and technological advances, new drug discoveries, advances in therapeutic knowledge and changes in government and regulatory controls-is very successful with annual sales in 2003 sales projected to reach $243 billion. However, the accelerating cost of medical care and, in particular, the escalating cost of drugs (particularly to the elderly) has the drug industry under attack. In addition, other factors are at work to limit market growth. Among these are: increasing competition (particularly from the generic drug industry), patent expirations, the impact from HMOs, hospitals and Medicaid in deciding what drugs can be prescribed and the non-compliance of patients to drug regimens.

In this report BCC provides information on the strategic market actions employed by ethical (prescription) drug companies to maintain and expand their product lines. The report also describes the pharmaceutical industry and the performance of major sectors within the industry.

Within the goals of this study, BCC will provide detailed information on the results of the various strategies and an analysis of each, with particular emphasis on how these will impact on the current and future status of the pharmaceutical market through the year 2008.

REASONS FOR DOING THE STUDY

BCC undertook this study to examine the certain factors that are at work to limit market growth in the pharmaceutical industry and the marketing strategies and tactics employed by the drug industry to extend and expand their markets.

The report provides information and analysis on:

• The ethical drug industry including description of the performance of major sectors of the total drug industry
• Increasing competition
• Patent expirations and patent extension activities
• The impact of formularies in deciding which drugs are prescribed
• Strategic market actions employed by pharmaceutical companies to expand their market segments
• Product expanded applications
• Life cycle management
• Prescription to OTC switches and branded generics
• "Off-label" use of drugs
• Advertising strategies, including pre-approval advertising and direct to consumer (DTC) advertising
• Internet detailing
• Mail order marketing
• Pricing practices

CONTRIBUTIONS OF THE STUDY AND FOR WHOM

This report should prove of particular value to both pharmaceutical marketing participants and observers, as well as to investors and venture capitalists, since it provides details on the United States pharmaceutical market. Such details include data on market size by major sector structure and dynamics of the industry, expansion and changes in traditional market strategies, and new marketing concepts and trends.

SCOPE AND FORMAT

In preparation of this report, the entire pharmaceutical industry was examined, with particular emphasis on those drug companies that are employing innovative marketing strategies to be the market leaders of the next century.

The U.S. drug industry is segmented into ethical (prescription) and over-the-counter drugs in both the branded and generic forms. This report attempts to discuss all areas of the market and to identify significant suppliers, end markets and government and regulatory agencies. Participating companies will be discussed regarding relative market share, marketing strengths, participation in new segments and innovative marketing practices.

METHODOLOGY

Data for this study were collected using both primary and secondary data research techniques. A literature search of BCC's extensive library, as well as pharmaceutical, medical and business libraries was conducted. Extensive interviews with industry personnel, professional and trade organizations, government agency personnel, observers, scientists and industry professionals were conducted.

Data collected were analyzed by BCC personnel to determine specific findings and forecasts. Once these forecasts were obtained they were validated with industry experts; consequently, all estimates provided in this report represent a consensus of BCC personnel, industry participants and industry observers. Since some segments of this report are not routinely measured, BCC derived estimates from a variety of analogous sources. Whenever market estimates are derived they are fully noted. All dollar amounts are expressed in constant 2003 U.S. dollars.

INFORMATION SOURCES

Information contained in this report includes data obtained from government agencies, corporate publications and findings from industry trade associations. Other information sources were interviews with industry personnel, corporations, government and professional agencies and trade associations. Further information was obtained through our extensive literature search.

TABLE OF CONTENTS

INTRODUCTION

• STUDY GOAL AND OBJECTIVES
• REASONS FOR DOING THE STUDY
• CONTRIBUTIONS OF THE STUDY AND FOR WHOM
• SCOPE AND FORMAT
• METHODOLOGY
• INFORMATION SOURCES
• AUTHOR'S CREDENTIALS
• RELATED BCC WORK CREDENTIALS
• BCC ON-LINE SERVICES
  • INTERNET

