Abstract
Biogen Idec is a global research-based company focused on the development, manufacture and commercialisation of novel therapeutics for human health care. This new strategic analysis report provides a complete and critical review of the company and includes unique and independent assessments and forecasts of key products.
On 12th November 2003, Biogen and IDEC Pharmaceuticals merged to create Biogen Idec, the world' s third largest biotechnology group. The move was unusual because, up to now, companies have bought biotechs to generate capital, or they want a specific product. In contrast, Biogen and IDEC had almost equal market capitalisations. The merge was instead a move to strengthen pipelines where both companies faced maturing markets for their main products. The new group has increased research and development funds to target more potential compounds. Thanks to its enhanced commercial and manufacturing capabilities, it should also have more chance of licensing drugs from other companies. In addition, Biogen Idec should be inherently less risky, with two US$1 billion-plus blockbusters, two recently launched medicines and a deeper and broader pipeline of potential products.
Biogen Idec is a global research-based company focused on the development, manufacture and commercialisation of novel therapeutics for human health care. From its headquarters in Cambridge, MA, and facilities across the globe, Biogen Idec' s marketed products reach patients in more than 90 countries worldwide. The company is gaining a reputation as one of the leading biotechnology innovators, particularly in the fields of cancer and immunology.
The failure of the company to attract a takeover offer from the major pharmaceutical companies in 2007, means that Biogen Idec will remain an independent company for the time being. Potential bidders may have been put off by the escalating share price, or the risky bet on Biogen Idec and Elan' s multiple sclerosis drug, Tysabri, following its linking to a rare brain infection that could reduce the drug' s market potential. The successful re-launch and uptake of Tysabri may go some way to allay these fears, however, the perceived wisdom within the industry is that we have seen the end of the so-called ' mega-mergers' and Biogen Idec may have to stand on its own two feet.
Of its key products, Avonex remains the main growth driver alongside Rituxan, supported by the re-launch of Tysabri for multiple sclerosis (MS).
The group' s core asset is its strong pipeline of middle- to late-stage drugs. The pipeline contains some promising line-extensions and biologics for lymphoma, leukaemia and immune disease such as MS, Crohn' s disease and rheumatoid arthritis. Of particular note are lumiliximab, which could be the next new medication for chronic lymphocytic leukaemia, galiximab for non-Hodgkin' s lymphoma, lixivaptan for heart failure, BG-12 for MS and ocrelizumab, which has the potential to take over from Rituxan in rheumatoid arthritis as well as being used in combination with Rituxan for MS.
This new strategic analysis report Biogen Idec: Pipeline · Products · Performance · Potential, provides a complete and critical review of the company and includes unique and independent assessments and forecasts of key products. 4D Pharma reports are updated with the latest data on a continuing basis and the full report is released quarterly. Once a year the report undergoes a major review in line with the company' s year end. Buyers of the print/pdf editions will receive the latest version and quarterly updated reports for a year. Buyers of the web edition receive online access for one year via an easy-to-use interface with fast navigation and a full text search facility. All formats are the same price.
Table of Contents
- Breaking News
- Latest Results
EXECUTIVE SUMMARY
- Introduction
- Current Financial Position
- Company Performance
- Business Segment Performance
- Geographic Segment Performance
- Company Strategy
- R&D Strategy
- Mergers, Acquisitions and Divestitures
- Key Agreements
- Production
- Employees
- Product Performance Forecasts
- Pipeline Analysis
- Other Factors Affecting the Bottom Line
- Conclusions/Outlook
THERAPEUTIC AREA FOCUS
R&D PIPELINE
ONCOLOGY
- Marketed Products
- Rituxan
- R&D Projects
- BIIB021
- Galiximab
- Lumiliximab
- Volociximab
- Growth Forecast
CENTRAL NERVOUS SYSTEM
- Marketed Products
- Avonex
- Tysabri
- R&D Projects
- BIIB014
- BG-12
- CDP323
- Daclizumab
- Ocrelizumab
- Growth Forecast
IMMUNOLOGY
- Marketed Products
- Rituxan
- Fumaderm
- R&D Projects
- LTBR-Fc
- Ocrelizumab
- Growth Forecast
OTHERS
- R&D Projects
- Adentri
- Aviptadil
- Lixivaptan
APPENDIX 1 - FINANCIAL PERFORMANCE
- Full Year Results 2007
APPENDIX 2 - KEY CO RPORATE EVENTS
APPENDIX 3 - KEY AGREEMENTS
- Alnylam Pharmaceuticals Inc
- Astellas Pharma
- Bayer
- Brain Science Institute, Johns Hopkins University
- Cardiokine Biopharma LLC
- Cell Therapeutics Inc
- Celltech Group Plc
- Chemical Diversity Labs Inc
- Fumedica GmbH
- Genaissance Pharmaceuticals Inc
- GlycoFi Inc
- Lexicon Genetics Inc
- mondoBIOTECH AG
- MorphoSys AG
- NeoGenesis Pharmaceuticals Inc
- Neurimmune SubOne AG
- PDL BioPharma Inc
- Pharmaceutical Product Development Inc (PPD)
- Rentschler Biotechnologie GmbH
- Roche
- Schering-Plough
- Sunesis Pharmaceuticals Inc
- Tanox Inc
- The Medicines Company
- UCB
- Vernalis Plc
- Xenogen Corp
APPENDIX 4 - INFRASTRUCTURE
- Research and Development Facilities
- Manufacturing Facilities
APPENDIX 5 - KEY PHARMACEUTICAL SUBSIDI ARIES/JOINT VENTURES
- Subsidiaries
- Joint Ventures
APPENDIX 6 - PRODUCT INDEX
Index of Tables
- Principal Operating Results
- Sales By Business Segment
- Sales By Geographic Area
- Product Sales By Geographic Area
- Long-Term Assets By Geographical Area
- Recent Product Approvals
- Major Therapeutic Areas And Sales
- Major Oncology Products, 2007
- Major Central Nervous System Products, 2007
- Major Immunology Products, 2007
Index of Charts
- Sales By Business Area
- Sales By Geographic Area
- Product Sales By Geographic Area
- Long-Term Assets By Geographical Area
- Sales of Top 4 Products (2003A-2012E)
- Sales of Top Products, 2007
- Rituxan Sales (2002A-2012E)
- Avonex Sales (2003A-2012E)
- Tysabri Sales (2004A-2012E)
- Ocrelizumab Sales (2011E-2015E)
- Rituxan Sales (2002A-2012E)
- Fumaderm Sales (2006A-2012E)
- Ocrelizumab Sales (2011E-2015E)
- Sales, Costs and Operating Income
- Profitability and Research Ratios
- R&D Expenditure and Capital Expenditure
- Current Assets, Liabilities and Ratio
- Assets, Cash and Liquidity
- Employees and Productivity
