全球細胞・組織分析產品市場 是由出版商BCC Research在2009年09月所出版的。
這份英文市場調查報告書包含183 pages 價格從美金4850起跳。
本報告書內容包括：全球細胞・組織分析產品市場綜合分析、用途別市場分類及2014年之前的市場預測、主要銷售企業及M&A、政府的法規限制動向、產業整體動向等。內容綱要摘記如下：
第1章 介紹
第2章 摘要
第3章 概要
第4章 產業結構及競爭分析
- 進入產業的企業
- 組織微陣列
- 細胞分離產品
- 研究用抗體
- 細胞基礎試驗
- 高度內容篩選（HCS）產品
- 生物測試材料（Biospecimens）
- 雷射顯微切割（LMD）
- 流體細胞技術
- 研究用抗體
- HCS/細胞基礎試驗
- M&A・策略聯盟・夥伴關係
- 生物測試材料
- LMD
- 流體細胞技術
- 研究用抗體
- HCS
第5章 細胞・組織分析技術
- 介紹
- 生物測試材料技術
- 細胞分離技術
- 細胞・組織分析技術
第6章 專利環境
- 介紹
- 細胞・組織分析產業
- 生物測試材料銷售企業用專利
- 細胞分離產品企業用專利
- 細胞・組織分析企業用專利
- 研究用抗體的專利
- HCS的專利
- 細胞基礎試驗的專利
第7章 最終使用者
- 介紹
- 學術研究機構
- 生物藥品製造業者
- 醫療・臨床
- 全球情勢
- 全球市場
- 產品別市場
- 地區別市場
第8章 企業介紹
Abstract
THIS REPORT:
- Provides a comprehensive overview of the global market for cell and tissue
analysis products
- Offers a breakdown of the market by application including those for
diagnostics, basic research, drug screening and others
- Contains global market forecasts for cell and tissue analysis products,
with trends and forecasts for growth through 2014
- Discusses industry structure including key vendors, mergers and
acquisitions, distribution of products, government regulation and industry
trends
- Describes the latest technological advances including those in flow
cytometry, microscope based image analysis, high throughput screening (HTS)
devices and reagents and supplies.
INTRODUCTION
STUDY GOALS AND OBJECTIVES
This BCC Research report, Cell and Tissue Analysis Products: The Global
Market, provides a detailed analysis of the products and technologies that
define the market space and summarizes the composition and dynamics of
individual companies in the competitive environment. The study also includes
an overview of the relevant regulatory issues, patent landscapes, and
strategic partnerships that will play a role in shaping the market in the
future.
REASONS FOR DOING THE STUDY
The use of cells and tissue has been a mainstay of biomedical research since
the isolation and propagation of the HeLa cell in the 1950s. Along with the
recent emphasis on translational research in academia and demand for improved
clinical models during drug development and screening, the current use of
tissue and cells in the life sciences is at an all time high, creating intense
demand for upstream isolation and downstream analytical products in industrial
and academic markets.
Contemporary tissue repositories have vastly expanded their capacity and stock
breadth. Technological advances in cellular engineering now have the ability
to produce customized cell lines for specific research and industrial
applications. In parallel, the cell remains at the center of experimental
design in academia. All of these factors, as well as numerous others, have led
to increased demand for products used to isolate and analyze cells and tissue.
The recent surge in NIH and NSF funding, $10.4 billion and $3 billion,
respectively, stemming from President Obama' s stimulus package, will serve to
drive novel and existing domestic research programs. As innovative projects
get underway and new proposals are developed, the acute demand for products
associated with life-science research will increase accordingly. As a
corollary, due to the central role of cell and tissue analysis products in the
life-science research flow, this market report will be particularly timely.
SCOPE OF REPORT
The study scope of this report includes commercialized products used in the
isolation, purification, and analysis of cells, as well as novel products and
technologies that may be commercially viable by 2014. Biospecimens, enzymatic,
and mechanical tissue dissociation products, flow cytometry hardware and
software, magnetic cell separation products, laser microdissection (LMD)
systems, research antibodies, cell based assays and products used in high
content screening (HCS) platforms are included. Market growth forecasts
through 2014 are presented.
In addition to examining larger and more established producers in cell and
tissue analysis product market segments, BCC Research profiled numerous
smaller specialized market players in this report. Market segmentation within
the areas of biospecimen vendors, cell separation products and cell and tissue
analysis products are highlighted. Each technology is also analyzed by
application type and in the context of relevant technological and regulatory
forces to determine its current market status and forecast growth through
2014. Recent industrial alliances and acquisitions affecting producer market
penetration and dominance are also discussed.