SUMMARY

• REPORT HIGHLIGHTS
• Summary Table:
  THE U.S. DRUG MARKET AND REVENUE CONTRIBUTIONS FROM EMERGING AND UPDATED STRATEGIC, THROUGH 2008 ($ BILLIONS)
• Summary Figure:
  PERCENTAGE SHARE OF EMERGING MARKETING STRATEGIES, 2003 AND 2008 (%)

OVERVIEW

• THE U.S. DRUG MARKET
• MARKET COMPONENTS
• SALES TRENDS
  • SALES TRENDS (CONTINUED)
• Figure 1 TRENDS IN ETHICAL, GENERIC AND OTC PHARMACEUTICAL DRUG SALES, 2003-2008 ($ BILLIONS)
  • DRIVING FORCES OF THE DRUG MARKET
    • SCIENTIFIC ADVANCES
    • Biotechnology Drugs
    • Recombinant DNA Technology
    • Hybridoma Cell Technology
    • Steps Involved in Producing Biotechnology Drugs
    • Transgenic Animals for Protein Drug Production
    • Microorganism or Hybridoma Production
    • Recently Developed Biotechnology Drugs
• Table 1 SELECTED LISTING OF RECENTLY DEVELOPED BIOTECHNOLOGY DRUGS
  • MARKET DEMAND
  • Aging Population
  • DRUG DEVELOPMENT TIME
  • FDA Actions to Reduce Drug Approval Time
  • PATENTS
• Figure 2 WORLDWIDE POPULATION PROFILE, RELATIVE PERCENTAGES, 2003 AND 2008 (%)

MARKET STRUCTURE

• Figure 3 RELATIVE SHARE U.S. DOMESTIC PHARMACEUTICAL MARKET, 2003 AND 2008 ($ BILLIONS)
• Figure 3 (CONTINUED)
  • ETHICAL DRUGS
• Table 2 AVERAGE NUMBER OF DETAILING VISITS WITH PHYSICIANS PER YEAR, 1996-2003
  • SUSTAINING GROWTH THROUGH R&D
• Figure 4 R&D EXPENDITURES LEADING PHARMACEUTICAL COMPANIES, 2002 ($ BILLIONS)
  • ETHICAL DRUG APPLICATION APPROVALS
  • Fast Track Approval
• Table 3 ETHICAL DRUG APPROVALS THROUGH NOVEMBER 2003
• Table 3 (CONTINUED)
  • GENERIC DRUGS
• Table 4 U.S. PRESCRIPTION DRUGS SALES, 2003
  • GENERIC DRUG APPROVAL PROCESS
  • BRANDED GENERICS
  • Exploiting 505(b)(2)
• Table 5 BRANDED GENERIC DRUG U.S. SALES, THROUGH 2008 ($ BILLIONS)
  • OVER-THE-COUNTER DRUGS (OTC)
    • OTC DRUGS COVERED BY HEALTH CARE FLEXIBLE SPENDING ACCOUNTS
    • OTC Drugs Covered by Health Care Flexible Spending Accounts (Continued)

TRADE PRACTICES

• OFF-LABEL USE OF DRUGS
• DEVELOPING NEW INDICATIONS FOR ALREADY APPROVED DRUGS
• RECLASSIFICATION OF PRESCRIPTION DRUGS TO OVER-THE-COUNTER (OTC) STATUS
• OVER-LAPPING PATENTS
• ADVERTISING & PROMOTION
• DISTRIBUTION METHODS
• PRICING
  • PRESCRIPTION ACCESS LITIGATION (PAL)
  • Prescription Access Litigation (Continued)

