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市場調查報告書

糖尿病:藥草生物活性分子vs.醫藥品 - 肉桂的全球市場、競爭企業、機會 - 分析與預測

DIABETES: HERBAL BIOACTIVE MOLECULES VS. PHARMACEUTICAL DRUGS - VOLUME 1: CINNAMON GLOBAL MARKETS, COMPETITORS AND OPPORTUNITIES - 2014-2019 ANALYSIS AND FORECASTS

出版商 Amadee & Company, Inc. 商品編碼 297163
出版日期 內容資訊 英文 328 Pages
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糖尿病:藥草生物活性分子vs.醫藥品 - 肉桂的全球市場、競爭企業、機會 - 分析與預測 DIABETES: HERBAL BIOACTIVE MOLECULES VS. PHARMACEUTICAL DRUGS - VOLUME 1: CINNAMON GLOBAL MARKETS, COMPETITORS AND OPPORTUNITIES - 2014-2019 ANALYSIS AND FORECASTS
出版日期: 2014年03月06日 內容資訊: 英文 328 Pages
簡介

2013年的糖尿病患者數為3億8200萬人,達全球人口的8.3%。至2035年這個數字預計達6億人,為全球人口的10.1%。糖尿病對經濟有很大的影響。譬如美國,2012年包含直接醫療成本1,760億美元的糖尿病診斷成本,推算為2,450億美元。2013年美國的每人糖尿病相關支出是9,800美元。同年全球每人的糖尿病相關支出是1436美元。全球糖尿病藥物療法市場2013年為450億美金,以年度10.5%成長。胰島素的銷售額以年複合成長率14.2%擴大。

本報告提供全球糖尿病市場相關的總括性調查、各國發病率、各種類的經濟影響、糖尿病管理的藥用植物分析、糖尿病管理上肉桂的可能性、生產、包含進出口及進出口公司的全球肉桂市場分析及主要企業簡介,為您概述為以下內容。

摘要整理

簡介

  • 背景
  • 調查方法、資訊來源
  • 統計相關註解

糖尿病市場概要

  • 大流行病
  • 正統派方法
  • 生活方式的變化
  • 減肥
  • 非正統派方法:藥用植物
  • 糖尿病對全球性經濟的影響
  • 糖尿病發病率:各國
  • 糖尿病得病率:各國
  • 每人的糖尿病相關支出:各國
  • 美國的糖尿病的經濟成本
  • 美國的糖尿病的成本:各類型
  • 糖尿病藥物療法企業的市場佔有率
  • 胰島素為最後解決方案
  • 胰島素市場促進成長要素
  • 胰島素市場價值促進要素
  • 胰島素市場成長
  • 胰島素市場成長:各地區
  • 胰島素市場區隔(速效性、預混合料、長時間作用型)
  • GLP-1

藥用植物和糖尿病

  • 傳統的治療
  • 傳統的抗糖尿病藥物
  • 藥用植物:管理糖尿病的安全工具
  • 常見使用的藥用植物的作用機制
  • 經藥理學性檢查的胰島素模仿性或促進胰島素分泌的植物材料及Phytoconstituent
  • 66種植物的降血糖作用及生物活性成分相關確證研究

肉桂和糖尿病

  • 定義
  • 味道、芳香及口味
  • 歷史
  • 農學研究、開發的配合措施
  • 栽培
  • 等級附有
  • 處理、加工
  • 利用
  • 副作用
  • 糖尿病管理的肉桂的醫療潛在性
  • 肉桂的生物學性影響
  • 肉桂的生物學性效果、其他

肉桂市場概要

  • 肉桂vs.藥物療法中醫的生產
  • 生產
  • 肉桂市場
  • 肉桂市場展望
  • 肉桂出口:各國
  • 肉桂的貿易收支:各國
  • 肉桂市場進出口企業

企業簡介

附錄1:糖尿病概要

附錄2:胰島素概要

圖表

目錄

Diabetes is a metabolic disorder arising mainly due to the fault in the production of insulin or mounting resistance to its action. In the case of Diabetes, the most serious problem is the side effect, which occurs due to the accumulation of glucose. This excess glucose is converted into various compounds and also into free radicals, which damage the vital organs and organelles. Diabetes was seriously underrated as a threat to global public health until very recently. Today, Diabetes now ranks as one of the greatest public health challenges in the history of mankind. There were 382 million people with Diabetes, or 8.3% of the global population, in 2013. By 2035, this number will be 10.1%, equal almost 600 million people worldwide.