BCC examines the structure of both the academic research and industrial
end-user markets predominantly in the U.S., but also in key international
markets. Important intellectual property holdings of industrial producers of
cell and tissue analysis products are also discussed.
INTENDED AUDIENCE
This report will be of general interest to business professionals in the field
of biotechnology. Both life science reagent suppliers and research scientists
will benefit from the comprehensive summary of relevant technologies and
industrial profiles contained here. Consultants, strategic and market
analysts, and investors working within the pharmaceutical, clinical and
biotechnology industries will also find this report particularly useful. In
addition, business development professionals, as well as those in sales,
marketing, information sciences, and competitive intelligence fields of
biotechnology will benefit from the information contained in this report.
METHODOLOGY AND INFORMATION SOURCES
The market assessments presented in this report were derived from publicly
available information up to and including April 2009. Using 2008 as the base
year, forecast data are provided through 2014. In cases where data for 2009
were incomplete or not readily available, figures were extrapolated from 2008
statistics, half-year figures for 2008, and historical trends between 2004 and
2008. Market figures are based on current U.S. dollars with no adjustments for
inflation made in the projections.
The information contained in this report has been assembled from both primary
and secondary data sources. Primary research was conducted via telephone
interviews with industry professionals, research scientists,
physician-researchers, and laboratory heads to discover the most recent
developments in their fields of interest. Secondary data was collected via a
comprehensive search of the scientific, peer-reviewed literature, clinical
trial reports and databases, industry trade media, company websites, annual
reports, intellectual property databases, and industry press releases.
Table of Contents
Chapter- 1: INTRODUCTION -- Complimentary 4
- STUDY GOALS AND OBJECTIVES 1
- REASONS FOR DOING THE STUDY 1
- SCOPE OF REPORT 1
- INTENDED AUDIENCE 2
- METHODOLOGY AND INFORMATION SOURCES 2
- ANALYST CREDENTIALS 3
- RELATED BCC REPORTS 3
- BCC ONLINE SERVICES 3
- DISCLAIMER 4
Chapter-2: SUMMARY 2NERAL DESCRIPTION 7
- DEFINITIONS 7
- Antibody 8
- Antigen 8
- Apoptosis 8
- Biomarker 8
- Biospecimen 8
- Cell 9
- TABLE 1 CHARACTERISTICS OF PROKARYOTIC AND EUKARYOTIC CELLS 9
- TABLE 2 CHARACTERISTICS OF PLANT AND ANIMAL CELLS 9
- TABLE 2 (CONTINUED) 10
- Cell-Based Assay 10
- Epitope 10
- Flow Cytometer 10
- FIGURE 1 MAIN COMPONENTS OF A FLOW CYTOMETER 11
- Fluorescence Activated Cell Sorting 12
- High-Content Screening 12
- Hybridoma 12
- Immunohistochemistry 12
- In vitro Culture 13
- Isotype 13
- Laser Microdissection 13
- Monoclonal (Antibody) 14
- Polyclonal (Antibody) 14