CHALLENGES TO ETHICAL DRUG MARKET

• ACTIONS OF GENERIC DRUG COMPANIES
• COUNTERFEIT DRUGS
  • POTENTIAL ANTI-COUNTERFEITING REGULATIONS
• GOVERNMENT REGULATIONS
  • HATCH-WAXMAN ACT
  • OFFICE OF THE INSPECTOR GENERAL (OIG)
  • STATE LIMITS FOR MEDICAID PRESCRIBING
  • PROPOSED MEDICARE PRESCRIPTION BENEFITS
• IMPACT OF INCREASING COST OF DRUGS
• Table 6 AVERAGE ANNUAL RATE INCREASE IN PRESCRIPTION DRUG EXPENDITURES (%)
  • INCREASED COST TO THE ELDERLY
  • INCREASES IN CO-PAYMENTS
  • COMPETITION
  • PATENT EXPIRATIONS
    • CURRENT PATENT EXPIRATION STATUS
• Table 7 TOP SELLING DRUGS WITH PATENT EXPIRATION BETWEEN 2003 AND 2008
• Table 7 (CONTINUED)
  • IMPACT OF FORMULARIES
  • STATE DISCOUNT PROGRAMS
  • OTHER PHARMACEUTICAL BENEFITS PROGRAMS
  • IMPORTATION OF DRUGS FROM CANADA AND MEXICO
    • CANADIAN INTERNET RX SALES TO U.S. PROJECTED TO GROW
• Table 8 COMPARISON OF U.S. AND CANADIAN PRICES FOR SELECTED PRESCRIPTION DRUGS ($ U.S.)
  • DRUGS FROM MEXICO

MARKETING STRATEGIES FOR SUSTAINED GROWTH

• PRODUCT LIFE CYCLES
• REVENUE CONTRIBUTION FROM EACH STRATEGY
• Table 9 REVENUE CONTRIBUTION TO U.S. DRUG SLAES FROM MARKETING STRATEGIES FOR SUSTAINED GROWTH, THROUGH 2008
• Figure 5 REVENUE CONTRIBUTION FROM MARKETING STRATEGIES FOR SUSTAINED GROWTH, 2003 AND 2008 (%)
• Figure 5 (CONTINUED)
  • NEW INDICATIONS FOR APPROVED DRUGS
    • CONTINUING TESTING AFTER A NEW DRUG IS APPROVED
    • RECENTLY APPROVED NEW DRUG INDICATIONS
• Table 10 RECENT NEW DRUG INDICATIONS, 2003
  • CHIRAL DRUG DEVELOPMENT
• Table 11 REVENUE CONTRIBUTION FROM CHIRAL DRUG DEVELOPMENT, THROUGH 2008 ($ BILLIONS)
  • RECENT EXAMPLES OF RACEMATIC PRODUCT LIFE EXTENSIONS
  • IMPROVED CHEMICAL ENTITIES (ICES)
  • COMBINATION DRUGS
• Table 12 REVENUE CONTRIBUTION FROM COMBINATION DRUG DEVELOPMENT, THROUGH 2008 ($ MILLIONS)
  • OFF-LABEL DRUG USE
    • MOVEMENT TOWARD OFF-LABEL USE
• Table 13 ESTIMATED PERCENTAGE OF OFF-LABEL DRUG USE BY PATIENT TYPE (%)
• Table 14 REVENUE CONTRIBUTION FROM OFF-LABEL DRUG USE, THROUGH 2008 ($ BILLIONS)
  • MEASURING PATIENT-REPORTED OUTCOMES (PROS)
  • MEDICAID REIMBURSEMENT STANDARDS FOR OFF-LABEL DRUG USE
  • OTHER PUBLICATIONS FOR OFF-LABEL DRUG USE
  • ARGUMENTS AGAINST OFF-LABEL DRUG USE
  • Fenfluramine and Phentermine (Fen-Phen)
  • Encainide and Flecainide
  • RX TO OTC SWITCHES
• Table 15 REVENUE CONTRIBUTION FROM RX TO OTC SWITCHES, THROUGH 2008 ($ BILLIONS)
  • RECLASSIFICATION OF ETHICAL DRUGS TO OTC