Diabetes has a very large economic impact. For example, in the US the cost of diagnosed Diabetes in 2012 is estimated at US$245 billion, including $176 billion in direct medical costs. In 2013, the average Diabetes related expenditures per person in the US was USD9,800. Globally, per capita Diabetes related expenditures in 2013 was USD1,436. Further, the global market for Diabetes medications is estimated at approximately USD45 billion in 2013 and is growing 10.5% annually overall, with insulin sales increasing at a 14.2% CAGR.

The currently available antidiabetic drugs manage the blood glucose levels under normal range by supplementing insulin, improving insulin sensitivity, increasing insulin secretion from the pancreas, decreasing glucose absorption from the intestinal tract and/or glucose uptake by tissue cells.

Today, the management of Diabetes without any side effect is still a challenge to the medical fraternity. However, a wide array of plant-derived active principles has demonstrated antidiabetic activity. These natural medicines modulate blood sugar levels through a variety of mechanisms. In some cases their effects are similar to conventional medicines.

This report looks at the use of medicinal plants, rather than pharmaceutical drugs, to both prevent and treat Diabetes. Specifically, it looks in detail at one of these plants: Cinnamon. Cinnamon is widely used and available and the market for it is well developed. The modern literature indicates that the potential antidiabetic properties of Cinnamon have been studied for over 20 years. Numerous trials have been conducted in humans to determine the metabolic effects of Cinnamon.

This report provides:

  • A detailed look at the Diabetes market including its incidence by country now and during the next 20 years, economic impacts and costs by type, especially medications.
  • Analysis of medicinal plants to manage Diabetes including experimental studies on the hypoglycaemic activity and bioactive components of 66 plants.
  • The potential of Cinnamon for the management of Diabetes including its biological effects, molecular mechanisms of action and clinical studies.
  • Analysis of the global market for Cinnamon including production, imports, exports and traders.

Additionally, profiles of 45 leading, public and private companies involved in the Cinnamon industry as producers, distributors, and retailers are given. The report also includes 30 tables and 50 figures.

Table of Contents

CONTENTS

EXECUTIVE SUMMARY

INTRODUCTION

  • Background
  • Methodology and Sources
  • Statistical Notes

DIABETES MARKET OVERVIEW

  • Pandemic
  • Orthodox Approach
  • Lifestyle Changes
  • Diet
  • Nonorthodox Approach: Medicinal Plants
  • Global Economic Impact Of Diabetes
  • World Population Of 20-79 Year Olds: 2013-2035
  • Diabetes Incidence By Country
  • Diabetes Prevalence By Country: 2013-2035
  • Diabetes-Related Expenditure Per Person By Country: 2013-2035
  • Economic Costs Of Diabetes In The US
  • US Diabetes Costs By Type
  • Diabetes Medications Company Market Shares
  • Insulin Is The Final Solution
  • Insulin Market Growth Drivers
  • Insulin Market Value Drivers
  • Insulin Market Growth: 2008-2013
  • Insulin Market Growth By Region
  • Insulin Market Segments (Fast Acting, Premix, Long Acting)
  • GLP-1

MEDICINAL PLANTS AND DIABETES

  • Conventional Treatment
  • Conventional Antidiabetic Drugs
  • Medicinal Plants: A Safe Tool To Manage DM
  • Mechanism Of Action In Commonly Used Medicinal Plants
  • Pharmacologically Screened Insulinomimetic Or Insulin Secretagogues Plant Material And Phytoconstituents
  • Experimental Studies On Hypoglycaemic Activity And Bioactive Components Of 66 Plants
  • Acacia arabica
  • Aegle marmelos
  • Agrimony eupatoria
  • Allium sativum
  • Aloe vera
  • Annona muricata
  • Annona squamosa
  • Asparagus racemosus
  • Bauhinia variegata
  • Berberine
  • Biophytum sensitivum
  • Boerhaavia diffusa
  • Bougainvillea spectabilis
  • Brassica nigra
  • Caesalpinia bonducella
  • Caffeine
  • Camellia sinensis
  • Capsicum frutescens
  • Catharanthus roseus
  • Cinnamon zeylaniucm
  • Citrullus colocynthis
  • Coccinia indica
  • Cornus officinalis
  • Elephantopus scaber
  • Enicostemma littorale
  • Ephedra distachya
  • Eriobotrya japonica
  • Euccalyptus globulus
  • Eugenia jambolana
  • Ficus bengalensis
  • Fermented Unsalted Soybeans
  • Genistein
  • Ginkgo biloba
  • Radix glycyrrhizae
  • Gymnema sylvestre
  • Helicteres isora
  • Hibiscus rosa sinensis
  • Hordeum vulgare
  • Lepechinia caulescens
  • Medicago sativa
  • Momordica charantia
  • Mucuna pruriens
  • Nigella sativa oil
  • Panax ginseng
  • Pandanus odorus
  • Parinari excelsa
  • Prunella vulgaris
  • Psidium guajava
  • Pterocarpus marsupium
  • Radix rehmanniae
  • Rehmania glutinosa
  • Ricinus communis
  • Syzygium cumini
  • Salvia lavandifolia
  • Sarcopoterium spinosum
  • Selaginella tamariscina
  • Semen coicis
  • Smallanthus sonchifolius
  • Stevia rebaudiana
  • Swertia chirayita
  • Swertia punicea
  • Tabernanthe iboga
  • Teucrium polium
  • Tinospora crispa
  • Tribuluks terrestris
  • Trigonella foenum-graecum
  • Zizyphus spina-christi
  • Conclusions
  • Medicinal Plant Market
  • Production
  • Exports
  • Imports
  • Trade Balance