- Primary Antibody 14
- Primary Cells 14
- Secondary Antibody 14
- Tissue 15
- TABLE 3 MAJOR TISSUE TYPES AND CONSTITUENT CELLS 15
- Tissue Microarray 15
- INDUSTRY DEFINITION 16
- INDUSTRY BREAKDOWN 16
- Biospecimens 16
- TABLE 4 MAJOR BIOSPECIMENS USED IN RESEARCH AND DRUG DEVELOPMENT 17
- TABLE 5 BIOSPECIMENS LIFECYCLE 17
- Cell and Tissue Separation Products 18
- TABLE 6 MAJOR TYPES OF CELL AND TISSUE SEPARATION PRODUCTS USED IN
RESEARCH AND DRUG DEVELOPMENT 18
- Cell and Tissue Characterization Products 18
- TABLE 7 APPLICATIONS OF CELL AND TISSUE CHARACTERIZATION PRODUCTS IN
RESEARCH AND DRUG DEVELOPMENT 19
- PRODUCT BREAKDOWN 19
- Biospecimens 19
- History 19
- Types of Biospecimens 19
- Tissue Microarray 20
- History 20
- Frozen Arrays 20
- FFPE Arrays 21
- TMA Applications 21
- Cell and Tissue Dissociation 22
- Enzymatic Dissociators 22
- TABLE 8 COMMON ENZYMES USED FOR CELL AND TISSUE DISSOCIATION 22
- Mechanical Dissociators 22
- Bead Method 23
- Sonication 23
- Pressure Homogenizing 23
- Rotor-stator Homogenizing 23
- Manual Grinding 24
- Blade Homogenizing 24
- Magnetic Cell Separation Technology 24
- Technology 24
- Laser Microdissection 25
- History 25
- LMD Applications 25
- LMD Platforms 26
- Laser Microdissection and Pressure Catapulting 26
- Fusion Microdissection 26
- Flow Cytometry 26
- History 26
- Cytometer Types 27
- Analyzers 27
- Sorters 27
- Detection 27
- Clinical Applications 28
- Research Applications 28
- Research Antibodies 28
- History 28
- Antibody Types 29
- Primary Antibodies 29
- Secondary Antibodies 29
- Isotype Controls 30
- Antibody Specifications 30
- Host 30
- TABLE 9 HOST SPECIES USED IN GENERATING RESEARCH ANTIBODIES (SPECIES) 30
- Class/Isotype 30
- Target Species (Reactivity) 31
- Label 31
- TABLE 10 COMMON ANTIBODY LABELS (TYPE) 31
- Cell-Based Assays 31
- History 31
- Applications of Cell-Based Assays 32
- Types of Cell-Based Assays 32
- Signaling Assays 32
- Cell Viability/Death Assays 32
- Cell Proliferation Assays 33
- Cell Migration Assays 33
- High-Content Screening 34
- History 34
- HCS Applications 34
- HCS Instrumentation 35
- Confocal Machines 35
- Non-confocal Machines 35
- REGULATORY ISSUES 35
- HISTORY 35
- Biomedical Tissue Services 36
- American Tissue 37
- Willed Body Program 37
- Body World 37
- Bodies...the Exhibition 38
- BIOSPECIMEN REGULATORY STRUCTURE 38
- Federal Regulations 38
- Current Good Tissue Practices 38
- TABLE 11 INTERNATIONAL REGULATORY RULES & RULINGS GUIDING THE ACCESS/USE
OF HUMAN TISSUE IN RESEARCH AND DRUG DISCOVERY, 2001 - 2009 39
- State Regulations 39
Chapter-3: OVERVIEW 33
Chapter-4: INDUSTRY STRUCTURE AND COMPETITIVE ANALYSIS 19
- INDUSTRY PARTICIPANTS 40
- TISSUE MICROARRAYS 40
- TABLE 12 MAJOR COMPANIES IN THE TISSUE MICROARRAY MARKET 40
- TABLE12 (CONTINUED) 41
- CELL SEPARATION PRODUCTS 41
- TABLE 13 MAJOR COMPANIES IN THE CELL SEPARATION PRODUCT MARKET 41
- TABLE 13 (CONTINUED) 42
- RESEARCH ANTIBODIES 42
- TABLE 14 MAJOR COMPANIES IN THE RESEARCH ANTIBODIES MARKET 43
