脊椎外科：全球產品、技術、市場動向及機會：2008年至2017年

Abstract

This report details the complete range of products and technologies in the surgical management of spine disorders, diseases and trauma, from grafts, demineralized bone, fusion, stabilization, disc/nucleus replacement, vertebroplasty, kyphoplasty, imaging, minimally invasive surgical technologies, energy-based therapies and biologics. The report details current clinical and technology developments in this huge and rapidly growing worldwide market, with data on products in development and on the market; market size and forecast; competitor market shares; competitor profiles; and market opportunity.

This report is a detailed market and technology assessment and forecast of the products and technologies in the management of diseases and disorders of the spine. The report describes diseases and disorders of the spine, encompassing congenital disorders, inflammatory and infectious diseases; degenerative diseases; herniations, stenoses, myelopathies and other "mechanical" disorders of the spine; spinal trauma; tumors of the spine; and others. The report characterizes the patient populations, their current clinical management, and trends in clinical management as new techniques and technologies are expected to be developed and emerge. The report details the currently available products and technologies, and manufacturer offerings. The report details products and technologies under development and markets for each in spine surgery. The report provides a current and forecast assessment of the worldwide markets for these technologies, with geographic segmentation by U.S. & Canada, European Union (detailing France, United Kingdom, Germany, Italy and Spain), Japan and Rest of World. The report provides emphasis on the market impact of new technologies through the coming decade, profiling over 75 active companies in this industry, with comprehensive detail on key companies, providing data on their current products, current market position and products under development.

• Worldwide scope
• Geographic segmentation
• Detailed company profiles
• Forecasts to 2017
• Competitor market shares by segment

Methodology

MedMarket Diligence Reports are produced through primary and secondary research. Data is gathered from published sources on products and technologies on the market and under development. Clinicians and industry representatives are interviewed for their knowledge and insights on product development, market development, clinical practice and trends associated with the evolving use of technologies. Secondary data is used to corroborate and support assessments and projections. Reports are written and researched by industry insiders, whose familiarity with the companies, industry dynamics and other marketplace specifics facilitate the research process and ensure high quality and thorough reports.

Table of Contents

Executive Summary

• Non-fusion products
• Disc arthroplasty (total disc replacement)
  • Nuclear arthroplasty
• European Union
• Asia-Pacific
• Rest of World
• Selected company-related events
  • Medtronic
  • LDR Spine
  • Synthes Spine
  • Disc Motion Technologies
• Spine Structure
• Products and technologies
• CMS, carriers reverse decision on artificial discs
• Cost effectiveness

Section 1: the spine: structure, disorders, treatment

• 1.1 Overview: Spine Structure
• 1.2 Diseases and disorders of the spine
  • 1.2.1 Congenital Disorders
  • 1.2.2 Inflammatory and Infectious Diseases of the Spine
  • 1.2.3 Degenerative Diseases of the Spine
  • 1.2.4 Mechanical Disorders of the Spine
  • 1.2.5 Spinal Trauma
  • 1.2.6 Tumors of the Spine
• 1.3 Spine management
  • 1.3.1 Clinical: the SPORT Study
  • 1.3.2 Diagnostic studies
  • 1.3.3 Surgical procedures of the spine
  • 1.3.4 Minimally Invasive Procedures
  • 1.3.5 Minimally Invasive Bone Grafting Procedures
  • 1.3.6 Acupuncture for treatment of chronic low back pain