CINNAMON AND DIABETES

  • Definition
  • Genus Cinnamomum
  • Species
  • Flavor, Aroma And Taste
  • History
  • Early History
  • Modern History
  • Agronomy Research And Development Efforts
  • Cultivation
  • Grading
  • Processing
  • Uses
  • Adverse Effects
  • Clinical Potential Of Cinnamon For The Management Of Diabetes
  • Biological Effects Of Cinnamon
  • Cinnamon Has Been Studied For Over 20 Years
  • Molecular Mechanisms Of Action Of Cinnamon
  • Clinical Studies With Cinnamon
  • Conclusions

CINNAMON MARKET OVERVIEW

  • Cinnamon Vs. Medicinal Plant Production
  • Production
  • Cinnamon Market: 1992-2013
  • Cinnamon Market Outlook: 2014-2019
  • Cinnamon Exports By Country
  • Cinnamon Trade Balance By Country
  • Cinnamon Export And Import Companies

COMPANY PROFILES

  • A.A. Sayia & Company, Inc
  • A. Baur & Co (Pvt.) Ltd.
  • ACH Food Companies, Inc.
  • Adam Group
  • Adams Extract & Spice, LLC
  • Ajinomoto Co., Inc.
  • Bart Ingredients Company Ltd
  • Bio Foods Pvt Ltd
  • Bolner's Fiesta Products
  • Ceylon Spice Company
  • C.F. Sauer Company
  • EOAS International
  • Everson Spice Company
  • First Spice Mixing Company
  • Frontier Natural Products Co-op Inc.
  • Goya Foods, Inc.
  • HDDES Group
  • Hong Son Cassia & Star Aniseed Processing Co., Ltd.
  • Horn Company
  • Huong Que Company
  • Indus Organics
  • Integrity Nutraceuticals International Founded
  • Intercom Limited
  • Ishana Spice Exports
  • L B Spices Trading (Private) Limited
  • La Flor Spices
  • La India Packing Company
  • McCormick & Company, Incorporated
  • Monteray Bay Spice Company
  • Mountain Rose Herbs
  • Nature's Agro Products Lanka Company
  • Novo Nordisk A/S
  • Olam International Limited
  • Orient Vietnam Company Limited
  • PT Cassia Co-Op
  • PT Dwiwarna Inti Sejahtera
  • Rathna Producers Cinnamon Exports (Pvt) Ltd.
  • Saboor Chatoor (Private) Limited
  • SC Seasoning Co., Inc.
  • SDS Spices (PVT) Ltd.
  • Spice House USA
  • The Empire Associates
  • Tripper
  • Vanns Spices
  • Whole Foods Market, Inc.
  • Wixon Inc.