- TABLE 15 COMPANIES IN THE GMP ANTIBODY PRODUCTION MARKET 43
- TABLE 15 (CONTINUED) 44
- TABLE 15 (CONTINUED) 45
- TABLE 16 COMPANIES IN THE GMP ANTIBODY PRODUCTION MARKET, BY LOCATION,
2009 45
- TABLE 16 (CONTINUED) 46
- CELL-BASED ASSAYS 46
- TABLE 17 COMPANIES IN THE CELL-BASED ASSAY PRODUCT MARKET 47
- HIGH-CONTENT SCREENING PRODUCTS 47
- TABLE 18 COMPANIES IN THE HIGH CONTENT SCREENING INSTRUMENTATION PRODUCT
MARKET 48
- MARKET SHARES 48
- BIOSPECIMENS 48
- TABLE 19 MARKET SHARE OF COMMERCIAL BIOSPECIMEN VENDORS 2008 ($ MILLION,
%) 48
- LASER MICRODISSECTION 49
- TABLE 20 MARKET SHARE OF COMMERCIAL LASER MICRODISSECTION MARKET LEADERS
2009 ($ MILLION, %) 49
- FLOW CYTOMETRY 50
- TABLE 21 MARKET SHARE OF COMMERCIAL FLOW CYTOMETRY MARKET LEADERS, 2008 ($
MILLIONS) 50
- RESEARCH ANTIBODIES 50
- TABLE 22 MARKET SHARE OF COMMERCIAL RESEARCH ANTIBODY MARKET LEADERS, 2008
($ MILLIONS) 51
- HIGH CONTENT SCREENING/CELL-BASED ASSAYS 51
- TABLE 23 MARKET SHARE OF COMMERCIAL HIGH CONTENT SCREENING AND CELL-BASED
ASSAY INSTRUMENTATION MARKET LEADERS, 2009 ($ MILLIONS) 52
- TABLE 24 MARKET SHARE OF COMMERCIAL HIGH CONTENT SCREENING AND CELL-BASED
ASSAY REAGENT MARKET LEADERS, 2009 ($ MILLIONS) 52
- MERGERS, ACQUISITIONS, STRATEGIC ALLIANCES & PARTNERSHIPS 53
- BIOSPECIMENS 53
- TABLE 25 MAJOR BIOSPECIMEN INDUSTRY EVENTS, 2005 - 2009 53
- LASER MICRODISSECTION 54
- TABLE 26 MAJOR LASER MICRODISSECTION INDUSTRY EVENTS, 2004 - 2009 54
- FLOW CYTOMETRY 55
- TABLE 27 MAJOR FLOW CYTOMETRY INDUSTRY EVENTS, 2005 - 2009 55
- RESEARCH ANTIBODIES 55
- TABLE 28 MAJOR RESEARCH ANTIBODY INDUSTRY EVENTS, 2005 - 2009 56
- Notable Developments 57
- HIGH CONTENT SCREENING 57
- TABLE 29 MAJOR HIGH CONTENT SCREENING INDUSTRY EVENTS, 2004 - 2009 57
- TABLE 29 (CONTINUED) 58
Chapter-5: CELL AND TISSUE ANALYSIS TECHNOLOGIES 36
- INTRODUCTION 59
- BIOSPECIMEN TECHNOLOGIES 59
- TABLE 30 NEW PRODUCTS FROM BIOSPECIMEN MARKET COMPANIES 59
- TABLE 30 (CONTINUED) 60
- TABLE 30 (CONTINUED) 61
- TISSUE MICROARRAYS 61
- TABLE 31 PRODUCT SPECIFICATIONS OF TISSUE MICROARRAYS 62
- FIGURE 2 FLOW DIAGRAM FOR TISSUE MICROARRAY PRODUCTION 63
- Tissue Microarray Production 64
- Types of Tissue Microarrays 64
- Frozen Tissue Arrays 64
- FFPE Arrays 65
- TABLE 32 COMPARISON OF THE MAIN TYPES OF TISSUE MICROARRAY FORMATS 66
- Multi-sample Arrays 66
- Progression Arrays 67
- Prognosis Arrays 67
- Applications of TMA 67
- TABLE 33 EXAMPLE APPLICATIONS OF DIFFERENT TISSUE MICROARRAY PREPARATIONS
67
- TABLE 33 (CONTINUED) 68
- TABLE 34 COMMMON DISEASED TISSUES AVAILABLE IN TISSUE MICROARRAY FORMAT 68
- TABLE 34 (CONTINUED) 69
- New Developments in Tissue Microarray Technology 69
- TABLE 35 TISSUE MICROARRAY, TECHNOLOGY DEVELOPMENT 70
- Matrix Assembly 71
- TMA Content 71
- TMA Analysis Software 72
- TABLE 36 COMPARISON OF TISSUE MICROARRAY ANALYSIS SOFTWARE PACKAGES 73
- TABLE 36 (CONTINUED) 74
- CELL SEPARATION TECHNOLOGIES 75
- MECHANICAL AND ENZYMATIC SEPARATION 75