Section 2: products and technologies

• 2.1 Bone grafts and bone graft substitutes
• 2.2 Demineralized bone matrix (DBM)
  • 2.2.1 Particle based DBM
  • 2.2.2 Biomimetic matrix bone substitute
  • 2.2.3 Bone morphogenic proteins (BMPs)
• 2.3 Spinal fusion and fixation products and technologies
  • 2.3.1 Spine surgery instrumentation
  • 2.3.2 Cervical fusion devices
  • 2.3.3 Interbody fusion devices
  • 2.3.4 Posterior dynamic stabilization systems
• 2.4 Non-fusion products and technologies
  • 2.4.1 Disc arthroplasty
  • 2.4.2 Nuclear arthroplasty and nuclear disc prostheses
  • 2.4.3 Facet repair and replacement
• 2.5 Vertebroplasty and kyphoplasty
  • 2.5.1 Vertebral compression fracture treatment technologies
• 2.6 Advances in spinal image-guided surgery
  • 2.6.1 Medtronic' s StealthStation
  • 2.6.2 GE Healthcare' s Fluoro-Spine
  • 2.6.3 Elekta' s Axesse system
  • 2.6.4 Zimmer' s ORTHOsoft NavitrackR FluoroSpineR System
• 2.7 Products and technologies for minimally invasive spinal surgery
  • 2.7.1 ArthroCare' s spineWand
  • 2.7.2 Medtronic' s MAST"! Portfolio
  • 2.7.3 NuVasive' s Maximum Access Surgery (MAS)
  • 2.7.4 Abbott Spine' s Harmony Retractor
  • 2.7.5 Globus transforaminal TDR device
• 2.8 Energy-based therapies
  • 2.8.1 Bone growth stimulators
  • 2.8.2 Intradiscal Electrothermal Therapy (IDET)
• 2.9 Biologics

Section 3: Market Size, Forecast and Competitor Shares

• 3.1 Global market size, forecast and competitor shares
• 3.2 USA & Canada
  • 3.2.1 Bone grafts and bone graft substitutes
  • 3.2.2 Spinal fusion and fixation products
  • 3.2.3 Non-fusion products
  • 3.2.4 Vertebroplasty and Kyphoplasty
  • 3.2.5 Interspinous process spacers (ISP)
  • 3.2.6 Computer assisted image guided surgery products
• 3.3 European Union
  • 3.3.1 United Kingdom
  • 3.3.2 France
  • 3.3.3 Germany
  • 3.3.4 Italy
  • 3.3.5 Spinal fusion and fixation products
  • 3.3.6 Non-fusion products
  • 3.3.7 Total disc replacement
  • 3.3.8 Nucleus replacement
  • 3.3.9 Interspinous process spacers (ISPs)
  • 3.3.10 Kyphoplasty
  • 3.3.11 Image Guided Surgery Products Market
• 3.4 Asia-Pacific
  • 3.4.1 Spinal fusion and fixation products
  • 3.4.2 Non-fusion products
  • 3.4.3 Image guided surgery products
• 3.5 Rest of World

Section 4: regulatory, cost and reimbursement issues

• 4.1 Regulatory Issues Associated with Spine Treatments, Materials and Methods
  • 4.1.1 Regulatory issues regarding off-label usage
  • 4.1.2 Changes to European Device Safety Regulations
  • 4.1.3 NICE and dynamic stabilization procedures
• 4.2 Reimbursement Developments
  • 4.2.1 CMS, carriers reverse decision on artificial discs
  • 4.2.2 CMS reverses stand on two spinal fusion procedures
  • 4.2.3 ArthroCare and DiscoCare
  • 4.2.4 Bone growth factor reimbursement issues
  • 4.2.5 CMS investigates Thermal Intradiscal Therapy
  • 4.2.6 CMS announces new ICD-9-CM spinal procedure codes
  • 4.2.7 Wellmark and energy-based treatments
• 4.3 Cost effectiveness