• Table 16 PERCENTAGE OF U.S. DRUG SALES FROM RX TO OTC SWITCHES (%)
  • RECENTLY APPROVED RX TO OTC SWITCHED DRUGS
• Figure 6 NUMBER OF RECENTLY APPROVED RX TO OTC SWITCHES
  • RX TO OTC APPROVAL
  • DRUGS SUCCESSFULLY SWITCHED
• Table 17 SELECTED LIST OF PHARMACEUTICAL DRUGS SUCCESSFULLY SWITCHED TO OTC STATUS
  • THIRD PARTIES PETITIONING FDA FOR RX TO OTC SWITCHES
  • Challenge from National Consumers League
  • Probable Future Switches
  • Emergency Contraception Drugs
  • Plan B
  • Preven
  • Asthma Treatments
  • PATENT PROTECTION/EXTENSION EFFORTS
• Table 18 2008 SALES PROJECTIONS FOR DRUGS WITH PATENT EXPIRATION BETWEEN 2003 AND 2008 ($ MILLIONS)
• Table 19 REVENUE CONTRIBUTION FROM MULTIPLE PATENT/EXTENSION EFFORTS, THROUGH 2008 ($ BILLIONS)
  • FILING MULTIPLE PATENT APPPLICATIONS FOR SAME DRUG
• Table 20 SELECTED LIST OF PATENTS EXPIRATIONS*
• Table 21 MULTIPLE PATENT ANALYSIS-SELECTED BLOCKBUSTER DRUGS
  • LEGAL MANUEVERING TO PREVENT GENERIC COMPETITION
  • Patent Infringement Suits Under Attack
  • Multiple Patent Protection Strategy Challenged
  • ENTERING INTO MARKETING ALLIANCES
  • PAYING FOR DRUG USE/EVALUATION
• Table 22 ANNUAL EXPENDITURES BY PHARMACEUTICAL COMPANIES FOR PAYMENT INCENTIVES TO DOCTORS, THROUGH 2008 ($ BILLIONS)
  • ESTIMATED VALUE OF PAYMENT INCENTIVES TO DOCTORS
• Table 23 REVENUE FROM PAYMENT INCENTIVES TO DOCTORS, THROUGH 2008 ($ BILLIONS)
  • EFFORTS TO LIMIT PAYMENTS AND GIFTS
  • PROVIDING DOCTORS WITH DISCOUNTS FOR DRUGS
  • DRUG REBATES
  • TACTICS TO BOOST OFF-LABEL USE
  • ADVERTISING AND PROMOTION STRATEGIES
• Table 24 PROMOTIONAL EXPENDITURES FOR ETHICAL DRUGS MARKETING, THROUGH 2008 ($ BILLIONS)
  • DIRECT TO CONSUMER ADVERTISING
  • Volume of Direct-to-Consumer Advertising
• Table 25 TRENDS IN DTC ADVERTISING EXPENDITURES, THROUGH 2008 ($ BILLIONS)
  • Revenue Contribution from DTC Advertising
• Table 26 ESTIMATED REVENUE CONTRIBUTION FROM DTC ADVERTISING, THROUGH 2008 ($ BILLIONS)
  • FDA DTC Guidelines
  • PRE-APPROVAL ADVERTISING
  • DETAILING STRATEGIES
    • ELECTRONIC (INTERNET) DETAILING
• Table 27 SELECTED LISTING OF PHARMACEUTICAL COMPANIES USING e-DETAILING
  • Suppliers of e-detailing Services
  • RxCentric Incorporated
  • PharmiWeb
  • Lathian Systems Incorporated
  • Revenue Contribution of E-Detailing
  • BLITZ DETAILING
  • PRICING PRACTICES
    • OIG COMPLIANCE PROGRAM GUIDANCE
    • OIG Compliance Program Guidance (Continued)
    • Revenue Contribution from Pricing Strategies