APPENDIX 1: DIABETES OVERVIEW

  • Classification
  • Insulin
  • Untreated Diabetes
  • Treated Diabetes
  • Poor Diagnosis Rates
  • Type 2 Medications
  • History
  • Type 1 Diabetes
  • Cause
  • Genetics
  • Environmental
  • Diet
  • Chemicals And Drugs
  • Pathophysiology
  • Diagnosis
  • Tight Glycaemic Control
  • Autoantibodies
  • Prevention
  • Immunosuppressive Drugs
  • Management
  • Pancreas Transplantation
  • Islet Cell Transplantation
  • Stem Cell Educator Therapy
  • Depression
  • Eating Disorders
  • Complications
  • Time Of Diagnosis
  • GAD65 Vaccine
  • T Helper Cell Shift
  • Labile Diabetes
  • Type 2 Diabetes
  • Signs and Symptoms
  • Complications
  • Cause
  • Lifestyle
  • Genetics
  • Medical Conditions
  • Pathophysiology
  • Diagnosis
  • Prevention
  • Management
  • Lifestyle
  • Medications
  • Surgery
  • Metabolic Syndrome
  • History
  • Definitions And Diagnosis
  • IDF
  • WHO
  • EGIR
  • NCEP
  • American Heart Association
  • Other
  • Etiology
  • Pathophysiology
  • Stress
  • Overweight And Obesity
  • Sedentary Lifestyle
  • Aging
  • Type 2 Risk
  • Coronary Heart Disease
  • Lipodystrophy
  • Psychiatric Illnesses
  • Rheumatic Diseases
  • Signs and Symptoms
  • Prevention
  • Therapy
  • Controversy
  • Diabetes And Food Prices

APPENDIX 2: INSULIN OVERVIEW

  • Gene
  • Alleles
  • Regulation
  • Protein Structure
  • Synthesis
  • Release
  • Oscillations
  • Blood Content
  • Signal Transduction
  • Effect On Glucose Uptake and Metabolism
  • Degradation
  • Hypoglycemia
  • Diseases And Syndromes
  • Medication
  • Discovery
  • Extraction And Purification
  • Synthesis
  • Nobel Prizes
  • Glucagon-Like Peptide-1
  • Physiological Functions
  • Leptin
  • Physiology
  • Function
  • Adiposity Signal
  • Interaction With Amylin
  • Metreleptin

TABLES

  • 1. Global Diabetes Market Summary: 2014-2019
  • (Diabetes Cases (Million), Diabetes Related Expenditures Per Person (USD), Total Diabetes Related Expenditures (USD Billion), Total Diabetes Medications Demand (USD Billion), Medicinal Plants Production (USD Billion), Cinnamon Production (USD Million)
  • 2. Population Of 20-79 Year Olds Ranked For The World
  • And 218 Countries Plus Growth Rates: 2013-2035
  • 3. Diabetes Cases (1000s) Among 20-79 Year Olds Ranked For The World And 218 Countries Plus Growth Rates: 2013-2035
  • 4. Diabetes National Prevalence (%) Ranked For The World And 218 Countries: 2013-2035
  • 5. Diabetes-Related Expenditures Per Person With Diabetes For The World And 218 Countries (USD): 2013
  • 6. US Health Care Expenditures By Diabetes Status And Type Of Service (USD Million): 2012
  • 7. US Health Care Expenditures Attributed To Diabetes By Age Group And Type Of Service (USD Million): 2012
  • 8. US Per Capita Health Care Expenditures Attributed To Diabetes By Age Group And Type Of Service (USD Million): 2012
  • 9. US Health Care Expenditures Attributed To Diabetes By Medical Condition And Type Of Service (USD Million): 2012
  • 10. US Annual Per Capita Health Care Expenditures By Diabetes Status (Actual Dollars): 2012
  • 11. Existing Synthetic Drugs For Type 2 DM In Market And Their Molecular Targets, Site Of Action And Adverse Reactions
  • 12. Commonly Used Conventional And Natural Medicines For Diabetes
  • 13. List Of Plants Having Antidiabetic Activity
  • 14. List of Plants Having Insulin Mimetic Or Insulin Secreatory Activity
  • 15. List Of Plants Phytoconstituents Having Insulin Secretagogues Or Insulin Mimetic Activity
  • 16. Global Medicinal Plant Exports By Country And Growth Rate (USD Thousands): 2008-2012
  • 17. Global Medicinal Plant Imports By Country And Growth Rate (USD Thousands): 2008-2012
  • 18. Global Medicinal Plant Trade Balance By Country And Growth Rate (USD Thousands): 2008-2012
  • 19. Summary Of Human Studies Where Patients With Type 2 Diabetes, Metabolic Syndrome, Impaired Fasting Glucose And Associated Diseases Were Treated With Cinnamon
  • 20. Global Medicinal Plant Vs. Cinnamon Production (USD Million): 2014-2019
  • 21. Global Cinnamon Production By Country (Metric Tons): 1982-2012
  • 22. Global Cinnamon Market (USD Million, Metric Tons, Average Selling Price): 1992-2013
  • 23. Global Cinnamon Market (USD Million, Metric Tons, Average Selling Price): 2014-2019
  • 24. Global Exports Of Cinnamon For World And 121 Countries (USD Thousand): 2008-2012
  • 25. Global Imports Of Cinnamon For World And 198 Countries (USD Thousand): 2008-2012
  • 26. Global Trade Balance Of Cinnamon For World And 202 Countries (USD Thousand): 2008-2012
  • 27. 481 Cinnamon Export Companies By Country (Name, Product/Service Categories Traded, Employees, Country, Website): 2014
  • 28. 201 Cinnamon Import Companies By Country (Name, Product/Service Categories Traded, Employees, Country, Website): 2014
  • 29. Comparison Of Type 1 And Type 2 Diabetes
  • 30. Commonly Prescribed Products For The Treatment Of Type 2 Diabetes