Section 5: Company profiles

• 5.1 Abbott Spine
• 5.2 AlloSource
• 5.3 Alphatec Holdings, Inc.
• 5.4 Altiva Corporation
• 5.5 Anulex Technologies, Inc.
• 5.6 ApaTech
• 5.7 Applied Spine Technologies
• 5.8 ArthroCare Corporation
• 5.9 A-Spine Holding Group Corporation
• 5.10 Axial Biotech
• 5.11 AxioMed Spine Corporation
• 5.12 B. Braun/Aesculap, Inc.
• 5.13 BioAssets Development Corporation
• 5.14 Biomet
• 5.15 Biorthex, Inc.
• 5.16 Blackstone Medical, Inc
• 5.17 BrainLAB
• 5.18 Cardinal Health
• 5.19 Cervitech
• 5.20 Changzhou Kanghui
• 5.21 Co.Don AG
• 5.22 CoLigne AG
• 5.23 Cook Group
• 5.24 CoreSpine Technologies LLC
• 5.25 Corin Group
• 5.26 Cortek, Inc
• 5.27 Cryolife, Inc.
• 5.28 Cyberkinetics Neurotechnology Systems
• 5.29 Cytori Therapeutics
• 5.30 DePuy Spine/J&J
• 5.31 Disc Dynamics
• 5.32 Disc Motion Technologies
• 5.33 Encore Medical Corporation
• 5.34 Facet Solutions
• 5.35 Fixano
• 5.36 GE Healthcare
• 5.37 Gentis, Inc
• 5.38 Globus Medical
• 5.39 GMReis
• 5.40 HydroCision
• 5.41 Innovative Spinal Technologies
• 5.42 Integra LifeSciences
• 5.43 Integra Radionics
• 5.44 Interpore Cross
• 5.45 Interventional Spine
• 5.46 Invibio
• 5.47 LDR Holding Corporation
• 5.48 LifeNet Health, Inc.
• 5.49 Mazor Surgical Technologies Ltd
• 5.50 Medtronic, Inc
• 5.51 Medtronic Sofamor Danek
• 5.52 Medtronic Surgical Navigation
• 5.53 Mekanika, Inc.
• 5.54 Merck & Co., Inc.
• 5.55 MiMedx
• 5.56 Misonix
• 5.57 MTF (Musculoskeletal Transplant Foundation)
• 5.58 NPS Pharmaceuticals
• 5.59 N Spine, Inc. (Synthes)
• 5.60 NuVasive, Inc.
• 5.61 Ortho Development Corporation
• 5.62 Orthofix International, N.V.
• 5.63 OrthoVita
• 5.64 Osiris Therapeutics
• 5.65 Osteotech, Inc.
• 5.66 Ortosintese
• 5.67 Paradigm Spine, LLC
• 5.68 Pitkar
• 5.69 Praxim
• 5.70 Ranier Technology Limited
• 5.71 Raymedica, Inc.
• 5.72 Regeneration Technologies, Inc
• 5.73 Scient' X
• 5.74 SeaSpine, Inc.
• 5.75 Sharma Surgical
• 5.76 Small Bone Innovations, LLC
• 5.77 Smart Disc
• 5.78 Smith & Nephew
• 5.79 SpinalMotion
• 5.80 SpineMedica Corporation
• 5.81 Spineology
• 5.82 SpineOvations
• 5.83 SpineVision Inc
• 5.84 Spine Wave, Inc.
• 5.85 Stryker Corporation
• 5.86 Stryker Instruments
• 5.87 Stryker Spine
• 5.88 Synthes Spine Solutions
• 5.89 Theken Spine
• 5.90 TranS1, Inc.
• 5.91 Trimedyne, Inc.
• 5.92 Ulrich Medical GmbH
• 5.93 Valleylab
• 5.94 Vertebron Inc.
• 5.95 Waston Medical
• 5.96 Wright Medical Technology
• 5.97 X-spine Systems, Inc.
• 5.98 Zimmer Spine

