全球肝炎策略

Abstract

The unrecognized importance, danger and costs of hepatitis in the 21st century cannot be understated or underestimated. While we were fortunate that, in the latter part of the 20th century, in that hepatitis was fairly well held in check, the impact of the disease on world society is still highly significant and now presenting a major crisis in public health circles.

In his exhaustive analysis of the potential diagnosis, screening and therapeutic markets for hepatitis, Ken Krul, PhD. advises companies to think on a global basis. In this study, Global Hepatitis Strategies Krul examines the potential market, epidemiology (hepatitis patient trends) and technology to provide a clear understanding of the opportunities and challenges awaiting companies competing in this market.

As part of the market analysis this report includes

• Extensive Statistics of Incidence and Prevalence of Hepatitis Across the 6 Major WHO Regions (Americas, Europe, Africa, Western Pacific, Southeast Asia, Eastern Mediterranean)
• Etiology, Prophylaxis, and Therapy for Hepatitis A, B, C, D and E.
• Theoretical Revenues for Diagnosis, Screening and Therapeutics representing the potential marketplace if all screening options are pursued.
• Realistic Market Revenues representing the likely marketplace.
• Global Distribution of Therapeutics and Diagnostics Revenues across Major 6 WHO regions
• Over 40 Figures and Tables making information accessible.

Product managers, Marketing executives at pharmaceutical and diagnostic companies; as well as investment professionals are among those who will find this survey a critical resource.

Table of Contents

CHAPTER ONE: EXECUTIVE SUMMARY

• Market Potential
• Epidemiology
• Technology
• Scope and Methodology

CHAPTER TWO: THE BASICS OF HEPATITIS, VIRUSES, ETIOLOGY AND PATHOLOGY

• Hepatitis A
  • The Virus
  • Etiology
  • Pathology
• Hepatitis B
  • The Virus
  • Etiology Pathology
• Hepatitis C
  • The Virus
  • Etiology
  • Pathology
• Hepatitis D
  • The Virus
  • Etiology
  • Pathology
• Hepatitis E
  • The Virus
  • Etiology
  • Pathology

CHAPTER THREE: EPIDEMILOGY

• Hepatitis A
  • Geographic Patterns
  • Age of Infection
  • U.S. Hepatitis A Cases
• Hepatitis B
  • Geographic Patterns
  • Risk to Children and Infants
  • Vaccines
• Hepatitis C
  • Geographic Patterns
• Hepatitis D
  • Geographic Patterns
• Hepatitis E
  • Geographic Patterns

CHAPTER FOUR: HEPATITIS DIAGNOSIS, PROPHYLAXIS AND THERAPEUTICS

• Hepatitis A
  • Diagnosis
  • Prophylaxis
  • Therapeutics
• Hepatitis B
  • Diagnosis
  • Prophylaxis
  • Therapy
• Hepatitis C
  • Diagnosis
  • Prophylaxis
  • Therapy
• Hepatitis D
  • Diagnosis
  • Prophylaxis
  • Therapy
• Hepatitis E
  • Diagnosis
  • Prophylaxis
  • Therapy

CHAPTER FIVE: STRATEGIC ASSESSMENT AND MARKET ANALYSIS

• Hepatitis Policy
• Comprehensive Prevention Strategy
• Hepatitis C Prevention
• Market Potential
• Theoretical Market Assessment
• Diagnostics and Screening Markets
• Therapeutics: Vaccines and Antivirals
• Pricing Considerations
• Realistic Market Assessment

TABLE OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

• Table 1-1: Estimated Theoretical Global Market Potentials for Hepatitis (All Types) Testing Products and Therapeutics: 2006
• Figure 1-1: Theoretical Distribution of Global Hepatitis (All Types) Testing Products and Therapeutics Market Potential: 2006
• Table 1-2: Estimated Theoretical Global Market Potentials for Hepatitis (All Types) Testing Products: 2006 (Millions)
• Figure 1-2: Theoretical Distribution of Global Hepatitis (All Types) Testing Products (Screening and Diagnosis) Market Potential: 2006
• Table 1-3: Estimated Theoretical Global Market Potentials for Hepatitis (All Types) Therapeutics: 2006
• Figure 1-3: Theoretical Distribution of Global Hepatitis (All Types) Therapeutic Products Market Potential: 2006
• Table 1-4: A Realistic Estimation Global Market Potentials for Hepatitis (All Types) Testing Products and Therapeutics: 2006 (Millions)
• Figure 1-4 The Distribution of Realistic Estimates of Global Hepatitis (All Types) Testing Products and Therapeutics Market Potential: 2006
• Table 1-5 A Realistic Estimation Global Market Potentials for Hepatitis (All Types) Testing Products: 2006 (Millions)
• Figure 1-5: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Testing Products Market Potential: 2006
• Table 1-6 A Realistic Estimation Global Market Potentials for Hepatitis (All Types) Therapeutics: 2006
• Figure 1-6 The Distribution of Realistic Estimates of Global Hepatitis (All Types) Therapeutics Market Potential: 2006
• Table 1-7: Global Prevalence of Hepatitis (All Types): 2006 (Millions)
• Figure 1-7: The Distribution of Global Hepatitis (All Types) Prevalence: 2006

CHAPTER TWO: THE BASICS OF HEPATITIS, VIRUSES, ETIOLOGY AND PATHOLOGY

• Table 2-1 The Hepatitis Viruses

CHAPTER THREE: EPIDEMILOGY

• Table 3-1 Worldwide Endemicity of HAV Infection
• Table 3-2: Prevalence of Hepatitis B in Various regions of the World
• Table 3-3: Hepatitis C Estimated Prevalence and Number Infected by WHO Region: 2000
• Table 3-2: Prevalence of Hepatitis B in Various regions of the World