PROFILES OF LEADING COMPANIES

• Table 28 STRATEGIES FOR SUSTAINED GROWTH USED BY TOP TEN U.S. ETHICAL DRUG COMPANIES
  • LEADING PRESCRIPTION DRUG COMPANIES
• Table 29 PHARMACEUTICAL SALES VOLUME TOP TEN COMPANIES, 2002 ($ BILLIONS)
• Table 30 TOP TEN PHARMACEUTICL COMPANIES SALES AS PERCENTAGE OF WORLDWIDE SALES, 2002
• Figure 7 TOP TEN PHARMACEUTICL COMPANIES SALES AS PERCENTAGE OF WORLDWIDE SALES, 2002
  • PFIZER INC.
• Table 31 PFIZER'S MAJOR DRUGS
  • Pfizer Inc. (Continued)
  • GLAXOSMITHKLINE
• Table 32 SELECTED LISTING GLAXOSMITHKLINE CONSUMER HEALTH PRODUCTS
  • MERCK & COMPANY, INC.
• Table 33 MERCK REVENUE BY THERAPEUTIC SEGMENT, 2002 ($ BILLIONS)
  • ASTRAZENECA PLC
  • AstraZeneca Pharmaceuticals LP
• Table 34 MAJOR PRODUCTS, ASTRAZENECA
  • AVENTIS SA
  • Aventis Pharmaceuticals Inc.
  • JOHNSON & JOHNSON
  • Johnson & Johnson (Continued)
• Table 35 J&J's LEADING DRUGS
  • ALZA CORPORATION
  • ORTHO-MCNEIL
• Table 36 ORTHO-MCNEIL SELECTED PRODUCT LISTING
  • CENTOCOR, INC.
  • JANSSEN PHARMACEUTICALS
  • NOVARTIS INTERNATIONAL AG
  • Novartis Corporation
• Table 37 NOVARTIS' LEADING PRODUCTS
  • BRISTOL-MYERS SQUIBB COMPANY
  • WYETH
• Table 38 WYETH'S LEADING PRODUCTS
  • ELI LILLY AND COMPANY
  • LEADING BIOTECHNOLOGY DRUG COMPANIES
    • AMGEN INC.
• Table 39 AMGEN'S PRODUCT LINE
  • GENENTECH, INC.
  • Oncology
  • Immunological Disease
  • Vascular Medicine
  • SERONO INTERNATIONAL S.A.
  • Serono, Inc.
  • CHIRON
  • LEADING GENERIC DRUG COMPANIES
    • MYLAN LABORATORIES INCORPORATED
    • BARR LABORATORIES
    • ALPHARMA INCORPORATED
    • PHARMACEUTICAL RESOURCES
    • DR. REDDY'S LABORATORIES LIMITED

APPENDIX

• RECENT GENERIC DRUG APPROVALS
  • RECENT GENERIC DRUG APPROVALS (CONTINUED)
  • RECENT GENERIC DRUG APPROVALS (CONTINUED)
  • RECENT GENERIC DRUG APPROVALS (CONTINUED)
  • RECENT GENERIC DRUG APPROVALS (CONTINUED)
  • RECENT GENERIC DRUG APPROVALS (CONTINUED)
  • RECENT GENERIC DRUG APPROVALS (CONTINUED)

LIST OF TABLES

Summary Table:
THE U.S. DRUG MARKET AND REVENUE CONTRIBUTIONS FROM EMERGING AND UPDATED STRATEGIC, THROUGH 2008 ($ BILLIONS)

Table 1 SELECTED LISTING OF RECENTLY DEVELOPED BIOTECHNOLOGY DRUGS

Table 2 AVERAGE NUMBER OF DETAILING VISITS WITH PHYSICIANS PER YEAR, 1996-2003

Table 3 ETHICAL DRUG APPROVALS THROUGH NOVEMBER 2003

Table 4 U.S. PRESCRIPTION DRUGS SALES, 2003

Table 5 BRANDED GENERIC DRUG U.S. SALES, THROUGH 2008 ($ BILLIONS)

Table 6 AVERAGE ANNUAL RATE INCREASE IN PRESCRIPTION DRUG EXPENDITURES (%)

Table 7 TOP SELLING DRUGS WITH PATENT EXPIRATION BETWEEN 2003 AND 2008

Table 8 COMPARISON OF U.S. AND CANADIAN PRICES FOR SELECTED PRESCRIPTION DRUGS ($ U.S.)

Table 9 REVENUE CONTRIBUTION TO U.S. DRUG SLAES FROM MARKETING STRATEGIES FOR SUSTAINED GROWTH, THROUGH 2008

Table 10 RECENT NEW DRUG INDICATIONS, 2003

Table 11 REVENUE CONTRIBUTION FROM CHIRAL DRUG DEVELOPMENT, THROUGH 2008 ($ BILLIONS)

Table 12 REVENUE CONTRIBUTION FROM COMBINATION DRUG DEVELOPMENT, THROUGH 2008 ($ MILLIONS)

Table 13 ESTIMATED PERCENTAGE OF OFF-LABEL DRUG USE BY PATIENT TYPE (%)

Table 14 REVENUE CONTRIBUTION FROM OFF-LABEL DRUG USE, THROUGH 2008 ($ BILLIONS)