Appendix: Company Directory

List of Exhibits

• Exhibit ES-1: Total Global Spine Surgery Market, 2008-2017
• Exhibit ES-2: Total Global Spine Surgery Market, 2008-2017
• Exhibit ES-3: Global Spine Surgery Market by Segment, in USD Terms
• Exhibit ES-4: Global Spine Surgery Market by Percentage and Segments, 2008
• Exhibit ES-5: Major Spine Market Segments, 2008-2017
• Exhibit ES-6: Key Factors Driving Growth in the Global Spine Surgery Market
• Exhibit ES-7: Global Spine Surgery Market Shares, 2008
• Exhibit ES-8: US & Canadian Market for Spine Surgery Devices
• Exhibit ES-9: US Company Market Shares for Spine Surgery Devices, 2008
• Exhibit ES-10: Total Global Spine Surgery Market, by Region, 2008
• Exhibit ES-11: Total EU Spine Surgery Market, 2008-2017
• Exhibit ES-12: Total EU Spine Surgery Market, 2008-2017
• Exhibit ES-13: EU Spine Surgery Market Shares, 2008
• Exhibit ES-14: Asia-Pacific: Total Spine Surgery Market, 2008-2017
• Exhibit ES-15: Asia-Pacific: Total Spine Surgery Market, 2008-2017
• Exhibit ES-16: Asia-Pacific: Spine Surgery Market Shares, 2008
• Exhibit ES-17: Rest of World Spine Surgery Market Shares, 2008
• Exhibit ES-18: ROW, Spine Surgery Markets, 2008-2017
• Exhibit ES-19: Lateral and Posterior Views of the Spine
• Exhibit ES-20: Human Spine Structure Showing Vertebrae, Intervertebral Discs, and Spinal Cord
• Exhibit ES-21: US Census figures and projections, ages 65 and up, 1900-2050.
• Exhibit ES-22: Number & Percentage of U.S. Population over Age 65, 1910- 2050
• Exhibit ES-23: Mechanical Disorders of the Spine
• Exhibit ES-24: Start-up companies and areas of interest
• Exhibit ES-25: CPT spinal fusion codes now allowed by CMS
• Exhibit ES-26: Summary of CMS Medicare cost data

• Exhibit 1-1: Lateral and Posterior Views of the Spine
• Exhibit 1-2: Human Spine Structure Showing Vertebrae, Intervertebral Discs, and Spinal Cord
• Exhibit 1-3: Components of the Human Spine
• Exhibit 1-4: US Census figures and projections, ages 65 and up, 1900-2050.
• Exhibit 1-5: Number & Percentage of U.S. Population over Age 65, 1910- 2050
• Exhibit 1-6: Congenital Disorders of the Spine
• Exhibit 1-7: Inflammatory and Infectious Diseases of the Spine
• Exhibit 1-8: Degenerative Diseases of the Spine
• Exhibit 1-9: Estimated Annual Number of Fractures Due to Osteoporosis in the U.S. (Total: Over 1.5 Million)
• Exhibit 1-10: Mechanical Disorders of the Spine
• Exhibit 1-11: Location, Effects, and Incidence of Major Lumbar Disc Herniations
• Exhibit 1-12: Clinical Features- Radiculopathy by Spinal Level
• Exhibit 1-13: Causes of Trauma to Spinal Regions
• Exhibit 1-14: Tumors of the Spine
• Exhibit 1-15: Traditional (“Open”) Spinal Procedures
• Exhibit 1-16: Estimated Number of Spinal Fusion Procedures Performed in the U.S., 2005- 2015
• Exhibit 1-17: Minimally Invasive Spinal Procedures

• Exhibit 2-1: Spinal Allografts: Vendors and Products
• Exhibit 2-2: Hydroxyapatite Bone Substitutes: Vendors, Products
• Exhibit 2-3: Bone growth stimulatory proteins, peptides and devices
• Exhibit 2-4: Fusion instrumentation companies
• Exhibit 2-5: Developers of Interspinous Process Spacers
• Exhibit 2-6: Developers of Total Disc Replacements
• Exhibit 2-7: Artificial Cervical Discs Currently in US Clinical Trials
• Exhibit 2-8: Artificial Cervical Discs Currently Available in the EU
• Exhibit 2-9: Total disc replacement devices
• Exhibit 2-10: Developers of Prosthetic Disc Nuclei
• Exhibit 2-11: Nucleus replacement implants
• Exhibit 2-12: Current nucleus arthroplasty motion preservation IDE pilot studies
• Exhibit 2-13: Bone growth stimulatory proteins, peptides and devices
• Exhibit 2-14: Cellular therapies: manufacturers and product
• Exhibit 2-15: Other start-up companies and areas of interest