CHAPTER FOUR: HEPATITIS DIAGNOSIS, PROPHYLAXIS AND THERAPEUTICS

• Table 4-1: HBV Serological Markers in Hepatitis Patients
• Table 4-2: Commercially Available HBV (Antigen and Antibody) Assays
• Table 4-3: Significance of Serological Marker Tests for HBV (HBsAg, antiHBs, anti HBc and Interpretation)
• Table 4-4: Serological Test Findings at Different Stages of HBV Infection and in Convalescence
• Table 4-5: Key Hepatitis B Vaccines* Available Internationally (Producer, Vaccine, Country, Type)
• Table 4-6: General Description of Useful Assay Technologies in the Diagnosis of Hepatitis C
• Table 4-7 Commercially Available HCV (Antigen and Antibody) Assays

CHAPTER FIVE: STRATEGIC ASSESSMENT AND MARKET ANALYSIS

• Table 5-1: Estimated Theoretical Global Market Potentials for Hepatitis (All Types) Testing Products and Therapeutics: 2006
• Figure 5-1: Theoretical Distribution of Global Hepatitis (All Types) Testing Products and Therapeutics Market Potential: 2006
• Table 5-2: Estimated Theoretical Global Market Potentials for Hepatitis (All Types) Testing Products: 2006
• Figure 5-2: Theoretical Distribution of the Total Global Hepatitis (All Types) Testing Products Market Potential: 2006
• Figure 5-3: Theoretical Distribution of Global Hepatitis (All Types) Testing Products Market Potential for Screening: 2006
• Figure 5-4: Theoretical Distribution of Global Hepatitis (All Types) Testing Products Market Potential for Diagnosis: 2006
• Table 5-3: Estimated Theoretical Global Market Potentials for Hepatitis (All Types) Therapeutics: 2006
• Figure 5-5: Theoretical Distribution of Global Hepatitis (All Types) Therapeutic Products Market Potential: 2006
• Figure 5-6: Theoretical Distribution of Global Hepatitis (All Types) Vaccine Market Potential: 2006
• Figure 5-7: Theoretical Distribution of Global Hepatitis (All Types) Antiviral Drug Market Potential: 2006
• Table 5-4: A Realistic Estimation Global Market Potentials for Hepatitis (All Types) Testing Products and Therapeutics: 2006 (in millions)
• Figure 5-8: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Testing Products and Therapeutics Market Potential: 2006
• Table 5-5: A Realistic Estimation Global Market Potentials for Hepatitis (All Types) Testing Products: 2006
• Figure 5-9: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Market Potential for Testing Products: 2006
• Figure 5-10: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Market Potential for Testing Products in Screening: 2006
• Figure 5-11: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Market Potential for Testing Products in Diagnosis: 2006
• Table 5-6: A Realistic Estimation Global Market Potentials for Hepatitis (All Types) Therapeutics: 2006
• Figure 5-12: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Therapeutics Market Potential: 2006
• Figure 5-13: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Therapeutics Market Potential --- Vaccines: 2006
• Figure 5-14: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Therapeutics Market Potential --- Antiviral Drugs: 2006
• Table 5-1: Estimated Theoretical Global Market Potentials for Hepatitis (All Types) Testing Products and Therapeutics: 2006
• Figure 5-1: Theoretical Distribution of Global Hepatitis (All Types) Testing Products and Therapeutics Market Potential: 2006
• Table 5-2: Estimated Theoretical Global Market Potentials for Hepatitis (All Types) Testing Products: 2006
• Figure 5-2: Theoretical Distribution of the Total Global Hepatitis (All Types) Testing Products Market Potential: 2006
• Figure 5-3: Theoretical Distribution of Global Hepatitis (All Types) Testing Products Market Potential for Screening: 2006
• Figure 5-4: Theoretical Distribution of Global Hepatitis (All Types) Testing Products Market Potential for Diagnosis: 2006
• Table 5-3: Estimated Theoretical Global Market Potentials for Hepatitis (All Types) Therapeutics: 2006
• Figure 5-5: Theoretical Distribution of Global Hepatitis (All Types) Therapeutic Products Market Potential: 2006
• Figure 5-6: Theoretical Distribution of Global Hepatitis (All Types) Vaccine Market Potential: 2006
• Figure 5-7 Theoretical Distribution of Global Hepatitis (All Types) Antiviral Drug Market Potential: 2006
• Table 5-4: A Realistic Estimation Global Market Potentials for Hepatitis (All Types) Testing Products and Therapeutics: 2006
• Figure 5-8: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Testing Products and Therapeutics Market Potential: 2006
• Table 5-5: A Realistic Estimation Global Market Potentials for Hepatitis (All Types) Testing Products: 2006
• Figure 5-9: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Market Potential for Testing Products: 2006
• Figure 5-10: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Market Potential for Testing Products in Screening: 2006
• Figure 5-11: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Market Potential for Testing Products in Diagnosis: 2006
• Table 5-6: A Realistic Estimation Global Market Potentials for Hepatitis (All Types) Therapeutics: 2006
• Figure 5-12: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Therapeutics Market Potential: 2006
• Figure 5-13: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Therapeutics Market Potential --- Vaccines: 2006
• Figure 5-14: The Distribution of Realistic Estimates of Global Hepatitis (All Types) Therapeutics Market Potential --- Antiviral Drugs: 2006