Introduction
About one in 100 women of childbearing age have diabetes before pregnancy (pre-existing diabetes). Another 3-5% develop diabetes during pregnancy (gestational diabetes). While diabetes poses some risks in pregnancy, advances in healthcare have greatly improved the outlook for these pregnancies. However, untreated or poorly controlled gestational diabetes can seriously harm the fetus.
Scope of this report
- Review of therapeutic approaches to gestational diabetes mellitus and pre-existing diabetes during pregnancy to protect the health of mother & baby
- Overview of screening and diagnosis guidelines
Research and analysis highlights
The prevalence of congenital anomalies among children of diabetic women is much higher compared to non-diabetic women. The frequency of malformations correlates with the degree of maternal glycemic control. Their prevalence may be reduced by normalization of blood glucose and the maintenance of normal glycemic control throughout the pregnancy.
Key reasons to read this report
- Get insight in the current therapeutic approaches used to treat women with gestational and pre-existing diabetes during pregnancy
- Understand the effect of diabetes in pregnancy outcomes and gauge the impact of diabetic complications in the treatment of pregnant women
ABOUT DATAMONITOR HEALTHCARE
About the Cardiovascular pharmaceutical analysis team
EXECUTIVE SUMMARY
- Introduction
- Scope and coverage of the Brief
- Key findings about the topic
GESTATIONAL DIABETES MELLITUS
- Definition
- Screening and diagnosis
- Prevalence
- Pathophysiology
- The mother
- The fetus
- Management of GDM
- Antepartum management
- Nutrition therapy
- Monitoring effectiveness of therapy
- Intensification of treatment
- Obstetric management
- Assessment of fetal wellbeing
- Timing and mode of delivery
- Management after pregnancy
- The mother
- The child
MANAGEMENT OF PREGNANT DIABETICS
- Preconceptional metabolic control and congenital malformations
- Management of pregnant diabetic women without complications
- Nutrition recommendations
- Exercise
- Insulin
- Hypoglycemia
- Ketosis
- Management of pregnant diabetic women with vascular complications
- Coronary artery disease
- Diabetic nephropathy
- Retinopathy
APPENDIX
- Bibliography
- Disclaimer
List of Tables
- Table 1: Diagnostic criteria for GDM
- Table 2: Glucose targets for antepartum management of GDM
- Table 3: Estimated prevalence of CAD in diabetics in the seven major markets, 2003
- Table 4: Estimated prevalence of diabetic nephropathy in the seven major markets, 2003
- Table 5: Changes in kidney structure and function in diabetic nephropathy
- Table 6: Perinatal outcome of patients with diabetic nephropathy
- Table 7: Estimated prevalence of diabetic retinopathy in the seven major markets, 2003
List of Figures
- Figure 1: Classification of patients at risk of developing GDM
- Figure 2: Recommended screening for patients at risk of developing GDM
- Figure 3: White's classification of diabetes in pregnancy