• Exhibit 3-1: Total Global Spine Surgery Market, 2008-2017
• Exhibit 3-2: Total Global Spine Surgery Market, 2008-2017
• Exhibit 3-3: Global Spine Surgery Market by Segment, in USD Terms
• Exhibit 3-4: Global Spine Surgery Market by Percentage and Segments, 2008
• Exhibit 3-5: Key Factors Driving Growth in the Global Spine Surgery Market
• Exhibit 3-6: Major Spine Market Segments, 2008-2017
• Exhibit 3-7: Global Spine Surgery Market Shares, 2008
• Exhibit 3-8: US & Canadian Market for Spine Surgery Devices
• Exhibit 3-9: US & Canadian Market for Spine Surgery Devices
• Exhibit 3-10: US Company Market Shares for Spine Surgery Devices, 2008
• Exhibit 3-11: Usage of Bone Grafts and Bone Graft Substitutes in Spinal Fusion Procedures (excluding BMPs)
• Exhibit 3-12: US Market for Bone Graft Substitutes
• Exhibit 3-13: US Market for Spine-Related Orthobiologics, 2008-2017
• Exhibit 3-14: US & Canadian Market for Spinal Fusion and Fixation Devices
• Exhibit 3-15: Number of Spinal Fusions
• Exhibit 3-16: US & Canadian Market for Spinal Fusion and Fixation Devices
• Exhibit 3-17: US Market Shares, Spinal Fusion and Fixation Devices, 2008
• Exhibit 3-18: US Market Shares, Spinal Fusion and Fixation Devices, 2008
• Exhibit 3-19 Total US Non-Fusion Device Market
• Exhibit 3-20: Total US Non-Fusion Device Market
• Exhibit 3-21: US Annulus Repair Market, 2009-2015
• Exhibit 3-22: US Annulus Repair Market, 2009-2015
• Exhibit 3-23: Total Market for Disc Arthroplasty (Cervical Plus Thoracolumbar)
• Exhibit 3-24: US Market for Cervical Disc Replacement
• Exhibit 3-25: US Market for Cervical Disc Replacement
• Exhibit 3-26: US Market for Thoracolumbar Disc Replacement
• Exhibit 3-27: US Market for Thoracolumbar Disc Replacement
• Exhibit 3-28: US & Canadian Markets for Nuclear Arthroplasty
• Exhibit 3-29: US Market for Nucleus Replacement
• Exhibit 3-30: Total US Market for Vertebroplasty and Kyphoplasty
• Exhibit 3-31: US Market for Vertebroplasty
• Exhibit 3-32: US Market for Vertebroplasty
• Exhibit 3-33: US Market for Kyphoplasty
• Exhibit 3-34: US Market for Kyphoplasty
• Exhibit 3-35: 2008 US Market Shares, Combined Vertebroplasty/Kyphoplasty
• Exhibit 3-36: US Interspinous Process Spacers Market, 2008-2017
• Exhibit 3-37: US Interspinous Process Spacers Market, 2008-2017
• Exhibit 3-38: US Market for Image Guided Surgery Devices
• Exhibit 3-39: US Market for Image Guided Surgery Devices
• Exhibit 3-40: US Competitor Shares, Image Guided Surgery Devices, 2008
• Exhibit 3-41: Total Global Spine Surgery Market, by Region, 2008
• Exhibit 3-42: Total EU Spine Surgery Market, 2008-2017
• Exhibit 3-43: Total EU Spine Surgery Market, 2008-2017
• Exhibit 3-44: EU Spine Surgery Market by Segment, in USD
• Exhibit 3-45: EU Spine Surgery Market by Percentage and Segments, 2008
• Exhibit 3-46: EU Spine Surgery Market Shares, 2008