- Neural Stem Cells 75
- Neural Tissue 76
- Magnetic Separation 76
- Positive Selection 77
- Negative Selection 77
- Multi-step Selection 77
- TABLE 37 NEW MAGNETIC CELL SEPARATION PRODUCTS 77
- TABLE 37 (CONTINUED) 78
- Laser Microdissection 79
- Platforms 79
- LMPC 79
- Fusion Microdissection 79
- Microscopes, Objectives, Stages and Software 79
- TABLE 38 CURRENT LASER MICRODISSECTION INSTRUMENTS 80
- New Developments 80
- Live Cell Microdissection 80
- Remote Operation 81
- Flow Cytometry 81
- TABLE 39 COMMONLY USED FLUORESCENCE LABELS USED IN FLOW CYTOMETRY 81
- TABLE 39 (CONTINUED) 82
- Cytometer Types 82
- TABLE 40 NEW INSTRUMENTATION PRODUCTS FROM FLOW CYTOMETRY COMPANIES 83
- TABLE 40 (CONTINUED) 84
- Alternative Technologies 84
- Imaging Cytometers 84
- Laser Scanning Cytometers 84
- TABLE 41 NEW PRODUCTS FROM FLOW CYTOMETRY COMPANIES 85
- New Developments 85
- Benchtop Cytometers 85
- Multi-parametric Analyses 85
- CELL AND TISSUE ANALYSIS TECHNOLOGIES 86
- RESEARCH ANTIBODIES 86
- FIGURE 3 SCHEMATIC PRODUCTION OF MONOCLONAL AND POLYCLONAL ANTIBODIES 86
- New Developments 87
- Stem Cell Antibodies 87
- Modification-state Specific Antibodies 87
- New Fluorophores 88
- High-Content Screening 88
- FIGURE 4 BASIC SCHEMATIC OF A TYPICAL HIGH CONTENT SCREENING INSTRUMENT
88
- HCS Instrumentation 89
- Confocal Instruments 89
- Image Sectioning 89
- TABLE 42 FEATURES OF COMMON CONFOCAL HCS INSTRUMENTATION 90
- Widefield Instruments 90
- Illumination Sources 91
- Autofocus 91
- TABLE 43 FEATURES OF COMMON WIDEFIELD HCS INSTRUMENTATION 92
- Software 92
- HCS Applications 92
- Profiling Studies 93
- Screening Studies 93
- New Developments 93
- TABLE 44 NEW PRODUCTS FROM HCS COMPANIES 94
Chapter-6: PATENT LANDSCAPE 21
- INTRODUCTION 95
- CTA INDUSTRY 95
- IMPORTANT CONCEPTS 95
- Priority Dates 95
- Patent Cooperation Treaty 96
- IPC Codes 96
- METHODOLOGY 96
- PATENTS FOR BIOSPECIMEN VENDORS 97
- TABLE 45 NUMBER OF U.S. PATENTS FOR MAJOR BIOSPECIMEN VENDORS, 2009 (NO.
OF PATENTS, % OF PATENTS) 98
- TABLE 46 NUMBER OF INTERNATIONAL PATENTS FOR MAJOR BIOSPECIMEN VENDORS,
THROUGH 2009 (NO. OF PATENTS, % OF PATENTS) 98
- TISSUE MICROARRAY PATENTS 99
- TABLE 47 PATENT PUBLICATIONS FOR TISSUE MICROARRAY TECHNOLOGIES, BY YEAR,
2001 - 2009 (NO. OF PATENTS) 99
- TABLE 48 MAJOR PATENT ASSIGNEES FOR TISSUE MICROARRAY TECHNOLOGIES, 2001 -
2009 (AS OF JUNE 2009) 99
- TABLE 48 (CONTINUED) 100
- TABLE 49 MAJOR IPC CLASSES FOR TISSUE MICROARRAY PATENTS, 2001 - 2009 (NO.
OF PATENTS) 100
- SUMMARY 101
- PATENTS FOR CELL SEPARATION PRODUCT COMPANIES 102
- TABLE 50 NUMBER OF U.S. PATENTS FOR MAJOR CELL SEPARATION PRODUCT
COMPANIES, AS OF JUNE 1, 2009 (NO. OF PATENTS, PERCENT OF PATENTS) 103
- TABLE 51 NUMBER OF INTERNATIONAL PATENTS FOR MAJOR CELL SEPARATION PRODUCT
COMPANIES, AS OF JUNE 1, 2009 (NO. OF PATENTS, PERCENT OF PATENTS) 103
- LASER MICRODISSECTION PATENTS 104
- TABLE 52 PATENT PUBLICATIONS FOR LASER MICRODISSECTION TECHNOLOGIES, BY