FIGURES

  • 1. Global Diabetes Medications Market By Treatment Class (GLP-1, Insulin, OAD): 2003-2013
  • 2. Global Diabetes Medications Market Shares By Company (%): 2003-2013
  • 3. Progression Of Type 2 Diabetes And Treatment Intensification
  • 4. Distribution Of Patients And Value Across Treatment Classes
  • 5. Global Insulin Market Growth By Component: 2008-2013
  • 6. Global Insulin Market: Device Penetration Vs. Modern Insulin Penetration
  • 7. Global Modern Insulin Volume Company Market Shares
  • 8. Insulin Market Size And Growth By Region, Volume Composition, Volume Market Shares By Company: 2012-2013
  • 9. Regional (North America, Europe, China, Japan, Korea) Insulin Market Volume Growth Rates: 2003-2013
  • 10. Regional (North America, Europe, China, Japan, Korea) Insulin Volume Market Split: 2003-2013
  • 11. Action Profiles Of Insulins By Type
  • 12. Global Insulin Market Volume And Growth By Segment: 2008-2013
  • 13. Global GLP-1 Market Value And Market Share: 2008-2013
  • 14. GLP-1 Market By Region (%): 2013
  • 15. US GLP-1 Market-Victoza® Vs. Other GLP-1(Value, TRx Scripts, % of Diabetes Care): 2010-2013
  • 16. Germany, UK And France Markets for GLP-1: Victoza® Vs. Other GLP-1 Products (Value, % of Diabetes Care): 2009-2013
  • 17. Effects Of Phytochemicals in Insulin Secretion And Pancreatic-Β-cell Apoptosis
  • 18. Cinnamomum verum
  • 19. Cinnamon Trees
  • 20. Cinnamon Products
  • 21. Flow Diagram Of Cinnamon Processing
  • 22. Mechanisms Of Action Of Cinnamon In Relevant Metabolic Pathways
  • 23. Novo Nordisk Diabetes Care Revenues By Segment (DKK Billion): 2013
  • 24. Novo Nordisk MAT Diabetes Care Sales Growth By Segment (%): 2008-2013
  • 25. Novo Nordisk Global And Regional Insulin Market Shares: 2013
  • 26. Novo Nordisk Revenue And Growth By Product and Region: 2009-2013
  • 27. Novo Nordisk Volume Market Share Across Insulin Classes
  • 28. Novo Nordisk Brand Names, Product Types, Sales, Market Shares, Patent Expirations: 2013
  • 29. Novo Nordisk's Modern Insulins Volume Market Share By Segment
  • 30. Novo Nordisk Product Growth And Market Shares By Segment: 2008-2013
  • 31. Novo Nordisk Modern Insulin US Market Share By Market Segment: 2008-2013
  • 32. US Insulin Supplier Volume Market Shares (%): 2013
  • 33. European Insulin Supplier Volume Market Shares (%): 2013
  • 34. Chinese Insulin Supplier Volume Market Shares (%): 2013
  • 35. Japanese Insulin Supplier Volume Market Shares (%): 2013
  • 36. Novo Nordisk Current And Future Product Portfolio
  • 37. Novo Nordisk R&D Pipeline: Diabetes And Obesity
  • 38. Insulin Secretion Profile
  • 39. Insulin Enables Glucose To Become Energy
  • 40. Insulin Level Vs. Time Of Day
  • 41. Diabetes Diagnosis And The Rule Of Halves
  • 42. Glycaemic Control In Selected Countries (%)
  • 43. Diabetes Prevalence And Diagnosis Rates By Region: 2013
  • 44. Main Symptoms of Diabetes
  • 45. Risk Reduction By Class From Lowering HbA1c By 1%-Point
  • 46. Insulin Synthesis Process
  • 47. Insulin Oscillations
  • 48. Idealized Diagram Of Blood Sugar Fluctuation
  • 49. Effect Of Insulin On Glucose Uptake And Metabolism
  • 50. The Structure Of Insulin
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