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蛋白質的精製和回收 1月9日∼10日 以使用改革「已實證效果」手法的蛋白質精製技術之主題為重點的此部會，預定進行由專家介紹因應運用生產率高的細胞培養技術衍生出的各種要求能獲得的經驗等個案研究。此外，透過有關affinity tag、電氣泳動法、離心分離、過濾、層析法 （chromatography）、導入卓越作業（operational excellence）計畫製程效率化等詳細的發表，除公布使精製製程最佳化的方法外，加上以往型的哺乳類系，亦介紹包含因應大腸菌和桿狀病毒科(Baculoviridae)、酵母等「特殊」系各種發現系的精製技術。 層析法（chromatography） Capture and Resolution of mAb Charge Variants with Cation Exchangers - Advances and Perspectives Giorgio Carta, Ph.D., Lawrence R. Quarles Professor, Department of Chemical Engineering, University of Virginia Multi-Dimensional Chromatography for Monitoring Quality Attributes of Monoclonal Antibodies in Cell Culture Process Methal Albarghouthi, Ph.D., Senior Scientist, Analytical Biochemistry, MedImmune, LLC
親和性精製 Ultra Pure Functional Protein Recovery with a Novel High Affinity EF Hand Fusion Protein System David O�fConnell, Ph.D., Senior Scientist, School of Medicine, University College Dublin Quantification of a PEGylated Peptide Drug Candidate in Human Plasma Using Immuno-Affinity Purification with an Anti-PEG Antibody Followed by LC/LC-MS/MS John T. Mehl, Ph.D., Senior Research Chemist, Vaccine Bioprocess Research & Development, Merck Research Laboratories
改革製程 Adaptation of Precipitation Technologies for Improved Downstream Efficiency for Monoclonal Antibody Production Alahari Arunakumari, Ph.D., President, AHA Bioconsultants LLC One-Second Isolation/Immunoprecipitation of Weak Protein Complexes Using a Microfluidic IFAST Device Richard R. Burgess, Ph.D., Professor, Oncology, McArlde Lab for Cancer Research, School of Medicine, University of Wisconsin, Madison Process Development of Primary Recovery Steps for a High Cell Density Product Stream Jessica Molek, Ph.D., Principal Scientist, Downstream Process Development, GlaxoSmithKline Rhobust® Technology – Process Intensification Through Direct Product Capture Spencer Reynolds, Director, Business Development, DSM Biologics
新的蛋白質和精製困難的蛋白質 Differential Filtration Analysis: An Enabling Technology for Membrane Proteins (and Soluble Proteins too!) Michael C. Wiener, Ph.D., Associate Professor, Molecular Physiology and Biological Physics, Center for Membrane Biology, University of Virginia
Expression and Purification of Novel Viral Fusion Proteins for Drug Target Discovery David Bienvenue, Ph.D., Associate Director, VLST Corporation Protease-Based Nanomachines Philip N. Bryan, Professor, Institute for Bioscience and Biotechnology Research, and Department of Bioengineering, University of Maryland 標籤技術 Expression and in vivo Ulp1-Mediated Cleavage of SUMO Fusion Proteins Albert J. Courey, Ph.D., Professor, Chemistry & Biochemistry, UCLA The CK-Tag: A Novel Solution for Protein Expression and Purification David Smith, Ph.D., Senior Scientist, Nuffield Department of Clinical Laboratory Sciences, University of Oxford
監視精製中蛋白質的狀態 Analysis of Protein Samples by Microfluidics: the Pros and Cons Sabine Suppmann, Ph.D., Protein Expression and Purification Core Facility, Max Planck Institute of Biochemistry |