YEAR, 1999 - 2009 (NO. OF PATENTS) 104
- TABLE 53 MAJOR PATENT ASSIGNEES FOR LASER MICRODISSECTION TECHNOLOGIES,
1999 - 2009 (NO. OF PATENTS) 105
- TABLE 54 MAJOR IPC CLASSES FOR LASER MICRODISSECTION PATENTS, 1999 - 2009
(NO. OF PATENTS) 106
- FLOW CYTOMETRY PATENTS 106
- TABLE 55 PATENT PUBLICATIONS FOR FLOW CYTOMETRY TECHNOLOGIES, BY YEAR,
1999 - 2009 (NO. OF PATENTS) 107
- TABLE 56 MAJOR PATENT ASSIGNEES FOR FLOW CYTOMETRY TECHNOLOGIES, 2001 -
2009 (NO. OF PATENTS) 107
- TABLE 57 NUMBER OF U.S. PATENTS FOR MAJOR FLOW CYTOMETRY COMPANIES, 1971 -
2009 (NO. OF PATENTS, PERCENT OF PATENTS) 108
- TABLE 58 MAJOR IPC CLASSES FOR FLOW CYTOMETRY PATENTS, 2001 - 2009 (NO. OF
PATENTS) 109
- SUMMARY 109
- PATENTS FOR CELL AND TISSUE ANALYSIS COMPANIES 110
- RESEARCH ANTIBODY PATENTS 110
- TABLE 59 NUMBER OF ANTIBODY-RELATED PATENTS FOR MAJOR RESEARCH ANTIBODY
COMPANIES, AS OF JUNE 1 2009 (NO. OF PATENTS) 111
- Licensing 111
- HIGH CONTENT SCREENING PATENTS 112
- TABLE 60 CELLOMICS PATENTS IN THE HIGH CONTENT SCREENING INDUSTRY 112
- TABLE 61 PATENT PUBLICATIONS RELATING TO HIGH CONTENT SCREENING, BY YEAR,
2004 - 2009 (NO. OF PATENTS) 113
- TABLE 62 MAIN INDUSTRY SEGMENT OF HIGH CONTENT SCREENING PATENT ASSIGNEES,
2004 - 2009 113
- CELL-BASED ASSAY PATENTS 114
- TABLE 63 PATENT PUBLICATIONS RELATING TO CELL-BASED ASSAYS, BY YEAR, 2001
- 2009 (NO. OF PATENTS) 114
- TABLE 64 MAIN INDUSTRY SEGMENT OF CELL-BASED ASSAY PATENT ASSIGNEES, 2001
- 2009 (%) 115
Chapter-7: END USERS 40
- INTRODUCTION 116
- TABLE 65 CELL AND TISSUE ANALYSIS PRODUCT END-USER INDUSTRIES 116
- TABLE 65 (CONTINUED) 117
- ACADEMIC RESEARCH 117
- TABLE 66 NATIONAL INSTITUTES OF HEALTH BUDGET, THROUGH 2009 ($ BILLIONS)
118
- TABLE 67 NATIONAL SCIENCE FOUNDATION BUDGET, THROUGH 2009 ($ BILLIONS) 118
- RESEARCH UNIVERSITIES 119
- TABLE 68 TOP 20 U.S. RESEARCH UNIVERSITIES RECEIVING FEDERAL SUPPORT, 2006
($ MILLIONS) 119
- TABLE 69 FEDERAL RESEARCH SUPPORT GROWTH RATES FOR THE TOP 20 FEDERALLY
FUNDED U.S. RESEARCH UNIVERSITIES, THROUGH 2006 ($ MILLIONS, % CAGR) 120
- TABLE 70 HIGHEST ANNUAL LIFE SCIENCES EXPENDITURES FOR THE TOP 20
FEDERALLY FUNDED U.S. RESEARCH UNIVERSITIES, 2006 ($ MILLIONS) 121
- Translational Research 121
- TABLE 71 MAJOR U.S. CLINICAL AND TRANSLATIONAL SCIENCE AWARD (CTSA)
CENTERS, BY LOCATION, 2009 122
- TABLE 71 (CONTINUED) 123
- TABLE 71 (CONTINUED) 124
- TABLE 71 (CONTINUED) 125
- Government Laboratories 125
- TABLE 72 LIST OF NIH RESEARCH LABS 125
- TABLE 73 NIH INTRAMURAL RESEARCH BUDGET, THROUGH 2009 ($ MILLIONS) 126
- Nonprofit Research Institutes 126
- TABLE 74 LIST OF THE LARGEST U.S. NONPROFIT RESEARCH INSTITUTES, 2008 ($
MILLION) 126
- TABLE 74 (CONTINUED) 127
- BIOPHARMACEUTICAL 127
- Drug Development Process 127
- Biotechnology Industry 128
- TABLE 75 ANNUAL BIOTECHNOLOGY R&D EXPENDITURES OF SELECT INTERNATIONAL
COUNTRIES ($ BILLIONS) 129
- TABLE 76 LIST OF NOTABLE BIOTECHNOLOGY INDUSTRY COMPANIES 129
- Pharmaceutical Industry 130
