Abstract
The drug delivery industry has in recent years become a key partner for pharmaceutical companies in their efforts to maximize the patent lives of successful products. Drug delivery companies not only stand to benefit from patent expiry by providing their reformulation services to pharmaceutical companies, but also by producing their own versions of branded products with improved delivery mechanisms. Thus, post-patent expiry sales can be switched from the ethical manufacturer to the drug delivery sector.
The Global Drug Delivery Market: Research Trends and Market Outlook is an up-to-date guide that assesses the current state of the drug delivery industry and its application to both the pharmaceutical and biotech industries. While the sector is still dominated by oral technologies, drug delivery systems have expanded to include more novel devices such as needleless injectables, PEGylation platforms and microelectromechanical devices. These technological advances extend the duration of a drug's action, increase delivery to target sites, reduce delivery to unwanted sites, and maximize drug absorption.
The expanding market for biotechnology and gene-based products, which by their very nature are difficult to administer, represents an emerging opportunity for drug delivery technologies. These technologies are first expected to come to market as reformulations of existing macromolecular therapies, such as insulin. This report analyzes the markets for oral, inhalable, injectable, transmucosal, transdermal and niche drug delivery technologies as they apply to both biotech and traditional pharmacological compounds.
Key Features of This Report:
- A thorough overview of both marketed and emerging drug delivery technologies set to impact the global pharmaceutical market
- Analysis of the opportunities and threats to the global drug delivery industry
- Profiles of drug delivery companies along with key financial figures and technology/product portfolios
- Market analysis and outlook for the leading drug delivery technologies, including oral, injectable, inhalable, transdermal, transmucosal and niche technologies
- Profiles of key emerging drug delivery technologies and profiles of leading companies, by type of technology
Table of Contents
1 Introducing the Field of Drug Delivery
- 1.1 The Value of Drug Delivery Systems
- 1.2 Drug Delivery and Product Differentiation
- 1.3 Drug Delivery and Patent Extension
- 1.4 The Optimal Time for Reformulation
- 1.5 Optimizing R&D Returns Through Drug Delivery
- 1.6 Opportunities and Threats to the Drug Delivery Sector
- 1.6.1 Opportunities for Growth in the Drug Delivery Sector
- 1.6.2 Threats to Additional Growth in the Drug Delivery Sector
- 1.7 Business Models of Drug Delivery Companies
2 An Overview of Drug Delivery Technologies
- 2.1 Oral Drug Delivery
- 2.1.1 Controlled Release
- 2.1.2 Sustained Release
- 2.1.3 Chronomodulation
- 2.1.4 Rapid Dissolving and Taste-masking Tablets
- 2.1.5 Macromolecular Drug Delivery
- 2.2 Inhalable Drug Delivery
- 2.2.1 Nebulizers
- 2.2.2 Metered Dose Inhalers (MDIs)
- 2.2.3 Dry Powder Inhalers (DPIs)
- 2.2.4 Limitations of Pulmonary Delivery Systems for Systemic Delivery
- 2.2.5 Aqueous Systems
- 2.3 Injectable Drug Delivery
- 2.3.1 Sustained Release Injectable Systems
- 2.3.2 Liposomal Systems
- 2.3.3 Needleless Systems
- 2.4 Transmucosal Drug Delivery
- 2.4.1 Buccal Delivery
- 2.4.2 Nasal
- 2.4.3 Rectal
- 2.4.4 Vaginal
- 2.5 Transdermal Drug Delivery
- 2.5.1 Passive Formulations
- 2.5.2 Active Formulations
- 2.6 Niche Technologies
- 2.6.1 Topical Systems
- 2.6.2 Gene Delivery
- 2.6.3 Implantable Systems
- 2.6.4 Drug Delivery Microchips
- 2.6.5 Nanotechnology
3 Drug Delivery Market Analysis
- 3.1 Key Market Segments
- 3.1.1 Oral Drug Delivery
- 3.1.1.1 Sales of Products Utilizing Oral Drug Delivery Technology
- 3.1.1.2 Key Therapeutic Areas for Oral Drug Delivery
- 3.1.1.3 Key Oral Drug Delivery Products Impacting Global Market