• Exhibit 3-47: United Kingdom: Total Spine Surgery Market, 2008-2017
• Exhibit 3-48: United Kingdom: Total Spine Surgery Market, 2008-2017
• Exhibit 3-49: UK: Total Spine Surgery Market Shares, 2008
• Exhibit 3-50: France: Total Spine Surgery Market, 2008-2017
• Exhibit 3-51: France: Total Spine Surgery Market, 2008-2017
• Exhibit 3-52: France: Total Spine Surgery Market Shares, 2008
• Exhibit 3-53: Germany: Total Spine Surgery Market, 2008-2017
• Exhibit 3-54: Germany: Total Spine Surgery Market, 2008-2017
• Exhibit 3-55: Germany: Total Spine Surgery Market Shares, 2008
• Exhibit 3-56: Italy: Total Spine Surgery Market, 2008-2017
• Exhibit 3-57: Italy: Total Spine Surgery Market, 2008-2017
• Exhibit 3-58: Italy: Total Spine Surgery Market Shares, 2008
• Exhibit 3-59: Total EU Spine Fusion and Fixation Market, 2008-2017
• Exhibit 3-60: Total EU Spine Fusion and Fixation Market, 2008-2017
• Exhibit 3-61: United Kingdom: Spinal Fusion and Fixation Market, 2008-2017
• Exhibit 3-62: France: Spinal Fusion and Fixation Market, 2008-2017
• Exhibit 3-63: Germany: Spinal Fusion and Fixation Market, 2008-2017
• Exhibit 3-64: Italy: Spine Fusion and Fixation Market, 2008-2017
• Exhibit 3-65: Total EU Non-Fusion Market, 2008-2017
• Exhibit 3-66: Total EU Non-Fusion Market, 2008-2017
• Exhibit 3-67: United Kingdom: Non-fusion Products Market, 2008-2017
• Exhibit 3-68: France: Total Non-Fusion Products Market, 2008-2017
• Exhibit 3-69: Germany: Total Non-fusion Market, 2008-2017
• Exhibit 3-70: Italy: Non-fusion Products Market, 2008-2017
• Exhibit 3-71: Total EU Disc Replacement Market, 2008-2017
• Exhibit 3-72: Total EU Disc Replacement Market, 2008-2017
• Exhibit 3-73: United Kingdom: Total Disc Replacement Market, 2008-2017
• Exhibit 3-74: France: Total Disc Replacement Market, 2008-2017
• Exhibit 3-75: Germany: Total Disc Replacement Market, 2008-2017
• Exhibit 3-76: Italy: Total Disc Replacement Market, 2008-2017
• Exhibit 3-77: Total EU Nucleus Replacement Market, 2008-2017
• Exhibit 3-78: Total EU Nucleus Replacement Market, 2008-2017
• Exhibit 3-79: United Kingdom: Nucleus Replacement Market, 2008-2017
• Exhibit 3-80: France: Nucleus Replacement Market, 2008-2017
• Exhibit 3-81: Germany: Nucleus Replacement Market, 2008-2017
• Exhibit 3-82: Italy: Nucleus Replacement Market, 2008-2017
• Exhibit 3-83: Total EU Interspinous Process Spacers (ISPs) Market, 2008-2017
• Exhibit 3-84: Total EU Interspinous Process Spacers (ISPs) Market, 2008-2017
• Exhibit 3-85: United Kingdom: Interspinous Process Spacers Market, 2008-2017
• Exhibit 3-86: France: Interspinous Process Spacers Market, 2008-2017
• Exhibit 3-87: Germany: Total Spine Surgery Market, 2008-2017
• Exhibit 3-88: Italy: Interspinous Process Spacers Market, 2008-2017
• Exhibit 3-89: Total EU Kyphoplasty Market, 2008-2017