- TABLE 77 LIST OF NOTABLE PHARMACEUTICAL INDUSTRY COMPANIES 130
- TABLE 78 BIOPHARMACEUTICAL R&D SPENDING, THROUGH 2009 ($ BILLIONS) 131
- HEALTHCARE/CLINICAL 131
- Research Hospitals 131
- INTERNATIONAL ASPECTS 131
- Europe 131
- TABLE 79 TOTAL RESEARCHERS IN EUROPEAN COUNTRIES BY PERFORMANCE SECTOR,
2008 (#, X1,000) 132
- GLOBAL MARKET 132
- Trends in U.S. Research and Development 132
- TABLE 80 U.S. EXPENDITURES ON R&D FINANCING BY SECTOR, THROUGH 2014 ($
BILLIONS) 133
- TABLE 81 U.S. GROSS DOMESTIC EXPENDITURE ON R&D (GERD) FINANCING BY
SECTOR, THROUGH 2014 (%) 133
- Trends in International Research and Development 134
- TABLE 82 GROSS DOMESTIC EXPENDITURE ON R&D (GERD) BY THE PRIVATE BUSINESS
SECTOR IN EUROPEAN COUNTRIES, 2000-2008 (%) 134
- TABLE 83 GROSS DOMESTIC EXPENDITURE ON R&D (GERD) BY THE GOVERNMENT SECTOR
IN EUROPEAN COUNTRIES, 2000-2008 (%) 135
- MARKETS BY PRODUCTS 135
- Biospecimens 135
- Tissue Microarray Use 136
- TABLE 84 PUBMED INDEXED SCIENTIFIC PUBLICATIONS USING TISSUE MICROARRAY,
1998 - 2009 136
- TABLE 85 CLINICAL TRIALS USING TISSUE MICROARRAY, 2001 - 2009 136
- TABLE 85 (CONTINUED) 137
- TABLE 86 PROJECTED GLOBAL SALES OF BIOSPECIMENS, THROUGH 2014 (% MILLIONS)
137
- Cell Separation Products 137
- TABLE 87 PROJECTED GLOBAL SALES OF CSP, THROUGH 2014 ($ MILLIONS) 138
- Laser Microdissection 138
- TABLE 88 PUBMED INDEXED SCIENTIFIC PUBLICATIONS USING LASER CAPTURE
MICRODISSECTION, 1998 - 2009 139
- TABLE 89 CLINICAL TRIALS USING LASER MICRODISSECTON, 1999 - 2009 139
- TABLE 90 PROJECTED GLOBAL SALES OF LMD, THROUGH 2014 ($ MILLIONS) 140
- Flow Cytometry 140
- TABLE 91 PUBMED INDEXED SCIENTIFIC PUBLICATIONS USING FLOW CYTOMETRY OR
FLUORESCENCE ACTIVATED CELL SORTING, 1998 - 2009 140
- TABLE 92 CLINICAL TRIALS USING FLOW CYTOMETRY FLUORESCENCE ACTIVATED CELL
SORTING, BY LOCATION, 2009 (NO. OF TRIALS) 141
- TABLE 93 CLINICAL TRIALS USING FLOW CYTOMETRY OR FLUORESCENCE ACTIVATED
CELL SORTING, BY FUNDING SOURCE, 2002 - 2009 142
- TABLE 94 CLINICAL TRIALS USING FLOW CYTOMETRY OR FLUORESCENCE ACTIVATED
CELL SORTING, BY CONDITION CATEGORY, 2009 142
- TABLE 95 PROJECTED GLOBAL SALES OF THE FLOW CYTOMETRY INDUSTRY THROUGH
2014 ($ MILLIONS) 143
- Cell and Tissue Characterization Products 143
- TABLE 96 PROJECTED GLOBAL SALES OF CTC PRODUCTS, THROUGH 2014 ($
MILLIONS) 143
- Research Antibodies 144
- TABLE 97 PROJECTED GLOBAL SALES OF CTC PRODUCTS, THROUGH 2014 ($
MILLIONS) 144
- HCS/CBA 144
- TABLE 98 PROJECTED GLOBAL SALES OF CTC PRODUCTS, THROUGH 2014 ($
MILLIONS) 144
- TABLE 99 HCS/CBA PRODUCT SEGMENTS, 2009 (%) 145
- MARKETS BY END-USER SEGMENTS 145
- TABLE 100 GLOBAL END-USER MARKETS FOR CELL AND TISSUE ANALYSIS PRODUCTS,
THROUGH 2014 ($ MILLIONS) 146
- Academic Research 146
- TABLE 101 ACADEMIC RESEARCH END-USER SEGMENTS, 2009 (%) 146
- TABLE 102 GLOBAL MARKETS FOR CELL AND TISSUE ANALYSIS PRODUCTS IN
ACADEMIC RESEARCH, THROUGH 2014 ($ MILLIONS) 147
- Biopharmaceutical 147
- TABLE 103 BIOPHARMACEUTICAL END-USER SEGMENTS, 2009 (%) 147