Table 15 REVENUE CONTRIBUTION FROM RX TO OTC SWITCHES, THROUGH 2008 ($ BILLIONS)

Table 16 PERCENTAGE OF U.S. DRUG SALES FROM RX TO OTC SWITCHES (%)

Table 17 SELECTED LIST OF PHARMACEUTICAL DRUGS SUCCESSFULLY SWITCHED TO OTC STATUS

Table 18 2008 SALES PROJECTIONS FOR DRUGS WITH PATENT EXPIRATION BETWEEN 2003 AND 2008 ($ MILLIONS)

Table 19 REVENUE CONTRIBUTION FROM MULTIPLE PATENT/EXTENSION EFFORTS, THROUGH 2008 ($ BILLIONS)

Table 20 SELECTED LIST OF PATENTS EXPIRATIONS*

Table 21 MULTIPLE PATENT ANALYSIS-SELECTED BLOCKBUSTER DRUGS

Table 22 ANNUAL EXPENDITURES BY PHARMACEUTICAL COMPANIES FOR PAYMENT INCENTIVES TO DOCTORS, THROUGH 2008 ($ BILLIONS)

Table 23 REVENUE FROM PAYMENT INCENTIVES TO DOCTORS, THROUGH 2008 ($ BILLIONS)

Table 24 PROMOTIONAL EXPENDITURES FOR ETHICAL DRUGS MARKETING, THROUGH 2008 ($ BILLIONS)

Table 25 TRENDS IN DTC ADVERTISING EXPENDITURES, THROUGH 2008 ($ BILLIONS)

Table 26 ESTIMATED REVENUE CONTRIBUTION FROM DTC ADVERTISING, THROUGH 2008 ($ BILLIONS)

Table 27 SELECTED LISTING OF PHARMACEUTICAL COMPANIES USING e-DETAILING

Table 28 STRATEGIES FOR SUSTAINED GROWTH USED BY TOP TEN U.S. ETHICAL DRUG COMPANIES

Table 29 PHARMACEUTICAL SALES VOLUME TOP TEN COMPANIES, 2002 ($ BILLIONS)

Table 30 TOP TEN PHARMACEUTICL COMPANIES SALES AS PERCENTAGE OF WORLDWIDE SALES, 2002

Table 31 PFIZER'S MAJOR DRUGS

Table 32 SELECTED LISTING GLAXOSMITHKLINE CONSUMER HEALTH PRODUCTS

Table 33 MERCK REVENUE BY THERAPEUTIC SEGMENT, 2002 ($ BILLIONS)

Table 34 MAJOR PRODUCTS, ASTRAZENECA

Table 35 J&J's LEADING DRUGS

Table 36 ORTHO-MCNEIL SELECTED PRODUCT LISTING

Table 37 NOVARTIS' LEADING PRODUCTS

Table 38 WYETH'S LEADING PRODUCTS

Table 39 AMGEN'S PRODUCT LINE  

LIST OF FIGURES

Summary Figure:
PERCENTAGE SHARE OF EMERGING MARKETING STRATEGIES, 2003 AND 2008 (%)

Figure 1 TRENDS IN ETHICAL, GENERIC AND OTC PHARMACEUTICAL DRUG SALES, 2003-2008 ($ BILLIONS)

Figure 2 WORLDWIDE POPULATION PROFILE, RELATIVE PERCENTAGES, 2003 AND 2008 (%)

Figure 3 RELATIVE SHARE U.S. DOMESTIC PHARMACEUTICAL MARKET, 2003 AND 2008 ($ BILLIONS)

Figure 4 R&D EXPENDITURES LEADING PHARMACEUTICAL COMPANIES, 2002 ($ BILLIONS)

Figure 5 REVENUE CONTRIBUTION FROM MARKETING STRATEGIES FOR SUSTAINED GROWTH, 2003 AND 2008 (%)

Figure 6 NUMBER OF RECENTLY APPROVED RX TO OTC SWITCHES

Figure 7 TOP TEN PHARMACEUTICL COMPANIES SALES AS PERCENTAGE OF WORLDWIDE SALES, 2002

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