• Exhibit 3-90: Total EU Vertebroplasty/Kyphoplasty Market, 2008-2017
• Exhibit 3-91: United Kingdom: Vertebroplasty/Kyphoplasty Market, 2008-2017
• Exhibit 3-92: France: Vertebroplasty/Kyphoplasty Market, 2008-2017
• Exhibit 3-93: Germany: Vertebroplasty/Kyphoplasty Market, 2008-2017
• Exhibit 3-94: Italy: Vertebroplasty/Kyphoplasty Market, 2008-2017
• Exhibit 3-95: EU Market for Computer Assisted Image Guided Surgery Products, 2008-2017
• Exhibit 3-96: United Kingdom: Image Guided Surgery Market, 2008-2017
• Exhibit 3-97: France: Image Guided Surgery Market, 2008-2017
• Exhibit 3-98: Germany: Image Guided Surgery Market, 2008-2017
• Exhibit 3-99: Italy: Image Guided Surgery Market, 2008-2017
• Exhibit 3-100: Asia-Pacific: Total Spine Surgery Market, 2008-2017
• Exhibit 3-101: Asia-Pacific: Total Spine Surgery Market, 2008-2017
• Exhibit 3-102: Asia-Pacific: Spine Surgery Market Shares, 2008
• Exhibit 3-103: Asia-Pacific: Spinal Fusion and Fixation Market, 2008-2017
• Exhibit 3-104: Asia-Pacific: Spinal Fusion and Fixation Market, 2008-2017
• Exhibit 3-105: Asia-Pacific: Non-fusion Products Market, 2008-2017
• Exhibit 3-106: Asia-Pacific: Non-fusion Products Market, 2008-2017
• Exhibit 3-107: Asia-Pacific: Spinal Fusion vs. Non Fusion Markets, 2008 vs. 2017
• Exhibit 3-108: Asia-Pacific: Total Disc Replacement Market, 2008-2017
• Exhibit 3-109: Asia-Pacific: Total Disc Replacement Market, 2008-2017
• Exhibit 3-110: Asia-Pacific: Nucleus Replacement Market, 2008-2017
• Exhibit 3-111: Asia-Pacific: Nucleus Replacement Market, 2008-2017
• Exhibit 3-112: Asia-Pacific: Interspinous Processes Market, 2008-2017
• Exhibit 3-113: Asia-Pacific: Interspinous Processes Market, 2008-2017
• Exhibit 3-114: Asia-Pacific: Vertebroplasty/Kyphoplasty Market, 2008-2017
• Exhibit 3-115: Asia-Pacific: Vertebroplasty/Kyphoplasty Market, 2008-2017
• Exhibit 3-116: Asia-Pacific: Image Guided Surgery Market, 2008-2017
• Exhibit 3-117: Asia-Pacific: Image Guided Surgery Market, 2008-2017
• Exhibit 3-118: Rest of World Spine Surgery Market Shares, 2008
• Exhibit 3-119: ROW, Spine Surgery Markets, 2008-2017
• Exhibit 3-120: ROW, Spine Surgery Markets, 2008-2017
• Exhibit 3-121: ROW: Fusion and Fixation Market, 2008-2017
• Exhibit 3-122: ROW: Fusion and Fixation Market, 2008-2017
• Exhibit 3-123: ROW: Non-Fusion Market, 2008-2017
• Exhibit 3-124: ROW: Total Disc Replacement Market, 2008-2017
• Exhibit 3-125: ROW: Nucleus Replacement Market, 2008-2017
• Exhibit 3-126: ROW: Interspinous Process Spacers Market, 2008-2017
• Exhibit 3-127: ROW: Vertebroplasty/Kyphoplasty Market, 2008-2017
• Exhibit 3-128: ROW: Image-Guided Surgery Market, 2008-2017

• Exhibit 4-1: CPT spinal fusion codes now allowed by CMS
• Exhibit 4-2: BCBSNC coverage of bone morphogenetic protein
• Exhibit 4-3: New CMS codes for spinal motion preservation
• Exhibit 4-4: Summary of CMS Medicare cost data