第1回 疼痛之新穎療法
5月12日(一)∼13日(二)
OPENING KEYNOTE ADDRESS
Catherine Abbadie, Ph.D., Senior Research Fellow, Merck & Co., Inc.
IN HOT PURSUIT ONE: TRPV
Targeting TRPV1 Receptor Antagonist for Treatment of Pain
Chih-Hung Lance Lee, Ph.D., Senior Group Leader, Abbott Neuroscience
Design & Synthesis of TRPV1 Antagonists
Gurdip Bhalay, Ph.D., Chemistry Project Team Head, Novartis Institutes of BioMedical Research
IN HOT PURSUIT TWO: CB1 & CB2
Identification and Exploration of a Novel Series of Heterocyclic Cannabinoid Receptor Agonists for the Treatment of Pain
Paul D. Ratcliffe, Ph.D., Team Leader, Department of Medicinal Chemistry, Organon Laboratories Ltd, a part of Schering-Plough Corporation
IN HOT PURSUIT THREE: P1, P2X3, P2X7
Purinergic Receptor Antagonists: Novel Treatments for Inflammatory and Neuropathic Pain
David S. Carter, Ph.D., Research Scientist, Roche Palo Alto
IN HOT PURSUIT FOUR: Potassium & Sodium Channels
Potassium and Sodium Channel Modulators Designed to Target Neuropathic Pain
Robert Atkinson, Ph.D., Senior Research Investigator, Medicinal Chemistry, Icagen, Inc.
IN HOT PURSUIT FIVE: New Opportunities for Targeting Inflammatory Pain
Development of Peripheral Kappa Opioid Analgesics: Targeting Pain and Inflammation at its Source
Rob Spencer, Ph.D., Director, Preclinical Development, Cara Therapeutics, Inc.
Design and Pharmacological Properties of a Novel Series of Dithiolethione Compounds as Non-Steroidal Anti-Inflammatory Drugs with Minimal Gastrointestinal Toxicity
Bevyn Jarrott, Professor, Florey Neuroscience Institutes, University of Melbourn
RECOMMENDED SHORT COURSE *Separate Registration Required
(SC6) 創藥和疼痛之動物模式 (5月13日 9:00am - 12:00pm)
This short course will highlight specific steps to building better animal models for drug development in the pain area. The session will begin by addressing the ethical considerations of animal research and a framework for identifying appropriate species and models (e.g. surgical v. irritant, disease specific v. general). You will also learn how to better identify and understand the critical biological, histological and electrophysiological endpoints of your programs. Special attention to the applications of animal research in inflammatory, neuropathic and cancer pain will be given during this session.