- 3.1.1.4 The Outlook for Oral Drug Delivery Technology
- 3.1.2 Inhalable Drug Delivery
- 3.1.2.1 Sales of Products Utilizing Inhalable Drug Delivery
- 3.1.2.2 Key Therapeutic Areas for Inhalable Drug Delivery
- 3.1.2.3 Key Inhalable Drug Delivery Products Impacting Global Market
- 3.1.2.4 The Outlook for Inhalable Drug Delivery Technology
- 3.1.3 Injectable Drug Delivery
- 3.1.3.1 Sales of Products Utilizing Injectable Drug Delivery Technology
- 3.1.3.2 Key Therapeutic Areas for Injectable Drug Delivery
- 3.1.3.3 Key Injectable Drug Delivery Products Impacting Global Market
- 3.1.3.4 The Outlook for Injectable Drug Delivery Technology
- 3.1.4 Transmucosal Drug Delivery
- 3.1.4.1 Sales of Products Utilizing Transmucosal Drug Delivery Technology
- 3.1.4.2 Key Therapeutic Areas for Transmucosal Delivery
- 3.1.4.3 Key Transmucosal Drug Delivery Products Impacting Global Market
- 3.1.4.4 The Outlook for Transmucosal Drug Delivery Technology
- 3.1.5 Transdermal Drug Delivery
- 3.1.5.1 Sales of Products Utilizing Transdermal Drug Delivery Technology
- 3.1.5.2 Key Therapeutic Areas for Transdermal Drug Delivery
- 3.1.5.3 Key Transdermal Drug Delivery Products Impacting Global Market
- 3.1.5.4 The Outlook for Transdermal Drug Delivery Technology
- 3.1.6 Niche Drug Delivery Technologies
- 3.1.6.1 Sales of Products Utilizing Niche Drug Delivery Technologies
- 3.1.6.2 Key Niche Drug Delivery Technology Product Impacting Global Market
- 3.1.6.3 The Outlook for Niche Drug Delivery Technologies
- 3.1.1 Oral Drug Delivery
4 Emerging Drug Delivery Technologies: Oral Drug Delivery
- 4.1 Key Product Profiles
- 4.2 Key Company Involvement in the Field of Oral Drug Delivery
- 4.2.1 ALZA
- 4.2.2 Biovail
- 4.2.3 Cardinal Health
- 4.2.4 Depomed
- 4.2.5 Emisphere
- 4.2.6 Ethypharm
- 4.2.7 Penwest
5 Emerging Drug Delivery Technologies: Inhalable Drug Delivery
- 5.1 Key Product Profiles
- 5.2 Key Company Involvement in the Field of Inhalable Drug Delivery
- 5.2.1 3M
- 5.2.2 Alkermes
- 5.2.3 Aradigm
- 5.2.4 Nektar
- 5.2.5 SkyePharma
6 Emerging Drug Delivery Technologies: Injectable Drug Delivery
- 6.1 Key Product Profiles
- 6.2 Key Company Involvement in the Field of Injectable Drug Delivery
- 6.2.1 Alkermes
- 6.2.2 ALZA
- 6.2.3 Aradigm
- 6.2.4 Enzon
- 6.2.5 Ethypharm
- 6.2.6 Macromed
- 6.2.7 Nektar
- 6.2.8 QLT
- 6.2.9 SkyePharma
7 Emerging Drug Delivery Technologies: Transmucosal Drug Delivery
- 7.1 Key Company Involvement in the Field of Transmucosal Drug Delivery
- 7.1.1 Generex
- 7.1.2 Nastech
- 7.1.3 Pherin
8 Emerging Drug Delivery Technologies: Transdermal Drug Delivery
- 8.1 Key Product Profiles
- 8.2 Key Company Involvement in the Field of Transdermal Drug Delivery
- 8.2.1 3M
- 8.2.2 Altea Therapeutics
- 8.2.3 ALZA
- 8.2.4 Noven
9 Emerging Drug Delivery Technologies: Niche Drug Delivery Technologies
- 9.1 Key Product Profiles
- 9.2 Key Company Involvement in Niche Drug Delivery Technologies
- 9.2.1 ALZA
- 9.2.2 Connetics
- 9.2.3 Inovio
- 9.2.4 MacroChem
- 9.2.5 NexMed
- 9.2.6 pSivida
- 9.2.7 QLT
- 9.2.8 SkyePharma
10 Key Drug Delivery Company Profiles
- 10.1 3M
- 10.2 Alkermes
- 10.3 Altea Therapeutics
- 10.4 ALZA (Johnson & Johnson)
- 10.5 Aradigm
- 10.6 Bioject
- 10.7 Biovail
- 10.8 Cardinal Health
- 10.9 Cima Labs (Cephalon)
- 10.10 Connetics
- 10.11 CyDex
- 10.12 Delsite Biotechnologies (Carrington Laboratories)
- 10.13 Depomed
- 10.14 DOR BioPharma
- 10.15 DURECT
- 10.16 Emisphere
- 10.17 Enzon
- 10.18 Ethypharm
- 10.19 Generex
- 10.20 Inovio (formerly Genetronics)
- 10.21 IVAX
- 10.22 MacroChem
- 10.23 MacroMed
- 10.24 Nastech
- 10.25 Nektar
- 10.26 NexMed
- 10.27 Noven
- 10.28 Penwest
- 10.29 Pherin Pharmaceuticals
- 10.30 QLT
- 10.31 SkyePharma
- 10.32 Watson Pharmaceuticals
11 Leading Pharmaceutical Companies Utilizing Drug Delivery Technologies
- 11.1 Pfizer
- 11.2 GlaxoSmithKline
- 11.3 Sanofi-Aventis
- 11.4 Merck
- 11.5 Johnson & Johnson
- 11.6 AstraZeneca
- 11.7 Novartis
- 11.8 Bristol-Myers Squibb
- 11.9 Wyeth
- 11.10 Abbott Labs