- TABLE 104 MARKETS FOR CELL AND TISSUE ANALYSIS PRODUCTS IN
BIOPHARMACEUTICAL RESEARCH, THROUGH 2014 ($ MILLIONS) 148
- TABLE 105 OTHER MARKETS FOR CELL AND TISSUE ANALYSIS PRODUCTS, THROUGH
2014 ($ MILLIONS) 149
- GEOGRAPHIC MARKETS 149
- General Trends 149
- TABLE 106 REAL GDP GROWTH RATES IN THE UNITED STATES, 2005 - 2010 (PERCENT
CHANGE OVER PREVIOUS YEAR) 150
- TABLE 107 REAL GDP GROWTH RATES IN EUROPEAN COUNTRIES, 2005 - 2010
(PERCENT CHANGE OVER PREVIOUS YEAR) 150
- Global Market Trends 151
- TABLE 108 GEOGRAPHIC MARKETS FOR CELL AND TISSUE ANALYSIS PRODUCTS,
THROUGH 2014 ($ MILLIONS) 151
- Biospecimens 151
- TABLE 109 BIOSPECIMEN GEOGRAPHIC MARKET SHARES, 2009 AND 2014 (PERCENT OF
GLOBAL SALES) 152
- TABLE 110 GEOGRAPHIC MARKETS FOR BIOSPECIMENS, THROUGH 2014 ($ MILLIONS)
152
- CSP 153
- TABLE 111 CELL SEPARATION PRODUCT GEOGRAPHIC MARKET SHARES, 2009 AND 2014
(PERCENT OF GLOBAL SALES) 153
- TABLE 112 GEOGRAPHIC MARKETS FOR CELL SEPARATION PRODUCTS, THROUGH 2014
($ MILLIONS) 154
- CTC Products 154
- TABLE 113 CTC PRODUCT GEOGRAPHIC MARKET SHARES, 2009, AND 2014 (PERCENT OF
GLOBAL SALES) 154
- TABLE 114 GEOGRAPHIC MARKETS FOR CELL AND TISSUE CHARACTERIZATION
PRODUCTS, THROUGH 2014 ($ MILLIONS) 155
Chapter-8: COMPANY PROFILES 28
- BIOSPECIMEN VENDORS (BSV) 156
- TABLE 115 PRODUCTS AND SERVICES OFFERED BY BIOSPECIMEN VENDORS (BSV), 2009
(X REPRESENTS PRODUCT OR SERVICE PROVIDED) 156
- AMERICAN TYPE CULTURE COLLECTION (ATCC) 156
- ANALYTICAL BIOLOGICAL SERVICES, INC. 157
- ASTERAND PLC. 158
- BIOCHAIN INSTITUTE, INC. 159
- BIOSERVE BIOTECHNOLOGIES LTD. 159
- CAPITAL BIOSCIENCES, INC. 160
- CELLECTA, INC. 161
- CURELINE, INC. 161
- CYBRDI, INC. 162
- FOLIO BIOSCIENCES 163
- ILSBIO, LLC. 163
- LIFESPAN BIOSCIENCES, INC. 164
- PROMEDDX, LLC 165
- U.S. BIOMAX, INC. 166
- CELL SEPARATION PRODUCT (CSP) COMPANIES 167
- TABLE 116 PRODUCTS AND SERVICES OFFERED BY CELL SEPARATION PRODUCT (CSP)
COMPANIES, 2009 (X REPRESENTS PRODUCT OR SERVICE PROVIDED) 167
- ACCURI CYTOMETERS, INC. 167
- BECKMAN COULTER, INC. 168
- BD BIOSCIENCES 168
- CARL ZEISS MICROIMAGING, GMBH 169
- LEICA MICROSYSTMES, GMBH 170
- MILLIPORE 170
- MILTENYI BIOTEC 171
- MDS ANALYTICAL TECHNOLOGIES 172
- MOLECULAR MACHINES & INDUSTRIES, GMBH 172
- PARTEC, GMBH 173
- STEM CELL TECHNOLOGIES 173
- WORTHINGTON BIOCHEMCIAL CORPORATION 174
- CELL AND TISSUE CHARACTERIZATION COMPANIES 175
- TABLE 117 PRODUCTS AND SERVICES OFFERED BY CELL & TISSUE CHARACTERIZATION
COMPANIES, 2009 (X REPRESENTS PRODUCT OR SERVICE PROVIDED) 175
- ABCAM, PLC. 175
- CELL SIGNALING TECHNOLOGY, INC. 176
- CELLUMEN, INC. 176
- EBIOSCIENCE, INC. 177
- GE HEALTHCARE BIOSCIENCES 177
- INVITROGEN CORPORATION 178
- MBL INTERNATIONAL 179
- PERKINELMER, INC. 179
- PLATYPUS TECHNOLOGIES, LLC 180
- PROMEGA CORPORATION 180
- ROCHE APPLIED SCIENCE 180
- SIGMA-ALDRICH, INC. 181
- THERMO FISHER SCIENTIFIC, INC. 182
- APPENDIX: GLOSSARY 183
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